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D1Pas1 | Putative ATP-dependent RNA helicase Pl10; Putative ATP-dependent RNA helicase. Possible role in a key step of the spermatogenic process; Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. (660 aa) | ||||
Dhx29 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1365 aa) | ||||
Mrpl3 | 39S ribosomal protein L3, mitochondrial; Belongs to the universal ribosomal protein uL3 family. (348 aa) | ||||
Rpsa | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa) | ||||
Mrps22 | 28S ribosomal protein S22, mitochondrial. (359 aa) | ||||
Rpl4 | 60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family. (419 aa) | ||||
Mrps31 | 28S ribosomal protein S31, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS31 family. (384 aa) | ||||
Rps4x | 40S ribosomal protein S4, X isoform; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa) | ||||
Ndufab1 | Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity). (156 aa) | ||||
Rps3 | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit (By similarity). Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (By similarity). Displays high binding affinity for 7,8-dihydro-8- oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (By similarity). Has also been shown to bind with similar affinity to intact and damaged DNA (By similarity). S [...] (243 aa) | ||||
Mrpl46 | 39S ribosomal protein L46, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL46 family. (283 aa) | ||||
Mrps11 | 28S ribosomal protein S11, mitochondrial; Belongs to the universal ribosomal protein uS11 family. (191 aa) | ||||
Rpl28 | 60S ribosomal protein L28; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL28 family. (137 aa) | ||||
Mrpl51 | 39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family. (128 aa) | ||||
Mrpl19 | 39S ribosomal protein L19, mitochondrial; Belongs to the bacterial ribosomal protein bL19 family. (292 aa) | ||||
Mrps33 | 28S ribosomal protein S33, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS33 family. (106 aa) | ||||
Rpl6 | 60S ribosomal protein L6; Component of the large ribosomal subunit. (296 aa) | ||||
Mrpl33 | 39S ribosomal protein L33, mitochondrial; Belongs to the bacterial ribosomal protein bL33 family. (65 aa) | ||||
Mrpl20 | 39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family. (149 aa) | ||||
Mrps15 | 28S ribosomal protein S15, mitochondrial; Belongs to the universal ribosomal protein uS15 family. (258 aa) | ||||
Nsun4 | 5-methylcytosine rRNA methyltransferase NSUN4; Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA at position 911; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by [...] (381 aa) | ||||
Mrpl37 | 39S ribosomal protein L37, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL37 family. (423 aa) | ||||
Mrpl9 | 39S ribosomal protein L9, mitochondrial; Belongs to the bacterial ribosomal protein bL9 family. (265 aa) | ||||
Rps3a1 | 40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. (264 aa) | ||||
Rps20 | 40S ribosomal protein S20. (119 aa) | ||||
Zcchc17 | Nucleolar protein of 40 kDa. (241 aa) | ||||
Malsu1 | Mitochondrial assembly of ribosomal large subunit protein 1; Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S riboso [...] (228 aa) | ||||
Mrps26 | 28S ribosomal protein S26, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS26 family. (200 aa) | ||||
Rpl27a | 60S ribosomal protein L27a. (148 aa) | ||||
Gm45713 | Predicted gene 45713; Belongs to the universal ribosomal protein uL13 family. (446 aa) | ||||
Rpl18 | 60S ribosomal protein L18; Component of the large ribosomal subunit. (188 aa) | ||||
Rps12 | 40S ribosomal protein S12. (132 aa) | ||||
Rps18-ps5 | Ribosomal protein S18, pseudogene 5; Belongs to the universal ribosomal protein uS13 family. (152 aa) | ||||
Mrpl32 | 39S ribosomal protein L32, mitochondrial; Belongs to the bacterial ribosomal protein bL32 family. (187 aa) | ||||
Rps24 | 40S ribosomal protein S24; Required for processing of pre-rRNA and maturation of 40S ribosomal subunits. (133 aa) | ||||
Eif2a | Eukaryotic translation initiation factor 2A, N-terminally processed; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (581 aa) | ||||
Mrps5 | 28S ribosomal protein S5, mitochondrial; Belongs to the universal ribosomal protein uS5 family. (432 aa) | ||||
Mterf4 | Transcription termination factor 4, mitochondrial; Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S (By similarity). Targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit; Belongs to the mTERF family. (346 aa) | ||||
Mrpl44 | 39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL44 subfamily. (333 aa) | ||||
Mrpl30 | 39S ribosomal protein L30, mitochondrial; Belongs to the universal ribosomal protein uL30 family. (160 aa) | ||||
Rps26 | 40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa) | ||||
Mrpl11 | 39S ribosomal protein L11, mitochondrial; Belongs to the universal ribosomal protein uL11 family. (192 aa) | ||||
Mrpl21 | 39S ribosomal protein L21, mitochondrial. (216 aa) | ||||
Mrps18b | 28S ribosomal protein S18b, mitochondrial. (254 aa) | ||||
Mrpl27 | 39S ribosomal protein L27, mitochondrial; Belongs to the bacterial ribosomal protein bL27 family. (148 aa) | ||||
Mrpl28 | 39S ribosomal protein L28, mitochondrial; Belongs to the bacterial ribosomal protein bL28 family. (257 aa) | ||||
Mrps18a | 28S ribosomal protein S18a, mitochondrial; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily. (196 aa) | ||||
Mrpl14 | 39S ribosomal protein L14, mitochondrial; May form part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1, intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation. (145 aa) | ||||
Mrps23 | 28S ribosomal protein S23, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS23 family. (177 aa) | ||||
Mrpl40 | 39S ribosomal protein L40, mitochondrial. (206 aa) | ||||
Rpl24 | 60S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family. (157 aa) | ||||
Mief1 | Mitochondrial dynamics protein MID51; Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assem [...] (463 aa) | ||||
Mrpl57 | Ribosomal protein 63, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL63 family. (102 aa) | ||||
Mrps30 | 28S ribosomal protein S30, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL65 family. (442 aa) | ||||
Mrpl36 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. (102 aa) | ||||
Mrpl22 | 39S ribosomal protein L22, mitochondrial; Belongs to the universal ribosomal protein uL22 family. (206 aa) | ||||
Rack1 | Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits (By similarity). Binds to and stabilizes a [...] (317 aa) | ||||
Mrpl45 | 39S ribosomal protein L45, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL45 family. (306 aa) | ||||
Rpl19 | 60S ribosomal protein L19. (196 aa) | ||||
Mrps18c | 28S ribosomal protein S18c, mitochondrial; Belongs to the bacterial ribosomal protein bS18 family. (143 aa) | ||||
Mrpl52 | 39S ribosomal protein L52, mitochondrial. (121 aa) | ||||
Rpl14 | 60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. (217 aa) | ||||
Mrpl13 | 39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. (178 aa) | ||||
Rpl3l | Ribosomal protein L3-like; Belongs to the universal ribosomal protein uL3 family. (407 aa) | ||||
Rpl26 | 60S ribosomal protein L26; Component of the large ribosomal subunit. (145 aa) | ||||
Mrpl16 | 39S ribosomal protein L16, mitochondrial; Belongs to the universal ribosomal protein uL16 family. (251 aa) | ||||
Gm6133 | Predicted gene 6133; Belongs to the universal ribosomal protein uL22 family. (190 aa) | ||||
Rpl9-ps6 | Ribosomal protein L9, pseudogene 6. (192 aa) | ||||
Gm10260 | Ribosomal protein S18, pseudogene 6; Belongs to the universal ribosomal protein uS13 family. (152 aa) | ||||
Rps13 | 40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa) | ||||
Rpl10-ps3 | Ribosomal protein L10, pseudogene 3. (214 aa) | ||||
Rps27 | Ribosomal protein S27. (84 aa) | ||||
ENSMUSP00000158993 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (115 aa) | ||||
Rps14 | 40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa) | ||||
Gm5244 | Predicted pseudogene 5244; Belongs to the eukaryotic ribosomal protein P1/P2 family. (113 aa) | ||||
Rpl17 | 60S ribosomal protein L17; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL22 family. (184 aa) | ||||
Gm49804 | Predicted gene, 49804. (287 aa) | ||||
Gm49711 | Predicted gene, 49711. (117 aa) | ||||
Rpl8 | 60S ribosomal protein L8; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL2 family. (257 aa) | ||||
ENSMUSP00000154304 | Uncharacterized protein; Belongs to the complex I LYR family. (70 aa) | ||||
Rpl36a-ps1 | Ribosomal protein L36A, pseudogene 1; Belongs to the eukaryotic ribosomal protein eL42 family. (106 aa) | ||||
Mcts1 | Malignant T-cell-amplified sequence 1; Anti-oncogene that plays a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent growth; shortens the duration of G1 transit time and G1/S transition. When constitutively expressed, increases CDK4 and CDK6 kinases activity and CCND1/cyclin D1 protein level, as well as G1 cyclin/CDK complex formation. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated diss [...] (181 aa) | ||||
Rpl13 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (211 aa) | ||||
Ddx3x | ATP-dependent RNA helicase DDX3X; Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo-and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially double-stranded DNA with a preference for 5'-single-stranded DNA overhangs. Binds RNA G-quadruplex (rG4s) structures, including those located in the 5'-UTR of NRAS mRNA. Involved in many cellular processes, which do not necessarily require its ATPase/helicase catalytic activities. Involved in transcription regulation. Positively regulates CDKN1A/WAF1/CIP1 t [...] (662 aa) | ||||
Mrpl10 | 39S ribosomal protein L10, mitochondrial; Belongs to the universal ribosomal protein uL10 family. (262 aa) | ||||
Mrpl2 | 39S ribosomal protein L2, mitochondrial; Belongs to the universal ribosomal protein uL2 family. (306 aa) | ||||
Mrpl4 | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. (294 aa) | ||||
Rps11 | 40S ribosomal protein S11. (158 aa) | ||||
Mrpl49 | 39S ribosomal protein L49, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL49 family. (166 aa) | ||||
Rplp1 | 60S acidic ribosomal protein P1; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa) | ||||
Rps18 | 40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA. (152 aa) | ||||
Uba52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) | ||||
Rps27l | 40S ribosomal protein S27. (105 aa) | ||||
Rps15a | 40S ribosomal protein S15a; Structural component of the ribosome. Required for proper erythropoiesis; Belongs to the universal ribosomal protein uS8 family. (130 aa) | ||||
Mrps24 | 28S ribosomal protein S24, mitochondrial; Belongs to the universal ribosomal protein uS3 family. (167 aa) | ||||
Rpl22 | 60S ribosomal protein L22. (128 aa) | ||||
Mrpl17 | 39S ribosomal protein L17, mitochondrial. (176 aa) | ||||
Rpl29 | 60S ribosomal protein L29; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL29 family. (160 aa) | ||||
Rpl12 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA. (165 aa) | ||||
Mrpl58 | Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (By similarity). (206 aa) | ||||
Mrpl48 | 39S ribosomal protein L48, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL48 family. (211 aa) | ||||
Rpl13a | 60S ribosomal protein L13a; Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions (By similarity). Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as cerupla [...] (203 aa) | ||||
Mrpl15 | 39S ribosomal protein L15, mitochondrial. (295 aa) | ||||
Mrps25 | 28S ribosomal protein S25, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS25 family. (171 aa) | ||||
Mrpl24 | 39S ribosomal protein L24, mitochondrial; Belongs to the universal ribosomal protein uL24 family. (216 aa) | ||||
Mrps10 | 28S ribosomal protein S10, mitochondrial; Belongs to the universal ribosomal protein uS10 family. (201 aa) | ||||
Mrpl1 | 39S ribosomal protein L1, mitochondrial. (336 aa) | ||||
Mrps17 | 28S ribosomal protein S17, mitochondrial; Belongs to the universal ribosomal protein uS17 family. (120 aa) | ||||
Mrpl39 | 39S ribosomal protein L39, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL39 family. (336 aa) | ||||
Rpl39 | 60S ribosomal protein L39; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) | ||||
Rpl35a | 60S ribosomal protein L35a; Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site. (110 aa) | ||||
Rps10 | 40S ribosomal protein S10; Component of the 40S ribosomal subunit. (165 aa) | ||||
Mrpl53 | 39S ribosomal protein L53, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL53 family. (118 aa) | ||||
Rpl9 | 60S ribosomal protein L9; Belongs to the universal ribosomal protein uL6 family. (192 aa) | ||||
Rpl36a | Ribosomal protein L36A. (106 aa) | ||||
Rpl36al | 60S ribosomal protein L36a. (106 aa) | ||||
Rpl30 | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. (115 aa) | ||||
Mrpl55 | 39S ribosomal protein L55, mitochondrial. (134 aa) | ||||
Rps9 | 40S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa) | ||||
Rps5 | 40S ribosomal protein S5, N-terminally processed; Belongs to the universal ribosomal protein uS7 family. (204 aa) | ||||
Rps19 | 40S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family. (145 aa) | ||||
Rps16 | 40S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa) | ||||
Rpl27 | 60S ribosomal protein L27; Component of the large ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (By similarity). (136 aa) | ||||
Rpl38 | 60S ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa) | ||||
Mrpl38 | 39S ribosomal protein L38, mitochondrial. (380 aa) | ||||
Rpl10l | 60S ribosomal protein L10-like; Belongs to the universal ribosomal protein uL16 family. (214 aa) | ||||
Gm3550 | 60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family. (160 aa) | ||||
Mcts2 | Malignant T-cell-amplified sequence 2. (181 aa) | ||||
Rpl7a | 60S ribosomal protein L7a. (266 aa) | ||||
Rps27a | Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa) | ||||
Rps6 | 40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. (249 aa) | ||||
Gm2000 | Predicted gene 2000. (123 aa) | ||||
Rps8 | 40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa) | ||||
Rpl11 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (178 aa) | ||||
Rpl23a | 60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA (By similarity). May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination (By similarity); Belongs to the universal ribosomal protein uL23 family. (156 aa) | ||||
Rpl23 | 60S ribosomal protein L23. (140 aa) | ||||
Larp4 | La-related protein 4; RNA binding protein that binds to the poly-A tract of mRNA molecules. Associates with the 40S ribosomal subunit and with polysomes. Plays a role in the regulation of mRNA translation. Plays a role in the regulation of cell morphology and cytoskeletal organization. (719 aa) | ||||
Gm49368 | Predicted gene, 49368; Belongs to the integrin alpha chain family. (1232 aa) | ||||
Mrpl43 | 39S ribosomal protein L43, mitochondrial. (159 aa) | ||||
Rpl7l1 | 60S ribosomal protein L7-like 1; Belongs to the universal ribosomal protein uL30 family. (246 aa) | ||||
Rps2 | 40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (293 aa) | ||||
Hba-a2 | Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. (142 aa) | ||||
Dap3 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. Belongs to the mitochondrion-specific ribosomal protein mS29 family. (396 aa) | ||||
Gm11808 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa) | ||||
Rpl34 | 60S ribosomal protein L34; Component of the large ribosomal subunit. (117 aa) | ||||
B3galt4 | Beta-1,3-galactosyltransferase 4; Involved in GM1/GD1B/GA1 ganglioside biosynthesis. Belongs to the glycosyltransferase 31 family. (371 aa) | ||||
Rpl31 | 60S ribosomal protein L31; Belongs to the eukaryotic ribosomal protein eL31 family. (125 aa) | ||||
Rplp0 | 60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa) | ||||
Isg15 | Ubiquitin-like protein ISG15; Ubiquitin-like protein which plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein. ISGylation involves a cascade of enzymatic reactions involving E1, E2, and E3 enzymes which catalyze the conjugation of ISG15 to a lysine residue in the target protein. Its target proteins include SERPINA3G/SPI2A, JAK1, MAPK3/ERK1, PLCG1, TRIM25, STAT5A, MAPK1/ERK2 and globin. Can also isgylate: DDX58/RIG-I which inhibits its function in antiviral sign [...] (161 aa) | ||||
Rpl10 | 60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development. (214 aa) | ||||
Rplp2 | 60S acidic ribosomal protein P2; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. (115 aa) | ||||
Aurkaip1 | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down- regulation through proteasome-dependent degradation; Belongs to the mitochondrion-specific ribosomal protein mS38 family. (200 aa) | ||||
Rpl5 | 60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (297 aa) | ||||
Ptcd3 | Pentatricopeptide repeat domain-containing protein 3, mitochondrial; Mitochondrial RNA-binding protein that has a role in mitochondrial translation. (685 aa) | ||||
Rpl3 | 60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes. (403 aa) | ||||
Rpl35 | 60S ribosomal protein L35; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL29 family. (123 aa) | ||||
Rps17 | 40S ribosomal protein S17; Belongs to the eukaryotic ribosomal protein eS17 family. (135 aa) | ||||
Rpl36 | 60S ribosomal protein L36; Component of the large ribosomal subunit. (105 aa) | ||||
Rps25 | 40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (125 aa) | ||||
Rpl15 | 60S ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa) | ||||
Mrpl18 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA (By similarity). (180 aa) | ||||
Mrpl42 | 39S ribosomal protein L42, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL42 family. (142 aa) | ||||
Npm1 | Nucleophosmin; Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. M [...] (292 aa) | ||||
Rps7 | 40S ribosomal protein S7; Required for rRNA maturation. (194 aa) | ||||
Rpl7 | 60S ribosomal protein L7; Component of the large ribosomal subunit (By similarity). Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity); Belongs to the universal ribosomal protein uL30 family. (270 aa) | ||||
Mrps12 | 28S ribosomal protein S12, mitochondrial; Belongs to the universal ribosomal protein uS12 family. (139 aa) | ||||
Rps28 | 40S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family. (69 aa) | ||||
Rpl41 | Ribosomal protein L41. (25 aa) | ||||
Rpl36-ps4 | Ribosomal protein L36, pseudogene 4. (117 aa) | ||||
Fau | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. (133 aa) | ||||
Gm6525 | Predicted pseudogene 6525. (106 aa) | ||||
Rpl32 | 60S ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family. (135 aa) | ||||
Mrps14 | 28S ribosomal protein S14, mitochondrial; Belongs to the universal ribosomal protein uS14 family. (128 aa) | ||||
Chchd1 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 1; Belongs to the mitochondrion-specific ribosomal protein mS37 family. (118 aa) | ||||
Rps15 | 40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (145 aa) | ||||
Mrps21 | 28S ribosomal protein S21, mitochondrial; Belongs to the bacterial ribosomal protein bS21 family. (87 aa) | ||||
Mrpl35 | 39S ribosomal protein L35, mitochondrial. (188 aa) | ||||
Eif2d | Eukaryotic translation initiation factor 2D; Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its [...] (570 aa) | ||||
Mrpl50 | 39S ribosomal protein L50, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL50 family. (159 aa) | ||||
Mrps27 | 28S ribosomal protein S27, mitochondrial; RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues. (415 aa) | ||||
Rps27rt | 40S ribosomal protein S27; Component of the small ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 18S rRNAs (By similarity). (84 aa) | ||||
Nsun3 | tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial; Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt- tRNA(Met). mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5- formylcytosine (f(5)c) at this position. mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation; Belongs to the class I-like SAM-bind [...] (348 aa) | ||||
Rpl37a | 60S ribosomal protein L37a; Belongs to the eukaryotic ribosomal protein eL43 family. (92 aa) | ||||
Rps21 | 40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (83 aa) | ||||
Rpl18a | 60S ribosomal protein L18a. (176 aa) | ||||
Mrps9 | 28S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family. (390 aa) | ||||
Mrps16 | 28S ribosomal protein S16, mitochondrial; Belongs to the bacterial ribosomal protein bS16 family. (135 aa) | ||||
Rps23 | 40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (143 aa) | ||||
Mrps7 | 28S ribosomal protein S7, mitochondrial; Belongs to the universal ribosomal protein uS7 family. (242 aa) | ||||
Rpl10a | 60S ribosomal protein L10a; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL1 family. (217 aa) | ||||
Mrps35 | 28S ribosomal protein S35, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS35 family. (320 aa) | ||||
Mrpl47 | 39S ribosomal protein L47, mitochondrial; Belongs to the universal ribosomal protein uL29 family. (252 aa) | ||||
Rpl37 | 60S ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (97 aa) | ||||
Mrps34 | 28S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation. Belongs to the mitochondrion-specific ribosomal protein mS34 family. (218 aa) | ||||
Mrpl34 | 39S ribosomal protein L34, mitochondrial; Belongs to the bacterial ribosomal protein bL34 family. (92 aa) | ||||
Mrpl12 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. (201 aa) | ||||
Mrpl41 | 39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. (135 aa) | ||||
Rpl39l | Ribosomal protein L39-like. (51 aa) | ||||
Rpl21 | 60S ribosomal protein L21; Component of the large ribosomal subunit. (160 aa) | ||||
Mrpl54 | 39S ribosomal protein L54, mitochondrial. (135 aa) | ||||
Mrpl23 | 39S ribosomal protein L23, mitochondrial; Belongs to the universal ribosomal protein uL23 family. (146 aa) | ||||
Rps29 | 40S ribosomal protein S29. (56 aa) | ||||
Mrps28 | 28S ribosomal protein S28, mitochondrial; Belongs to the bacterial ribosomal protein bS1 family. (186 aa) | ||||
Mpv17l2 | Mpv17-like protein 2; Required for the assembly and stability of the mitochondrial ribosome (By similarity). Is a positive regulator of mitochondrial protein synthesis (By similarity). (200 aa) | ||||
Gadd45gip1 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. (222 aa) | ||||
Mrps6 | 28S ribosomal protein S6, mitochondrial; Belongs to the bacterial ribosomal protein bS6 family. (125 aa) | ||||
Mrps2 | 28S ribosomal protein S2, mitochondrial; Required for mitoribosome formation and stability, and mitochondrial translation. (291 aa) |