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| | Krtap5-1 | Keratin-associated protein 5-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 5 family. (230 aa) |
| | Krt87 | Keratin, type II cuticular 87; Belongs to the intermediate filament family. (495 aa) |
| | Krt77 | Keratin, type II cytoskeletal 1b. (572 aa) |
| | Krt86 | Keratin, type II cuticular Hb6; Belongs to the intermediate filament family. (486 aa) |
| | Krtap12-1 | Keratin associated protein 12-1. (130 aa) |
| | Gm10272 | Predicted gene 10272. (110 aa) |
| | Gm11559 | Predicted gene 11559. (191 aa) |
| | Gm11563 | Predicted gene 11563. (168 aa) |
| | Krtap3-2 | Keratin-associated protein 3-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 3 family. (99 aa) |
| | Krtap3-3 | Keratin associated protein 3-3. (99 aa) |
| | Krtap31-1 | Keratin-associated protein 31-1. (177 aa) |
| | Krtap9-1 | Keratin-associated protein 9-1. (186 aa) |
| | Tchp | Trichoplein keratin filament-binding protein; Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (By similarity). Is a negative regulator of ciliogenesis (By similarity). Belongs to the TCHP family. (497 aa) |
| | Gm9507 | Predicted gene 9507. (223 aa) |
| | Krtap5-5 | Keratin-associated protein 5-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 5 family. (241 aa) |
| | Krt76 | Keratin, type II cytoskeletal 2 oral; Probably contributes to terminal cornification. (594 aa) |
| | Gm11567 | Predicted gene 11567. (195 aa) |
| | Krtap4-6 | Keratin associated protein 4-6. (195 aa) |
| | Krtap1-4 | Keratin-associated protein 1-4. (188 aa) |
| | Fbf1 | Fas-binding factor 1; Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis (By similarity). (1173 aa) |
| | Krt10 | Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Belongs to the intermediate filament family. (561 aa) |
| | Gm11555 | Predicted gene 11555. (175 aa) |
| | Krtap1-3 | Keratin-associated protein 1-3. (173 aa) |
| | Gm11939 | Predicted gene 11939. (99 aa) |
| | Krtap16-1 | Keratin-associated protein 16-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 16 family. (502 aa) |
| | Krtap29-1 | Keratin-associated protein 29-1; Belongs to the KRTAP type 10 family. (342 aa) |
| | Krtap9-5 | Keratin-associated protein 9-5. (358 aa) |
| | Gm11565 | Predicted gene 11565. (156 aa) |
| | 2300003K06Rik | RIKEN cDNA 2300003K06 gene. (262 aa) |
| | Gm11564 | Predicted gene 11564. (201 aa) |
| | Gm11554 | Predicted gene 11554. (190 aa) |
| | Gm11569 | Predicted gene 11569. (180 aa) |
| | Gm11596 | Predicted gene 11596. (205 aa) |
| | Krtap4-9 | Keratin associated protein 4-9. (244 aa) |
| | Krt36 | Keratin, type I cuticular Ha6; Belongs to the intermediate filament family. (473 aa) |
| | Gm11568 | Predicted gene 11568. (211 aa) |
| | Krtap4-16 | Keratin associated protein 4-16. (202 aa) |
| | Krtap4-8 | Keratin associated protein 4-8. (209 aa) |
| | Gm11595 | Predicted gene 11595. (289 aa) |
| | Krt78 | Keratin 78; Belongs to the intermediate filament family. (1068 aa) |
| | Fam83h | Protein FAM83H; May play a major role in the structural organization and calcification of developing enamel. May play a role in keratin cytoskeleton disassembly by recruiting CSNK1A1 to keratin filaments. Thereby, it may regulate epithelial cell migration. Belongs to the FAM83 family. (1209 aa) |
| | Csnk1a1 | Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (By similarity). (325 aa) |
| | Gm3233 | Predicted gene 3233. (230 aa) |
| | Gm3238 | Predicted gene 3238. (230 aa) |
| | Gm7138 | Predicted gene 7138. (230 aa) |
| | Gm3250 | Predicted gene 3250. (230 aa) |
| | Gm10142 | Predicted gene 10142. (120 aa) |
| | Gm19402 | Predicted gene, 19402. (266 aa) |
| | Gm19668 | Predicted gene, 19668. (248 aa) |
| | Gm7137 | Predicted gene 7137. (236 aa) |
| | Gm10100 | Predicted gene 10100. (120 aa) |
| | Krtap10-4 | Keratin associated protein 10-4. (221 aa) |
| | Krtap5-2 | Keratin-associated protein 5-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 5 family. (367 aa) |
| | Krtap5-3 | Keratin-associated protein 5-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 5 family. (356 aa) |
| | Gm40460 | Predicted gene, 39115. (244 aa) |
| | Gm7579 | Predicted gene 7579. (243 aa) |
| | Gm10153 | Predicted gene 10153. (320 aa) |
| | Gm45337 | Predicted gene 45337. (263 aa) |
| | Gm45618 | Predicted gene 45618. (219 aa) |
| | Gm4553 | Predicted gene 4553. (284 aa) |
| | Gm39115 | Predicted gene, 39115. (232 aa) |
| | Gm29735 | Predicted gene, 29735. (219 aa) |
| | Gm49918 | Predicted gene, 49918. (240 aa) |
| | Gm10318 | Predicted gene 10318. (225 aa) |
| | Gm9639 | Predicted gene 9639. (225 aa) |
| | Gm9736 | Predicted gene 9736. (277 aa) |
| | Krtap10-10 | Keratin-associated protein 10-10. (217 aa) |
| | Gm3285 | Predicted gene 3285. (201 aa) |
| | Gm9508 | Predicted gene 9508. (230 aa) |
| | Gm18596 | Predicted gene, 18596. (280 aa) |
| | Gm36176 | Predicted gene, 36176. (158 aa) |
| | Eppk1 | Epiplakin; Cytoskeletal linker protein that connects to intermediate filaments and controls their reorganization in response to stress. In response to mechanical stress like wound healing, is associated with the machinery for cellular motility by slowing down keratinocyte migration and proliferation and accelerating keratin bundling in proliferating keratinocytes thus contributing to tissue architecture. However in wound healing in corneal epithelium also positively regulates cell differentiation and proliferation and negatively regulates migration thereby controlling corneal epitheliu [...] (3458 aa) |
| | Gm5478 | Predicted pseudogene 5478; Belongs to the intermediate filament family. (535 aa) |
| | Casp14 | Caspase-14 subunit p20, intermediate form; Non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin. In vitro is equally active on the synthetic caspase substrates WEHD-ACF and IETD-AFC. Involved in processing of prosaposin in the epidermis. May be involved in retinal pigment epithelium cell barrier function (By similarity). Belongs to the peptidase C14A family. (257 aa) |
| | Krt14 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. (484 aa) |
| | Krt13 | Keratin, type I cytoskeletal 13. (437 aa) |
| | Krt5 | Keratin, type II cytoskeletal 5. (580 aa) |
| | Krt71 | Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. (524 aa) |
| | Krt2 | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin. (707 aa) |
| | Krt82 | Keratin, type II cuticular Hb2; Belongs to the intermediate filament family. (516 aa) |
| | Krt90 | Keratin 90; Belongs to the intermediate filament family. (538 aa) |
| | Krt83 | Keratin 83; Belongs to the intermediate filament family. (479 aa) |
| | Krt84 | Keratin, type II cuticular Hb4; Belongs to the intermediate filament family. (603 aa) |
| | Krt88 | Keratin 88; Belongs to the intermediate filament family. (171 aa) |
| | Krt6b | Keratin, type II cytoskeletal 6B; Belongs to the intermediate filament family. (554 aa) |
| | Krt6a | Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. (553 aa) |
| | Krt1 | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. (637 aa) |
| | Krt4 | Keratin, type II cytoskeletal 4. (525 aa) |
| | Krt79 | Keratin, type II cytoskeletal 79; Belongs to the intermediate filament family. (531 aa) |
| | Krt18 | Keratin, type I cytoskeletal 18; When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. (423 aa) |
| | Krt8 | Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle; Belongs to the intermediate filament family. (490 aa) |
| | Krt75 | Keratin, type II cytoskeletal 75; Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle (By similarity). (551 aa) |
| | Krt25 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). Plays a role in the cytoskeleton organization (By similarity). (446 aa) |
| | Krtap24-1 | Keratin-associated protein 24-1. (248 aa) |
| | Krtap1-5 | Keratin-associated protein 1-5. (122 aa) |
| | Krtap4-7 | Keratin associated protein 4-7. (168 aa) |
| | Krtap4-13 | Keratin associated protein 4-13. (165 aa) |
| | Krtap3-1 | Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 3 family. (98 aa) |
| | Krtap31-2 | Keratin-associated protein 31-2. (177 aa) |
| | Krt9 | Keratin, type I cytoskeletal 9; May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly (By similarity). Plays an essential role in the correct development of sperm; Belongs to the intermediate filament family. (743 aa) |
| | Krtap4-2 | Keratin-associated protein 4-2. (167 aa) |
| | Krt81 | Keratin, type II cuticular Hb1. (481 aa) |
| | Krtap9-3 | Keratin-associated protein 9-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family. (136 aa) |
| | Gm5414 | Type II keratin Kb14; Belongs to the intermediate filament family. (552 aa) |
| | Krtap5-4 | Keratin-associated protein 5-4; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. (223 aa) |
| | Krt73 | Keratin, type II cytoskeletal 73; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (By similarity). (539 aa) |
| | Krt72 | Keratin, type II cytoskeletal 72; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (By similarity). (520 aa) |
| | Krt7 | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. (457 aa) |
| | Gm11938 | Keratin-associated protein 2-4. (131 aa) |
| | Gm11562 | Predicted gene 11562. (136 aa) |
| | Krtap2-4 | Keratin associated protein 2-4. (131 aa) |
| | Gm10024 | Keratin-associated protein 12-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity). (119 aa) |
| | Gm11937 | Predicted gene 11937. (131 aa) |
| | Krt80 | Keratin, type II cytoskeletal 80; Belongs to the intermediate filament family. (452 aa) |
| | Gm4559 | ENSMUSG00000056885 protein. (199 aa) |
| | Krt17 | Keratin, type I cytoskeletal 17; Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epit [...] (433 aa) |
| | Krtap4-1 | Keratin associated protein 4-1. (169 aa) |
| | Gper1 | G-protein coupled estrogen receptor 1; G-protein coupled estrogen receptor that binds to 17-beta- estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine [...] (375 aa) |
