(8 nodes) Catalase complex network (Mus musculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Gpx5	Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. (221 aa)
	Gpx7	Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks (By similarity). (186 aa)
	Gpx1	Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. (201 aa)
	Gpx6	Glutathione peroxidase 6; Belongs to the glutathione peroxidase family. (221 aa)
	Gpx8	Probable glutathione peroxidase 8; Belongs to the glutathione peroxidase family. (209 aa)
	Gpx3	Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. (226 aa)
	Gpx2	Glutathione peroxidase 2. (190 aa)
	Cat	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. (527 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cat	Gpx1	ENSMUSP00000028610	ENSMUSP00000081010	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown.	0.547
Cat	Gpx2	ENSMUSP00000028610	ENSMUSP00000081012	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	Glutathione peroxidase 2.	0.504
Cat	Gpx3	ENSMUSP00000028610	ENSMUSP00000081011	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.	0.513
Cat	Gpx5	ENSMUSP00000028610	ENSMUSP00000106117	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.	0.508
Cat	Gpx6	ENSMUSP00000028610	ENSMUSP00000004453	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	Glutathione peroxidase 6; Belongs to the glutathione peroxidase family.	0.508
Cat	Gpx7	ENSMUSP00000028610	ENSMUSP00000030332	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks (By similarity).	0.607
Cat	Gpx8	ENSMUSP00000028610	ENSMUSP00000022282	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	Probable glutathione peroxidase 8; Belongs to the glutathione peroxidase family.	0.609
Gpx1	Cat	ENSMUSP00000081010	ENSMUSP00000028610	Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	0.547
Gpx1	Gpx2	ENSMUSP00000081010	ENSMUSP00000081012	Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown.	Glutathione peroxidase 2.	0.425
Gpx2	Cat	ENSMUSP00000081012	ENSMUSP00000028610	Glutathione peroxidase 2.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	0.504
Gpx2	Gpx1	ENSMUSP00000081012	ENSMUSP00000081010	Glutathione peroxidase 2.	Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown.	0.425
Gpx3	Cat	ENSMUSP00000081011	ENSMUSP00000028610	Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	0.513
Gpx5	Cat	ENSMUSP00000106117	ENSMUSP00000028610	Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	0.508
Gpx6	Cat	ENSMUSP00000004453	ENSMUSP00000028610	Glutathione peroxidase 6; Belongs to the glutathione peroxidase family.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	0.508
Gpx7	Cat	ENSMUSP00000030332	ENSMUSP00000028610	Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks (By similarity).	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	0.607
Gpx8	Cat	ENSMUSP00000022282	ENSMUSP00000028610	Probable glutathione peroxidase 8; Belongs to the glutathione peroxidase family.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	0.609