STRINGSTRING
Cstdc4 Cstdc4 Csta2 Csta2 Cst10 Cst10 Stfa3 Stfa3 Stfa2l1 Stfa2l1 Stfa1 Stfa1 Cstb Cstb Csta3 Csta3 Csta1 Csta1 Cstdc5 Cstdc5 Cstdc6 Cstdc6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cstdc4Cystatin domain-containing 4; Belongs to the cystatin family. (97 aa)
Csta2Cystatin A family member 2; Belongs to the cystatin family. (97 aa)
Cst10Cystatin 10; May play a role in the last steps of the chondrocyte differentiation pathway as an inducer of maturation. Induces chondrocyte calcification during endochondral ossification by playing a role in the transcriptional inhibition of ENPP1, a generator of pyrophosphate which inhibits calcification. Possibly impairs the binding of a transcription factor to the ENPP1 promoter. Unlike other cystatins, does not have thiol protease inhibitor activity. (148 aa)
Stfa3Stefin-3; This is an intracellular thiol proteinase inhibitor; Belongs to the cystatin family. (103 aa)
Stfa2l1Stefin-2; This is an intracellular thiol proteinase inhibitor. (103 aa)
Stfa1Stefin-1; This is an intracellular thiol proteinase inhibitor; Belongs to the cystatin family. (97 aa)
CstbCystatin-B; This is an intracellular thiol proteinase inhibitor. (98 aa)
Csta3Cystatin A family member 3. (97 aa)
Csta1Cystatin-A; This is an intracellular thiol proteinase inhibitor. Belongs to the cystatin family. (97 aa)
Cstdc5Cystatin domain-containing 5. (97 aa)
Cstdc6Cystatin domain-containing 6. (96 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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