STRINGSTRING
Igll1 Igll1 H2-Q10 H2-Q10 Trgc3 Trgc3 H2-M5 H2-M5 H2-M2 H2-M2 Sirpa Sirpa H2-DMb1 H2-DMb1 H2-T24 H2-T24 Gm11127 Gm11127 Iglc2 Iglc2 H2-T23 H2-T23 H2-T3 H2-T3 B2m B2m H2-Ob H2-Ob Hfe Hfe Sirpb1b Sirpb1b H2-M9 H2-M9 H2-Q4 H2-Q4 H2-T22 H2-T22 H2-Q2 H2-Q2 H2-M10.3 H2-M10.3 H2-Q1 H2-Q1 H2-Q7 H2-Q7 Mill1 Mill1 Sirpb1c Sirpb1c H2-M10.4 H2-M10.4 F830045P16Rik F830045P16Rik H2-Eb2 H2-Eb2 H2-M10.5 H2-M10.5 Tapbpl Tapbpl H2-Aa H2-Aa 2410137M14Rik 2410137M14Rik H2-DMb2 H2-DMb2 H2-M11 H2-M11 H2-Ab1 H2-Ab1 Gm7030 Gm7030 H2-M1 H2-M1 H2-M10.6 H2-M10.6 Azgp1 Azgp1 H2-DMa H2-DMa Gm8909 Gm8909 H2-M3 H2-M3 Cd1d1 Cd1d1 Mr1 Mr1 H2-M10.1 H2-M10.1 H2-Oa H2-Oa H2-K1 H2-K1 Tapbp Tapbp H2-M10.2 H2-M10.2 Fcgrt Fcgrt H2-Eb1 H2-Eb1 Mill2 Mill2 Sirpb1a Sirpb1a H2-D1 H2-D1 H2-Q6 H2-Q6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Igll1Immunoglobulin lambda-like polypeptide 1; Critical for B-cell development. (209 aa)
H2-Q10H-2 class I histocompatibility antigen, Q10 alpha chain; Involved in the presentation of foreign antigens to the immune system. (325 aa)
Trgc3T-cell receptor gamma chain C region C7.5. (172 aa)
H2-M5Histocompatibility 2, M region locus 5; Belongs to the MHC class I family. (348 aa)
H2-M2Histocompatibility 2, M region locus 2; Belongs to the MHC class I family. (343 aa)
SirpaTyrosine-protein phosphatase non-receptor type substrate 1; Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative re [...] (513 aa)
H2-DMb1Class II histocompatibility antigen, M beta 1 chain; Plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides; Belongs to the MHC class II family. (261 aa)
H2-T24Histocompatibility 2, T region locus 24; Belongs to the MHC class I family. (363 aa)
Gm11127Predicted gene 11127; Belongs to the MHC class I family. (374 aa)
Iglc2Ig lambda-2 chain C region. (104 aa)
H2-T23H-2 class I histocompatibility antigen, D-37 alpha chain; Involved in the presentation of foreign antigens to the immune system. (357 aa)
H2-T3H-2 class I histocompatibility antigen, TLA(B) alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family. (384 aa)
B2mBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. (119 aa)
H2-ObHistocompatibility 2, O region beta locus. (271 aa)
HfeHereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. (359 aa)
Sirpb1bSignal-regulatory protein beta 1B. (391 aa)
H2-M9Histocompatibility 2, M region locus 9; Belongs to the MHC class I family. (342 aa)
H2-Q4Histocompatibility 2, Q region locus 4; Belongs to the MHC class I family. (354 aa)
H2-T22Histocompatibility 2, T region locus 22; Belongs to the MHC class I family. (379 aa)
H2-Q2Histocompatibility 2, Q region locus 2; Belongs to the MHC class I family. (360 aa)
H2-M10.3Major histocompatibility complex class Ib M10.3; Belongs to the MHC class I family. (330 aa)
H2-Q1Histocompatibility 2, Q region locus 1; Belongs to the MHC class I family. (368 aa)
H2-Q7H-2 class I histocompatibility antigen, Q7 alpha chain; Involved in the presentation of foreign antigens to the immune system. (334 aa)
Mill1MHC I-like leukocyte 1; Belongs to the MHC class I family. (395 aa)
Sirpb1cSignal-regulatory protein beta 1C. (391 aa)
H2-M10.4Histocompatibility 2, M region locus 10.4; Belongs to the MHC class I family. (331 aa)
F830045P16RikRIKEN cDNA F830045P16 gene. (487 aa)
H2-Eb2Histocompatibility 2, class II antigen E beta2. (287 aa)
H2-M10.5Histocompatibility 2, M region locus 10.5; Belongs to the MHC class I family. (330 aa)
TapbplTapasin-related protein; Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). Expression seems to slow down and down-regulate MHC class I surface expression. (451 aa)
H2-AaH-2 class II histocompatibility antigen, A-B alpha chain. (256 aa)
2410137M14RikRIKEN cDNA 2410137M14 gene. (162 aa)
H2-DMb2Histocompatibility 2, class II, locus Mb2. (261 aa)
H2-M11Histocompatibility 2, M region locus 11; Belongs to the MHC class I family. (335 aa)
H2-Ab1H-2 class II histocompatibility antigen, A beta chain; Belongs to the MHC class II family. (265 aa)
Gm7030Predicted gene 7030; Belongs to the MHC class I family. (285 aa)
H2-M1Histocompatibility 2, M region locus 1; Belongs to the MHC class I family. (344 aa)
H2-M10.6Major histocompatibility complex class Ib M10.8; Belongs to the MHC class I family. (330 aa)
Azgp1Zinc-alpha-2-glycoprotein; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. (307 aa)
H2-DMaClass II histocompatibility antigen, M alpha chain; Plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides. (261 aa)
Gm8909Predicted gene 8909; Belongs to the MHC class I family. (368 aa)
H2-M3Histocompatibility 2, M region locus 3; Belongs to the MHC class I family. (336 aa)
Cd1d1Antigen-presenting glycoprotein CD1d1; Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T- cells. (336 aa)
Mr1Major histocompatibility complex class I-related gene protein; Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites (By similarity). Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent. (341 aa)
H2-M10.1Histocompatibility 2, M region locus 10.1; Belongs to the MHC class I family. (331 aa)
H2-OaHistocompatibility 2, O region alpha locus; Belongs to the MHC class II family. (250 aa)
H2-K1H-2 class I histocompatibility antigen, K-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family. (369 aa)
TapbpTapasin; Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading). (466 aa)
H2-M10.2Histocompatibility 2, M region locus 10.2; Belongs to the MHC class I family. (329 aa)
FcgrtIgG receptor FcRn large subunit p51; Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, [...] (365 aa)
H2-Eb1H-2 class II histocompatibility antigen, E-B beta chain; Belongs to the MHC class II family. (264 aa)
Mill2MHC I-like leukocyte 2 long form; Belongs to the MHC class I family. (355 aa)
Sirpb1aSignal-regulatory protein beta 1A. (391 aa)
H2-D1H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family. (362 aa)
H2-Q6H-2 class I histocompatibility antigen, Q8 alpha chain; Involved in the presentation of foreign antigens to the immune system. (326 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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