STRINGSTRING
Ms4a8a Ms4a8a Sspn Sspn Fam189b Fam189b Ms4a4b Ms4a4b Ms4a5 Ms4a5 Ms4a4c Ms4a4c Ms4a10 Ms4a10 Ms4a13 Ms4a13 Ms4a15 Ms4a15 Tmem176a Tmem176a Ms4a3 Ms4a3 Fam189a1 Fam189a1 Ms4a6b Ms4a6b Ms4a1 Ms4a1 Ms4a2 Ms4a2 Tmem176b Tmem176b Ms4a6c Ms4a6c Ms4a18 Ms4a18 Ms4a4a Ms4a4a Ms4a12 Ms4a12 Ms4a14 Ms4a14 Ms4a7 Ms4a7 Ms4a4d Ms4a4d Ms4a6d Ms4a6d Ms4a20 Ms4a20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ms4a8aMembrane-spanning 4-domains subfamily A member 8; May be involved in signal transduction as a component of a multimeric receptor complex. (290 aa)
SspnSarcospan; Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC (By similarity). (216 aa)
Fam189bProtein FAM189B; Belongs to the FAM189 family. (669 aa)
Ms4a4bMembrane-spanning 4-domains, subfamily A, member 4B. (226 aa)
Ms4a5Membrane-spanning 4-domains, subfamily A, member 5. (197 aa)
Ms4a4cMembrane-spanning 4-domains, subfamily A, member 4C. (226 aa)
Ms4a10Membrane-spanning 4-domains subfamily A member 10; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family. (267 aa)
Ms4a13Membrane-spanning 4-domains subfamily A member 13; May be involved in signal transduction as a component of a multimeric receptor complex. (203 aa)
Ms4a15Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family. (245 aa)
Tmem176aTransmembrane protein 176A. (244 aa)
Ms4a3Membrane-spanning 4-domains subfamily A member 3; Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP) (By similarity). (213 aa)
Fam189a1Protein FAM189A1; Belongs to the FAM189 family. (515 aa)
Ms4a6bMembrane-spanning 4-domains subfamily A member 6B; May be involved in signal transduction as a component of a multimeric receptor complex. (244 aa)
Ms4a1B-lymphocyte antigen CD20; B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. Belongs to the MS4A family. (291 aa)
Ms4a2High affinity immunoglobulin epsilon receptor subunit beta; High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor- bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy. Belongs to the MS4A family. (235 aa)
Tmem176bTransmembrane protein 176B; May play a role in the process of maturation of dendritic cells (By similarity). Required for the development of cerebellar granule cells. (263 aa)
Ms4a6cMembrane-spanning 4-domains subfamily A member 6C; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family. (217 aa)
Ms4a18Membrane-spanning 4-domains, subfamily A, member 18. (344 aa)
Ms4a4aMembrane-spanning 4-domains, subfamily A, member 4A. (236 aa)
Ms4a12Membrane-spanning 4-domains, subfamily A, member 12. (263 aa)
Ms4a14Membrane-spanning 4-domains, subfamily A, member 14. (1232 aa)
Ms4a7Membrane-spanning 4-domains, subfamily A, member 7. (267 aa)
Ms4a4dMembrane-spanning 4-domains subfamily A member 4D; May be involved in signal transduction as a component of a multimeric receptor complex. (225 aa)
Ms4a6dMembrane-spanning 4-domains subfamily A member 6D; May be involved in signal transduction as a component of a multimeric receptor complex. (247 aa)
Ms4a20Membrane-spanning 4-domains, subfamily A, member 20. (209 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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