STRINGSTRING
Zswim6 Zswim6 Zswim2 Zswim2 Zswim4 Zswim4 Zswim8 Zswim8 Zswim1 Zswim1 Zswim5 Zswim5 Map3k1 Map3k1 Zswim7 Zswim7 Zswim3 Zswim3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Zswim6Zinc finger SWIM domain-containing protein 6; involved in nervous system development, important for striatal morphology and motor regulation. (1207 aa)
Zswim2E3 ubiquitin-protein ligase Zswim2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes. (631 aa)
Zswim4Zinc finger SWIM domain-containing protein 4. (1101 aa)
Zswim8Zinc finger SWIM domain-containing protein 8. (1832 aa)
Zswim1Zinc finger SWIM domain-containing protein 1. (455 aa)
Zswim5Zinc finger SWIM domain-containing protein 5. (1188 aa)
Map3k1Mitogen-activated protein kinase kinase kinase 1; Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. (1493 aa)
Zswim7Zinc finger SWIM domain-containing protein 7; Involved in early stages of the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. (152 aa)
Zswim3Zinc finger SWIM domain-containing protein 3. (695 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.