(8 nodes) Metallocarboxypeptidase-like, propeptide network (Mus musculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cpb1	Carboxypeptidase B1 (Tissue). (415 aa)
	Cpa2	Carboxypeptidase A2. (417 aa)
	Cpa5	Carboxypeptidase A5. (436 aa)
	Cpa4	Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val; Belongs to the peptidase M14 family. (420 aa)
	Cpb2	Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin; Belongs to the peptidase M14 family. (422 aa)
	Cpa1	Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. (419 aa)
	Cpa6	Carboxypeptidase A6; May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine. (438 aa)
	Cpa3	Mast cell carboxypeptidase A. (417 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cpa1	Cpa2	ENSMUSP00000031806	ENSMUSP00000093771	Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.	Carboxypeptidase A2.	0.966
Cpa1	Cpa3	ENSMUSP00000031806	ENSMUSP00000001921	Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.	Mast cell carboxypeptidase A.	0.917
Cpa1	Cpb1	ENSMUSP00000031806	ENSMUSP00000011607	Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.	Carboxypeptidase B1 (Tissue).	0.999
Cpa2	Cpa1	ENSMUSP00000093771	ENSMUSP00000031806	Carboxypeptidase A2.	Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.	0.966
Cpa2	Cpa3	ENSMUSP00000093771	ENSMUSP00000001921	Carboxypeptidase A2.	Mast cell carboxypeptidase A.	0.917
Cpa2	Cpb1	ENSMUSP00000093771	ENSMUSP00000011607	Carboxypeptidase A2.	Carboxypeptidase B1 (Tissue).	0.654
Cpa3	Cpa1	ENSMUSP00000001921	ENSMUSP00000031806	Mast cell carboxypeptidase A.	Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.	0.917
Cpa3	Cpa2	ENSMUSP00000001921	ENSMUSP00000093771	Mast cell carboxypeptidase A.	Carboxypeptidase A2.	0.917
Cpb1	Cpa1	ENSMUSP00000011607	ENSMUSP00000031806	Carboxypeptidase B1 (Tissue).	Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.	0.999
Cpb1	Cpa2	ENSMUSP00000011607	ENSMUSP00000093771	Carboxypeptidase B1 (Tissue).	Carboxypeptidase A2.	0.654
Cpb1	Cpb2	ENSMUSP00000011607	ENSMUSP00000022576	Carboxypeptidase B1 (Tissue).	Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin; Belongs to the peptidase M14 family.	0.916
Cpb2	Cpb1	ENSMUSP00000022576	ENSMUSP00000011607	Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin; Belongs to the peptidase M14 family.	Carboxypeptidase B1 (Tissue).	0.916