| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Fxyd1 | Fxyd2 | ENSMUSP00000048460 | ENSMUSP00000035429 | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation- mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. | Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. | 0.916 |
| Fxyd1 | Fxyd3 | ENSMUSP00000048460 | ENSMUSP00000130245 | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation- mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (By similarity). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (By similarity); Belongs to the FXYD family. | 0.443 |
| Fxyd1 | Fxyd4 | ENSMUSP00000048460 | ENSMUSP00000005114 | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation- mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. | FXYD domain-containing ion transport regulator 4. | 0.963 |
| Fxyd1 | Fxyd5 | ENSMUSP00000048460 | ENSMUSP00000009831 | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation- mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. | FXYD domain-containing ion transport regulator 5; Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). | 0.615 |
| Fxyd1 | Fxyd7 | ENSMUSP00000048460 | ENSMUSP00000073555 | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation- mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. | FXYD domain-containing ion transport regulator 7. | 0.438 |
| Fxyd2 | Fxyd1 | ENSMUSP00000035429 | ENSMUSP00000048460 | Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation- mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. | 0.916 |
| Fxyd2 | Fxyd3 | ENSMUSP00000035429 | ENSMUSP00000130245 | Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (By similarity). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (By similarity); Belongs to the FXYD family. | 0.752 |
| Fxyd2 | Fxyd4 | ENSMUSP00000035429 | ENSMUSP00000005114 | Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. | FXYD domain-containing ion transport regulator 4. | 0.960 |
| Fxyd2 | Fxyd5 | ENSMUSP00000035429 | ENSMUSP00000009831 | Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. | FXYD domain-containing ion transport regulator 5; Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). | 0.623 |
| Fxyd2 | Fxyd7 | ENSMUSP00000035429 | ENSMUSP00000073555 | Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. | FXYD domain-containing ion transport regulator 7. | 0.692 |
| Fxyd3 | Fxyd1 | ENSMUSP00000130245 | ENSMUSP00000048460 | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (By similarity). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (By similarity); Belongs to the FXYD family. | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation- mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. | 0.443 |
| Fxyd3 | Fxyd2 | ENSMUSP00000130245 | ENSMUSP00000035429 | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (By similarity). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (By similarity); Belongs to the FXYD family. | Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. | 0.752 |
| Fxyd3 | Fxyd5 | ENSMUSP00000130245 | ENSMUSP00000009831 | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (By similarity). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (By similarity); Belongs to the FXYD family. | FXYD domain-containing ion transport regulator 5; Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). | 0.553 |
| Fxyd3 | Fxyd6 | ENSMUSP00000130245 | ENSMUSP00000083101 | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (By similarity). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (By similarity); Belongs to the FXYD family. | FXYD domain-containing ion transport regulator 6; Belongs to the FXYD family. | 0.435 |
| Fxyd3 | Fxyd7 | ENSMUSP00000130245 | ENSMUSP00000073555 | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (By similarity). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (By similarity); Belongs to the FXYD family. | FXYD domain-containing ion transport regulator 7. | 0.804 |
| Fxyd4 | Fxyd1 | ENSMUSP00000005114 | ENSMUSP00000048460 | FXYD domain-containing ion transport regulator 4. | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation- mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. | 0.963 |
| Fxyd4 | Fxyd2 | ENSMUSP00000005114 | ENSMUSP00000035429 | FXYD domain-containing ion transport regulator 4. | Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. | 0.960 |
| Fxyd4 | Fxyd5 | ENSMUSP00000005114 | ENSMUSP00000009831 | FXYD domain-containing ion transport regulator 4. | FXYD domain-containing ion transport regulator 5; Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). | 0.648 |
| Fxyd4 | Fxyd7 | ENSMUSP00000005114 | ENSMUSP00000073555 | FXYD domain-containing ion transport regulator 4. | FXYD domain-containing ion transport regulator 7. | 0.810 |
| Fxyd5 | Fxyd1 | ENSMUSP00000009831 | ENSMUSP00000048460 | FXYD domain-containing ion transport regulator 5; Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation- mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. | 0.615 |