STRINGSTRING
Klhdc1 Klhdc1 Klhdc2 Klhdc2 Lztr1 Lztr1 Klhdc4 Klhdc4 Atrnl1 Atrnl1 Megf8 Megf8 Rabepk Rabepk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Klhdc1Kelch domain-containing protein 1. (406 aa)
Klhdc2Kelch domain-containing protein 2; Represses CREB3-mediated transcription by interfering with CREB3-DNA binding. (406 aa)
Lztr1Leucine-zipper-like transcriptional regulator 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS). Is a negative regulator of RAS-MAPK signaling that acts by controlling Ras levels and decreasing Ras association with membranes. (837 aa)
Klhdc4Kelch domain-containing protein 4. (584 aa)
Atrnl1Attractin-like protein 1; May play a role in melanocortin signaling pathways that regulate energy homeostasis. (1378 aa)
Megf8Multiple epidermal growth factor-like domains protein 8; Acts as a negative regulator of hedgehog signaling. (2789 aa)
RabepkRab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport. (380 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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