STRINGSTRING
Krt90 Krt90 Krt86 Krt86 Krt83 Krt83 Krt82 Krt82 Krt2 Krt2 Krt71 Krt71 Krt5 Krt5 Krt76 Krt76 Krt78 Krt78 Gm5478 Gm5478 Krt7 Krt7 Krt80 Krt80 Krt87 Krt87 Krt77 Krt77 Krt84 Krt84 Krt6b Krt6b Gm5414 Gm5414 Krt73 Krt73 Krt6a Krt6a Krt72 Krt72 Krt81 Krt81 Krt1 Krt1 Krt75 Krt75 Krt8 Krt8 Krt79 Krt79 Krt4 Krt4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Krt90Keratin 90; Belongs to the intermediate filament family. (538 aa)
Krt86Keratin, type II cuticular Hb6; Belongs to the intermediate filament family. (486 aa)
Krt83Keratin 83; Belongs to the intermediate filament family. (479 aa)
Krt82Keratin, type II cuticular Hb2; Belongs to the intermediate filament family. (516 aa)
Krt2Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin. (707 aa)
Krt71Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. (524 aa)
Krt5Keratin, type II cytoskeletal 5. (580 aa)
Krt76Keratin, type II cytoskeletal 2 oral; Probably contributes to terminal cornification. (594 aa)
Krt78Keratin 78; Belongs to the intermediate filament family. (1068 aa)
Gm5478Predicted pseudogene 5478; Belongs to the intermediate filament family. (535 aa)
Krt7Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. (457 aa)
Krt80Keratin, type II cytoskeletal 80; Belongs to the intermediate filament family. (452 aa)
Krt87Keratin, type II cuticular 87; Belongs to the intermediate filament family. (495 aa)
Krt77Keratin, type II cytoskeletal 1b. (572 aa)
Krt84Keratin, type II cuticular Hb4; Belongs to the intermediate filament family. (603 aa)
Krt6bKeratin, type II cytoskeletal 6B; Belongs to the intermediate filament family. (554 aa)
Gm5414Type II keratin Kb14; Belongs to the intermediate filament family. (552 aa)
Krt73Keratin, type II cytoskeletal 73; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (By similarity). (539 aa)
Krt6aKeratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. (553 aa)
Krt72Keratin, type II cytoskeletal 72; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (By similarity). (520 aa)
Krt81Keratin, type II cuticular Hb1. (481 aa)
Krt1Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. (637 aa)
Krt75Keratin, type II cytoskeletal 75; Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle (By similarity). (551 aa)
Krt8Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle; Belongs to the intermediate filament family. (490 aa)
Krt79Keratin, type II cytoskeletal 79; Belongs to the intermediate filament family. (531 aa)
Krt4Keratin, type II cytoskeletal 4. (525 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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