RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...]

S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...]

RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...]

Protein TCL1B1; Belongs to the TCL1 family.

RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...]

Protein TCL1B4; Belongs to the TCL1 family.

Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity); Belongs to the TGF-beta family.

Growth/differentiation factor 9; Required for ovarian folliculogenesis; Belongs to the TGF-beta family.

Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity); Belongs to the TGF-beta family.

NACHT, LRR and PYD domains-containing protein 5; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.

Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity); Belongs to the TGF-beta family.

Nucleoplasmin-2; Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.

Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity); Belongs to the TGF-beta family.

Zygote arrest protein 1; Essential for female fertility. May play a role in the oocyte-to-embryo transition; Belongs to the ZAR1 family.

Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity); Belongs to the TGF-beta family.

Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation; Belongs to the ZP domain family. ZPC subfamily.

F-box and WD-40 domain protein 13.

Predicted gene 8926.

F-box and WD-40 domain protein 13.

Oocyte-secreted protein 3; Belongs to the PLAC1 family.

F-box and WD-40 domain protein 13.

Spermatogenesis associated glutamate (E)-rich protein 1.

F-box and WD-40 domain protein 13.

Spermatogenesis-associated glutamate (E)-rich protein 4A.

F-box and WD-40 domain protein 13.

Protein TCL1B3; Belongs to the TCL1 family.

F-box and WD-40 domain protein 13.

Protein TCL1B4; Belongs to the TCL1 family.

F-box and WD-40 domain protein 14.

Predicted gene 8926.

F-box and WD-40 domain protein 14.

NACHT, LRR and PYD domains-containing protein 9A; May be involved in inflammation; Belongs to the NLRP family.

F-box and WD-40 domain protein 14.

Oocyte-secreted protein 3; Belongs to the PLAC1 family.

F-box and WD-40 domain protein 14.

Spermatogenesis associated glutamate (E)-rich protein 1.

F-box and WD-40 domain protein 14.

Spermatogenesis-associated glutamate (E)-rich protein 4A.

F-box and WD-40 domain protein 14.

Protein TCL1B3; Belongs to the TCL1 family.