node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gpx1 | Gpx2 | ENSMUSP00000081010 | ENSMUSP00000081012 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | Glutathione peroxidase 2. | 0.425 |
Gpx1 | Gsr | ENSMUSP00000081010 | ENSMUSP00000033992 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. | 0.975 |
Gpx1 | Ins1 | ENSMUSP00000081010 | ENSMUSP00000049095 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | Insulin-1 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.732 |
Gpx1 | Ins2 | ENSMUSP00000081010 | ENSMUSP00000147425 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | Insulin-2 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.745 |
Gpx1 | Txn1 | ENSMUSP00000081010 | ENSMUSP00000030051 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] | 0.926 |
Gpx2 | Gpx1 | ENSMUSP00000081012 | ENSMUSP00000081010 | Glutathione peroxidase 2. | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | 0.425 |
Gpx2 | Gsr | ENSMUSP00000081012 | ENSMUSP00000033992 | Glutathione peroxidase 2. | Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. | 0.968 |
Gpx2 | Ins1 | ENSMUSP00000081012 | ENSMUSP00000049095 | Glutathione peroxidase 2. | Insulin-1 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.715 |
Gpx2 | Ins2 | ENSMUSP00000081012 | ENSMUSP00000147425 | Glutathione peroxidase 2. | Insulin-2 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.716 |
Gpx2 | Txn1 | ENSMUSP00000081012 | ENSMUSP00000030051 | Glutathione peroxidase 2. | Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] | 0.898 |
Gpx3 | Gsr | ENSMUSP00000081011 | ENSMUSP00000033992 | Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. | Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. | 0.965 |
Gpx3 | Ins1 | ENSMUSP00000081011 | ENSMUSP00000049095 | Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. | Insulin-1 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.710 |
Gpx3 | Ins2 | ENSMUSP00000081011 | ENSMUSP00000147425 | Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. | Insulin-2 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.726 |
Gpx3 | Pvalb | ENSMUSP00000081011 | ENSMUSP00000005860 | Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. | Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions; Belongs to the parvalbumin family. | 0.600 |
Gpx3 | Txn1 | ENSMUSP00000081011 | ENSMUSP00000030051 | Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. | Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] | 0.893 |
Gpx5 | Gsr | ENSMUSP00000106117 | ENSMUSP00000033992 | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. | 0.965 |
Gpx5 | Ins1 | ENSMUSP00000106117 | ENSMUSP00000049095 | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | Insulin-1 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.717 |
Gpx5 | Ins2 | ENSMUSP00000106117 | ENSMUSP00000147425 | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | Insulin-2 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.729 |
Gpx5 | Txn1 | ENSMUSP00000106117 | ENSMUSP00000030051 | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] | 0.891 |
Gpx6 | Gsr | ENSMUSP00000004453 | ENSMUSP00000033992 | Glutathione peroxidase 6; Belongs to the glutathione peroxidase family. | Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. | 0.965 |