(6 nodes) (2025) Ly49G, but not Ly49CI, is dispensable for diverse antigen-specific memory NK cell responses in H-2d and H-2b mice. network (Mus musculus)

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Your Input:
	Klra7	Killer cell lectin-like receptor 7; Receptor on natural killer (NK) cells for class I MHC. (280 aa)
	Klra1	T-cell surface glycoprotein YE1/48; Receptor on natural killer (NK) cells for H-2d alleles. Inhibits the activity of NK cells thus preventing cell lysis. (262 aa)
	Atp8a1	Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...] (1164 aa)
	Klra3	Killer cell lectin-like receptor 3; Receptor on natural killer (NK) cells for class I MHC. (266 aa)
	Klra9	Killer cell lectin-like receptor subfamily A, member 9. (266 aa)
	H2-D1	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family. (362 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atp8a1	H2-D1	ENSMUSP00000042215	ENSMUSP00000134570	Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...]	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.	0.465
Atp8a1	Klra1	ENSMUSP00000042215	ENSMUSP00000032288	Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...]	T-cell surface glycoprotein YE1/48; Receptor on natural killer (NK) cells for H-2d alleles. Inhibits the activity of NK cells thus preventing cell lysis.	0.441
Atp8a1	Klra3	ENSMUSP00000042215	ENSMUSP00000107629	Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...]	Killer cell lectin-like receptor 3; Receptor on natural killer (NK) cells for class I MHC.	0.501
Atp8a1	Klra7	ENSMUSP00000042215	ENSMUSP00000107644	Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...]	Killer cell lectin-like receptor 7; Receptor on natural killer (NK) cells for class I MHC.	0.478
H2-D1	Atp8a1	ENSMUSP00000134570	ENSMUSP00000042215	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.	Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...]	0.465
H2-D1	Klra1	ENSMUSP00000134570	ENSMUSP00000032288	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.	T-cell surface glycoprotein YE1/48; Receptor on natural killer (NK) cells for H-2d alleles. Inhibits the activity of NK cells thus preventing cell lysis.	0.978
H2-D1	Klra3	ENSMUSP00000134570	ENSMUSP00000107629	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.	Killer cell lectin-like receptor 3; Receptor on natural killer (NK) cells for class I MHC.	0.987
H2-D1	Klra7	ENSMUSP00000134570	ENSMUSP00000107644	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.	Killer cell lectin-like receptor 7; Receptor on natural killer (NK) cells for class I MHC.	0.955
H2-D1	Klra9	ENSMUSP00000134570	ENSMUSP00000107663	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.	Killer cell lectin-like receptor subfamily A, member 9.	0.966
Klra1	Atp8a1	ENSMUSP00000032288	ENSMUSP00000042215	T-cell surface glycoprotein YE1/48; Receptor on natural killer (NK) cells for H-2d alleles. Inhibits the activity of NK cells thus preventing cell lysis.	Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...]	0.441
Klra1	H2-D1	ENSMUSP00000032288	ENSMUSP00000134570	T-cell surface glycoprotein YE1/48; Receptor on natural killer (NK) cells for H-2d alleles. Inhibits the activity of NK cells thus preventing cell lysis.	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.	0.978
Klra1	Klra7	ENSMUSP00000032288	ENSMUSP00000107644	T-cell surface glycoprotein YE1/48; Receptor on natural killer (NK) cells for H-2d alleles. Inhibits the activity of NK cells thus preventing cell lysis.	Killer cell lectin-like receptor 7; Receptor on natural killer (NK) cells for class I MHC.	0.760
Klra3	Atp8a1	ENSMUSP00000107629	ENSMUSP00000042215	Killer cell lectin-like receptor 3; Receptor on natural killer (NK) cells for class I MHC.	Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...]	0.501
Klra3	H2-D1	ENSMUSP00000107629	ENSMUSP00000134570	Killer cell lectin-like receptor 3; Receptor on natural killer (NK) cells for class I MHC.	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.	0.987
Klra7	Atp8a1	ENSMUSP00000107644	ENSMUSP00000042215	Killer cell lectin-like receptor 7; Receptor on natural killer (NK) cells for class I MHC.	Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...]	0.478
Klra7	H2-D1	ENSMUSP00000107644	ENSMUSP00000134570	Killer cell lectin-like receptor 7; Receptor on natural killer (NK) cells for class I MHC.	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.	0.955
Klra7	Klra1	ENSMUSP00000107644	ENSMUSP00000032288	Killer cell lectin-like receptor 7; Receptor on natural killer (NK) cells for class I MHC.	T-cell surface glycoprotein YE1/48; Receptor on natural killer (NK) cells for H-2d alleles. Inhibits the activity of NK cells thus preventing cell lysis.	0.760
Klra7	Klra9	ENSMUSP00000107644	ENSMUSP00000107663	Killer cell lectin-like receptor 7; Receptor on natural killer (NK) cells for class I MHC.	Killer cell lectin-like receptor subfamily A, member 9.	0.566
Klra9	H2-D1	ENSMUSP00000107663	ENSMUSP00000134570	Killer cell lectin-like receptor subfamily A, member 9.	H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.	0.966
Klra9	Klra7	ENSMUSP00000107663	ENSMUSP00000107644	Killer cell lectin-like receptor subfamily A, member 9.	Killer cell lectin-like receptor 7; Receptor on natural killer (NK) cells for class I MHC.	0.566