(18 nodes) (1977) Genetic regulation of UDP-glucuronosyltransferase induction by polycyclic aromatic compounds in mice. Co-segregation with aryl hydrocarbon (benzo(alpha)pyrene) hydroxylase induction. network (Mus musculus)

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Your Input:
	Ugt2b36	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
	Ugt2b34	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (532 aa)
	Ugt2b1	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	Ugt2b35	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	Ugt2a3	UDP-glucuronosyltransferase 2A3; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. (534 aa)
	Ugt1a2	UDP-glucuronosyltransferase 1-2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. (533 aa)
	Ugt2b5	UDP-glucuronosyltransferase 2B17; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. (530 aa)
	Ugt2b38	UDP glucuronosyltransferase 2 family, polypeptide B38. (530 aa)
	Ugt1a1	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. (535 aa)
	Ugt1a9	UDP-glucuronosyltransferase 1-9; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. (528 aa)
	Ugt2b37	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
	Ugt2a2	UDP-glucuronosyltransferase 2A2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. (528 aa)
	Ugt1a5	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	Ugt1a6a	UDP-glucuronosyltransferase 1-6; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Conjugates small planar phenolic molecules such as 4- nitrophenol, 1-naphthol, and 4-methylumbelliferone. The bulky phenol 4- hydroxybiphenyl, androgens and estrogens are not substrates. 2- hydroxybiphenyl is an excellent substrate; Belongs to the UDP-glycosyltransferase family. (531 aa)
	Ugt1a6b	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (531 aa)
	Ugt1a8	UDP-glucuronosyltransferase 1-7C; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. (530 aa)
	Ugt1a10	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
	Ugt2a1	UDP-glucuronosyltransferase 2A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory epithelium. (528 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ugt1a1	Ugt1a2	ENSMUSP00000072803	ENSMUSP00000037258	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 1-2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	0.453
Ugt1a1	Ugt1a5	ENSMUSP00000072803	ENSMUSP00000095263	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.517
Ugt1a1	Ugt1a6a	ENSMUSP00000072803	ENSMUSP00000108759	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 1-6; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Conjugates small planar phenolic molecules such as 4- nitrophenol, 1-naphthol, and 4-methylumbelliferone. The bulky phenol 4- hydroxybiphenyl, androgens and estrogens are not substrates. 2- hydroxybiphenyl is an excellent substrate; Belongs to the UDP-glycosyltransferase family.	0.467
Ugt1a1	Ugt1a8	ENSMUSP00000072803	ENSMUSP00000108764	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 1-7C; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.	0.414
Ugt1a1	Ugt1a9	ENSMUSP00000072803	ENSMUSP00000073444	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 1-9; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	0.474
Ugt1a1	Ugt2a1	ENSMUSP00000072803	ENSMUSP00000114583	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 2A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory epithelium.	0.428
Ugt1a1	Ugt2a2	ENSMUSP00000072803	ENSMUSP00000078740	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 2A2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	0.423
Ugt1a1	Ugt2b1	ENSMUSP00000072803	ENSMUSP00000031183	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.529
Ugt1a1	Ugt2b34	ENSMUSP00000072803	ENSMUSP00000031181	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.507
Ugt1a1	Ugt2b35	ENSMUSP00000072803	ENSMUSP00000031186	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.520
Ugt1a1	Ugt2b36	ENSMUSP00000072803	ENSMUSP00000092233	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.529
Ugt1a1	Ugt2b37	ENSMUSP00000072803	ENSMUSP00000075255	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.508
Ugt1a1	Ugt2b38	ENSMUSP00000072803	ENSMUSP00000072598	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP glucuronosyltransferase 2 family, polypeptide B38.	0.479
Ugt1a1	Ugt2b5	ENSMUSP00000072803	ENSMUSP00000068282	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 2B17; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	0.533
Ugt1a2	Ugt1a1	ENSMUSP00000037258	ENSMUSP00000072803	UDP-glucuronosyltransferase 1-2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	0.453
Ugt1a2	Ugt1a5	ENSMUSP00000037258	ENSMUSP00000095263	UDP-glucuronosyltransferase 1-2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.450
Ugt1a2	Ugt1a6a	ENSMUSP00000037258	ENSMUSP00000108759	UDP-glucuronosyltransferase 1-2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 1-6; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Conjugates small planar phenolic molecules such as 4- nitrophenol, 1-naphthol, and 4-methylumbelliferone. The bulky phenol 4- hydroxybiphenyl, androgens and estrogens are not substrates. 2- hydroxybiphenyl is an excellent substrate; Belongs to the UDP-glycosyltransferase family.	0.437
Ugt1a2	Ugt1a8	ENSMUSP00000037258	ENSMUSP00000108764	UDP-glucuronosyltransferase 1-2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 1-7C; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.	0.414
Ugt1a2	Ugt1a9	ENSMUSP00000037258	ENSMUSP00000073444	UDP-glucuronosyltransferase 1-2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 1-9; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	0.432
Ugt1a2	Ugt2a1	ENSMUSP00000037258	ENSMUSP00000114583	UDP-glucuronosyltransferase 1-2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	UDP-glucuronosyltransferase 2A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory epithelium.	0.423