(129 nodes) Regulation of gliogenesis network (Mus pahari)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MGP_PahariEiJ_P0021571	annotation not available (277 aa)
	Mecp2	Methyl-CpG-binding protein 2 isoform X1. (504 aa)
	Igf1	Insulin-like growth factor I isoform X1. (166 aa)
	MGP_PahariEiJ_P0087773	annotation not available (91 aa)
	Zfp365	Protein ZNF365. (408 aa)
	Egr2	E3 SUMO-protein ligase EGR2 isoform X1. (470 aa)
	Nr2e1	Nuclear receptor subfamily 2 group E member 1. (385 aa)
	Hdac2	Histone deacetylase 1/2. (488 aa)
	Rb1	Retinoblastoma-associated protein. (924 aa)
	Prmt5	Protein arginine N-methyltransferase 5 isoform X1. (637 aa)
	Bmp4	Bone morphogenetic protein 4. (408 aa)
	Zfp488	PR domain zinc finger protein 8. (337 aa)
	Prkch	Novel protein kinase C eta type. (683 aa)
	Sox11	Transcription factor SOX11/12 (SOX group C). (395 aa)
	Id2	DNA-binding protein inhibitor ID-2. (134 aa)
	Mycn	N-myc proto-oncogene protein. (465 aa)
	Ski	Ski oncogene isoform X1. (727 aa)
	Hes5	Hairy and enhancer of split 5. (166 aa)
	Trp73	Tumor protein p73 isoform X1. (638 aa)
	Casz1	Zinc finger protein castor homolog 1 isoform X1. (1754 aa)
	Mtor	Serine/threonine-protein kinase mTOR. (2549 aa)
	Mfn2	Mitofusin 2. (757 aa)
	Tnfrsf1b	Tumor necrosis factor receptor superfamily member 1B. (474 aa)
	Lin28a	Protein lin-28 homolog A. (191 aa)
	Hdac1	Histone deacetylase 1/2. (482 aa)
	Kdm4a	[histone H3]-trimethyl-L-lysine9/36 demethylase. (1063 aa)
	Dab1	Disabled homolog 1 isoform X1. (555 aa)
	Cdkn2b	Cyclin-dependent kinase 4 inhibitor B. (130 aa)
	Dusp10	Dual specificity protein phosphatase 10. (483 aa)
	Gpr37l1	Prosaposin receptor GPR37L1. (481 aa)
	Cxcr4	C-X-C chemokine receptor type 4. (359 aa)
	Actr3	Actin-related protein 3. (418 aa)
	Serpine2	Glia-derived nexin isoform X1. (397 aa)
	Cers2	Ceramide synthase 2. (380 aa)
	Tlr2	Toll-like receptor 2. (784 aa)
	Prkci	Atypical protein kinase C iota type. (596 aa)
	E2f1	Transcription factor E2F1. (433 aa)
	Nkx2-2	Homeobox protein Nkx-2.2 isoform X1. (273 aa)
	Bmp2	Bone morphogenetic protein 2. (394 aa)
	Ptpra	Protein tyrosine phosphatase receptor type A. (829 aa)
	Il1b	Interleukin-1 beta isoform X1. (269 aa)
	Spint1	Kunitz-type protease inhibitor 1 isoform X1. (507 aa)
	Mdk	Midkine isoform X1. (140 aa)
	F2	Coagulation factor II (thrombin). (618 aa)
	Dlx2	Homeobox protein DLX-2. (332 aa)
	Dlx1	Homeobox protein DLX-1 isoform X1. (255 aa)
	Lrp2	Low-density lipoprotein receptor-related protein 2. (4660 aa)
	Notch1	Neurogenic locus notch homolog protein 1. (2531 aa)
	Vim	Vimentin. (466 aa)
	Flt1	Vascular endothelial growth factor receptor 1 isoform X1. (1333 aa)
	Ppp1cc	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit. (323 aa)
	Rnf10	RING finger protein 10 isoform X1. (805 aa)
	Bag1	BAG family molecular chaperone regulator 1. (219 aa)
	Ufl1	E3 UFM1-protein ligase 1 isoform X1. (792 aa)
	Plag1	Zinc finger protein PLAG1 isoform X1. (499 aa)
	Lyn	Tyrosine-protein kinase Lyn isoform X1. (512 aa)
	Sox8	Transcription factor SOX7/8/10/18 (SOX group E/F). (464 aa)
	Slc7a5	Solute carrier family 7 (L-type amino acid transporter), member 5. (512 aa)
	Il34	Interleukin-34 isoform X1. (235 aa)
	Kras	GTPase KRas isoform X1. (189 aa)
	Ntf3	Neurotrophin-3 isoform X1. (271 aa)
	Pparg	Peroxisome proliferator-activated receptor gamma isoform X1. (505 aa)
	Atoh1	Protein atonal homolog 1. (351 aa)
	Ezh2	Histone-lysine N-methyltransferase EZH2 isoform X1. (746 aa)
	Ptn	Pleiotrophin. (168 aa)
	Ptprz1	Receptor-type tyrosine-protein phosphatase zeta isoform X1. (2311 aa)
	Il6	Interleukin 6. (211 aa)
	Shh	Sonic hedgehog protein isoform X1. (437 aa)
	Rheb	Ras homolog enriched in brain. (184 aa)
	Vegfc	Vascular endothelial growth factor C/D. (415 aa)
	Nrg1	Pro-neuregulin-1, membrane-bound isoform isoform X1. (701 aa)
	Tgfb1	Transforming growth factor beta-1 isoform X1. (390 aa)
	Adcyap1	Pituitary adenylate cyclase-activating polypeptide isoform X1. (175 aa)
	Daam2	Disheveled-associated activator of morphogenesis 2. (1115 aa)
	Trem2	Triggering receptor expressed on myeloid cells 2 isoform X1. (249 aa)
	Lta	Lymphotoxin alpha (TNF superfamily, member 1). (202 aa)
	Tnf	Tumor necrosis factor superfamily, member 2. (235 aa)
	Tspo	Translocator protein. (169 aa)
	Sox10	Transcription factor SOX7/8/10/18 (SOX group E/F). (466 aa)
	Ptk2	Focal adhesion kinase 1 isoform X1. (1091 aa)
	Myc	Myc proto-oncogene protein. (454 aa)
	Enpp2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X1. (914 aa)
	Id4	DNA-binding protein inhibitor ID-4. (161 aa)
	Atxn1	Ataxin-1 isoform X1. (798 aa)
	Mbd1	methyl-CpG binding domain protein 1. (580 aa)
	Bin1	Myc box-dependent-interacting protein 1 isoform X1. (588 aa)
	Gfap	Glial fibrillary acidic protein isoform X1. (430 aa)
	Nr1d1	Nuclear receptor subfamily 1 group D member 1. (616 aa)
	Nog	Noggin. (232 aa)
	Tmem98	Transmembrane protein 98. (226 aa)
	Nf1	Neurofibromin 1. (826 aa)
	Aspa	Aspartoacylase. (312 aa)
	Trp53	Cellular tumor antigen p53 isoform X1. (416 aa)
	Ntn1	Netrin 1. (604 aa)
	Rnf112	RING finger protein 112 isoform X1. (655 aa)
	Gjc2	Gap junction gamma-2 protein. (440 aa)
	Nkx6-1	Homeobox protein Nkx-6.1. (365 aa)
	Gsx2	Homeobox protein GSH. (305 aa)
	Fgfr3	Fibroblast growth factor receptor 3 isoform X1. (802 aa)
	Lif	Leukemia inhibitory factor isoform X1. (202 aa)
	Nf2	Merlin isoform X1. (596 aa)
	Egfr	Epidermal growth factor receptor isoform X1. (1210 aa)
	Rtn4	Reticulon-4 isoform X1. (1167 aa)
	Olig2	Class B basic helix-loop-helix protein 1/6/7. (323 aa)
	Synj1	Synaptojanin-1 isoform X1. (1607 aa)
	Drd3	D(3) dopamine receptor isoform X1. (446 aa)
	Hes1	Hairy and enhancer of split 1. (281 aa)
	Etv5	ETS translocation variant 5. (528 aa)
	Il6st	Interleukin-6 receptor subunit beta. (45 aa)
	Tert	Telomerase reverse transcriptase isoform X1. (1125 aa)
	Ctnnb1	Catenin beta-1 isoform X1. (781 aa)
	Dag1	Dystroglycan 1. (893 aa)
	Trf	Serotransferrin. (697 aa)
	Lingo1	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein. (620 aa)
	Ldlr	Low-density lipoprotein receptor isoform X1. (861 aa)
	Pitx3	Paired-like homeodomain transcription factor 3. (302 aa)
	Il33	Interleukin 33. (265 aa)
	Prpf19	Pre-mRNA-processing factor 19 isoform X1. (523 aa)
	Rela	Transcription factor p65. (549 aa)
	Clcf1	Cardiotrophin-like cytokine factor 1 isoform X1. (225 aa)
	Ascl2	Achaete-scute complex protein. (263 aa)
	Nkx6-2	Homeobox protein Nkx-6.2. (277 aa)
	Tenm4	Teneurin-4 isoform X1. (2831 aa)
	Idh2	Isocitrate dehydrogenase [NADP], mitochondrial. (452 aa)
	Ntrk3	Neurotrophic tyrosine kinase, receptor type 3. (864 aa)
	Abcc8	ATP-binding cassette sub-family C member 8 isoform X1. (1588 aa)
	Atf5	Cyclic AMP-dependent transcription factor ATF-5. (282 aa)
	Sirt2	NAD-dependent protein deacetylase sirtuin-2 isoform X1. (389 aa)
	Dll3	Delta-like protein 3 isoform X1. (585 aa)

Your Current Organism:

Mus pahari

NCBI taxonomy Id: 10093
Other names: Coelomys parahi, M. pahari, shrew mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abcc8	Nkx2-2	MGP_PahariEiJ_P0016528	MGP_PahariEiJ_P0066046	ATP-binding cassette sub-family C member 8 isoform X1.	Homeobox protein Nkx-2.2 isoform X1.	0.467
Abcc8	Nkx6-1	MGP_PahariEiJ_P0016528	MGP_PahariEiJ_P0032509	ATP-binding cassette sub-family C member 8 isoform X1.	Homeobox protein Nkx-6.1.	0.545
Ascl2	Atoh1	MGP_PahariEiJ_P0020203	MGP_PahariEiJ_P0050198	Achaete-scute complex protein.	Protein atonal homolog 1.	0.483
Ascl2	Ctnnb1	MGP_PahariEiJ_P0020203	MGP_PahariEiJ_P0026281	Achaete-scute complex protein.	Catenin beta-1 isoform X1.	0.470
Ascl2	Hes1	MGP_PahariEiJ_P0020203	MGP_PahariEiJ_P0028559	Achaete-scute complex protein.	Hairy and enhancer of split 1.	0.509
Atoh1	Ascl2	MGP_PahariEiJ_P0050198	MGP_PahariEiJ_P0020203	Protein atonal homolog 1.	Achaete-scute complex protein.	0.483
Atoh1	Hes1	MGP_PahariEiJ_P0050198	MGP_PahariEiJ_P0028559	Protein atonal homolog 1.	Hairy and enhancer of split 1.	0.459
Atoh1	Hes5	MGP_PahariEiJ_P0050198	MGP_PahariEiJ_P0081322	Protein atonal homolog 1.	Hairy and enhancer of split 5.	0.503
Atoh1	Notch1	MGP_PahariEiJ_P0050198	MGP_PahariEiJ_P0061406	Protein atonal homolog 1.	Neurogenic locus notch homolog protein 1.	0.506
Atoh1	Shh	MGP_PahariEiJ_P0050198	MGP_PahariEiJ_P0048516	Protein atonal homolog 1.	Sonic hedgehog protein isoform X1.	0.584
Bin1	Ctnnb1	MGP_PahariEiJ_P0038840	MGP_PahariEiJ_P0026281	Myc box-dependent-interacting protein 1 isoform X1.	Catenin beta-1 isoform X1.	0.649
Bin1	Myc	MGP_PahariEiJ_P0038840	MGP_PahariEiJ_P0041674	Myc box-dependent-interacting protein 1 isoform X1.	Myc proto-oncogene protein.	0.965
Bin1	Synj1	MGP_PahariEiJ_P0038840	MGP_PahariEiJ_P0029599	Myc box-dependent-interacting protein 1 isoform X1.	Synaptojanin-1 isoform X1.	0.780
Bin1	Tnf	MGP_PahariEiJ_P0038840	MGP_PahariEiJ_P0044023	Myc box-dependent-interacting protein 1 isoform X1.	Tumor necrosis factor superfamily, member 2.	0.400
Bin1	Trem2	MGP_PahariEiJ_P0038840	MGP_PahariEiJ_P0044695	Myc box-dependent-interacting protein 1 isoform X1.	Triggering receptor expressed on myeloid cells 2 isoform X1.	0.557
Bmp2	Bmp4	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0084438	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.939
Bmp2	Ctnnb1	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0026281	Bone morphogenetic protein 2.	Catenin beta-1 isoform X1.	0.584
Bmp2	Igf1	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0088279	Bone morphogenetic protein 2.	Insulin-like growth factor I isoform X1.	0.562
Bmp2	Il1b	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0065523	Bone morphogenetic protein 2.	Interleukin-1 beta isoform X1.	0.423
Bmp2	Il6	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0048550	Bone morphogenetic protein 2.	Interleukin 6.	0.506