(26 nodes) Positive regulation of bone resorption network (Mus pahari)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	Egfr	Epidermal growth factor receptor isoform X1. (1210 aa)
	Tfrc	Transferrin receptor protein 1. (763 aa)
	Ahsg	Alpha-2-HS-glycoprotein isoform X1. (349 aa)
	Ptger4	Prostaglandin E2 receptor EP4 subtype. (514 aa)
	Trf	Serotransferrin. (697 aa)
	Ltbp3	Latent-transforming growth factor beta-binding protein 3 isoform X1. (1253 aa)
	Adam8	Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (824 aa)
	Tmem64	Transmembrane protein 64 isoform X1. (385 aa)
	Def8	Differentially expressed in FDCP 8 homolog isoform X1. (482 aa)
	Tnfsf11	Tumor necrosis factor ligand superfamily member 11 isoform X1. (316 aa)
	Dlk1	Protein delta homolog 1 isoform X1. (385 aa)
	Fcgr4	Low affinity immunoglobulin gamma Fc region receptor IV. (249 aa)
	Tnfrsf11a	Tumor necrosis factor receptor superfamily member 11A. (621 aa)
	Car2	Carbonic anhydrase 2 isoform X1. (260 aa)
	Src	Proto-oncogene tyrosine-protein kinase Src isoform X1. (541 aa)
	Fshb	Follitropin subunit beta. (130 aa)
	Lrp6	Low-density lipoprotein receptor-related protein 6 isoform X1. (1613 aa)
	Dcstamp	Dendritic cell-specific transmembrane protein isoform X1. (470 aa)
	Syk	Tyrosine-protein kinase SYK isoform X1. (629 aa)
	Mc4r	Melanocortin 4 receptor. (332 aa)
	Ppargc1b	Peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1. (1021 aa)
	Prkca	Protein kinase C alpha type isoform X1. (672 aa)
	Itgb3	Integrin beta 3. (787 aa)
	Plekhm1	Pleckstrin homology domain-containing family M member 1. (1062 aa)
	Idua	Alpha-L-iduronidase isoform X1. (643 aa)
	Spp1	Secreted phosphoprotein 1. (308 aa)

Your Current Organism:

Mus pahari

NCBI taxonomy Id: 10093
Other names: Coelomys parahi, M. pahari, shrew mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adam8	Itgb3	MGP_PahariEiJ_P0019776	MGP_PahariEiJ_P0037177	Disintegrin and metalloproteinase domain-containing protein 8 isoform X1.	Integrin beta 3.	0.770
Ahsg	Spp1	MGP_PahariEiJ_P0028434	MGP_PahariEiJ_P0032584	Alpha-2-HS-glycoprotein isoform X1.	Secreted phosphoprotein 1.	0.655
Ahsg	Trf	MGP_PahariEiJ_P0028434	MGP_PahariEiJ_P0025016	Alpha-2-HS-glycoprotein isoform X1.	Serotransferrin.	0.598
Car2	Tnfsf11	MGP_PahariEiJ_P0067971	MGP_PahariEiJ_P0085549	Carbonic anhydrase 2 isoform X1.	Tumor necrosis factor ligand superfamily member 11 isoform X1.	0.542
Dcstamp	Itgb3	MGP_PahariEiJ_P0041512	MGP_PahariEiJ_P0037177	Dendritic cell-specific transmembrane protein isoform X1.	Integrin beta 3.	0.410
Dcstamp	Tnfrsf11a	MGP_PahariEiJ_P0041512	MGP_PahariEiJ_P0074653	Dendritic cell-specific transmembrane protein isoform X1.	Tumor necrosis factor receptor superfamily member 11A.	0.407
Dcstamp	Tnfsf11	MGP_PahariEiJ_P0041512	MGP_PahariEiJ_P0085549	Dendritic cell-specific transmembrane protein isoform X1.	Tumor necrosis factor ligand superfamily member 11 isoform X1.	0.724
Egfr	Itgb3	MGP_PahariEiJ_P0030207	MGP_PahariEiJ_P0037177	Epidermal growth factor receptor isoform X1.	Integrin beta 3.	0.553
Egfr	Lrp6	MGP_PahariEiJ_P0030207	MGP_PahariEiJ_P0052798	Epidermal growth factor receptor isoform X1.	Low-density lipoprotein receptor-related protein 6 isoform X1.	0.495
Egfr	Prkca	MGP_PahariEiJ_P0030207	MGP_PahariEiJ_P0037376	Epidermal growth factor receptor isoform X1.	Protein kinase C alpha type isoform X1.	0.426
Egfr	Spp1	MGP_PahariEiJ_P0030207	MGP_PahariEiJ_P0032584	Epidermal growth factor receptor isoform X1.	Secreted phosphoprotein 1.	0.568
Egfr	Src	MGP_PahariEiJ_P0030207	MGP_PahariEiJ_P0066760	Epidermal growth factor receptor isoform X1.	Proto-oncogene tyrosine-protein kinase Src isoform X1.	0.993
Egfr	Tfrc	MGP_PahariEiJ_P0030207	MGP_PahariEiJ_P0028677	Epidermal growth factor receptor isoform X1.	Transferrin receptor protein 1.	0.663
Egfr	Tnfsf11	MGP_PahariEiJ_P0030207	MGP_PahariEiJ_P0085549	Epidermal growth factor receptor isoform X1.	Tumor necrosis factor ligand superfamily member 11 isoform X1.	0.557
Fcgr4	Syk	MGP_PahariEiJ_P0076359	MGP_PahariEiJ_P0040970	Low affinity immunoglobulin gamma Fc region receptor IV.	Tyrosine-protein kinase SYK isoform X1.	0.949
Itgb3	Adam8	MGP_PahariEiJ_P0037177	MGP_PahariEiJ_P0019776	Integrin beta 3.	Disintegrin and metalloproteinase domain-containing protein 8 isoform X1.	0.770
Itgb3	Dcstamp	MGP_PahariEiJ_P0037177	MGP_PahariEiJ_P0041512	Integrin beta 3.	Dendritic cell-specific transmembrane protein isoform X1.	0.410
Itgb3	Egfr	MGP_PahariEiJ_P0037177	MGP_PahariEiJ_P0030207	Integrin beta 3.	Epidermal growth factor receptor isoform X1.	0.553
Itgb3	Ltbp3	MGP_PahariEiJ_P0037177	MGP_PahariEiJ_P0020686	Integrin beta 3.	Latent-transforming growth factor beta-binding protein 3 isoform X1.	0.446
Itgb3	Prkca	MGP_PahariEiJ_P0037177	MGP_PahariEiJ_P0037376	Integrin beta 3.	Protein kinase C alpha type isoform X1.	0.923