(35 nodes) Regulation of astrocyte differentiation network (Mus pahari)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MGP_PahariEiJ_P0087773	annotation not available (91 aa)
	Dll3	Delta-like protein 3 isoform X1. (585 aa)
	Atf5	Cyclic AMP-dependent transcription factor ATF-5. (282 aa)
	Ntrk3	Neurotrophic tyrosine kinase, receptor type 3. (864 aa)
	Clcf1	Cardiotrophin-like cytokine factor 1 isoform X1. (225 aa)
	Prpf19	Pre-mRNA-processing factor 19 isoform X1. (523 aa)
	Ldlr	Low-density lipoprotein receptor isoform X1. (861 aa)
	Il6st	Interleukin-6 receptor subunit beta. (45 aa)
	Hes1	Hairy and enhancer of split 1. (281 aa)
	Lif	Leukemia inhibitory factor isoform X1. (202 aa)
	Fgfr3	Fibroblast growth factor receptor 3 isoform X1. (802 aa)
	Nf1	Neurofibromin 1. (826 aa)
	Nog	Noggin. (232 aa)
	Nr1d1	Nuclear receptor subfamily 1 group D member 1. (616 aa)
	Bin1	Myc box-dependent-interacting protein 1 isoform X1. (588 aa)
	Mbd1	methyl-CpG binding domain protein 1. (580 aa)
	Id4	DNA-binding protein inhibitor ID-4. (161 aa)
	Trem2	Triggering receptor expressed on myeloid cells 2 isoform X1. (249 aa)
	Shh	Sonic hedgehog protein isoform X1. (437 aa)
	Notch1	Neurogenic locus notch homolog protein 1. (2531 aa)
	F2	Coagulation factor II (thrombin). (618 aa)
	Il1b	Interleukin-1 beta isoform X1. (269 aa)
	Bmp2	Bone morphogenetic protein 2. (394 aa)
	Epha4	Ephrin type-A receptor 4 isoform X1. (986 aa)
	Serpine2	Glia-derived nexin isoform X1. (397 aa)
	Actr3	Actin-related protein 3. (418 aa)
	Cntn2	Contactin 2. (1040 aa)
	Gpr37l1	Prosaposin receptor GPR37L1. (481 aa)
	Dab1	Disabled homolog 1 isoform X1. (555 aa)
	Kdm4a	[histone H3]-trimethyl-L-lysine9/36 demethylase. (1063 aa)
	Hes5	Hairy and enhancer of split 5. (166 aa)
	Mycn	N-myc proto-oncogene protein. (465 aa)
	Id2	DNA-binding protein inhibitor ID-2. (134 aa)
	Nr2e1	Nuclear receptor subfamily 2 group E member 1. (385 aa)
	Mecp2	Methyl-CpG-binding protein 2 isoform X1. (504 aa)

Your Current Organism:

Mus pahari

NCBI taxonomy Id: 10093
Other names: Coelomys parahi, M. pahari, shrew mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bin1	Trem2	MGP_PahariEiJ_P0038840	MGP_PahariEiJ_P0044695	Myc box-dependent-interacting protein 1 isoform X1.	Triggering receptor expressed on myeloid cells 2 isoform X1.	0.557
Bmp2	Il1b	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0065523	Bone morphogenetic protein 2.	Interleukin-1 beta isoform X1.	0.423
Bmp2	Nog	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0035869	Bone morphogenetic protein 2.	Noggin.	0.995
Bmp2	Notch1	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0061406	Bone morphogenetic protein 2.	Neurogenic locus notch homolog protein 1.	0.429
Clcf1	Il6st	MGP_PahariEiJ_P0020483	MGP_PahariEiJ_P0027136	Cardiotrophin-like cytokine factor 1 isoform X1.	Interleukin-6 receptor subunit beta.	0.925
Clcf1	Lif	MGP_PahariEiJ_P0020483	MGP_PahariEiJ_P0030524	Cardiotrophin-like cytokine factor 1 isoform X1.	Leukemia inhibitory factor isoform X1.	0.424
Dab1	Ldlr	MGP_PahariEiJ_P0078366	MGP_PahariEiJ_P0022639	Disabled homolog 1 isoform X1.	Low-density lipoprotein receptor isoform X1.	0.718
Dab1	Notch1	MGP_PahariEiJ_P0078366	MGP_PahariEiJ_P0061406	Disabled homolog 1 isoform X1.	Neurogenic locus notch homolog protein 1.	0.430
Dll3	Hes1	MGP_PahariEiJ_P0015220	MGP_PahariEiJ_P0028559	Delta-like protein 3 isoform X1.	Hairy and enhancer of split 1.	0.525
Dll3	Hes5	MGP_PahariEiJ_P0015220	MGP_PahariEiJ_P0081322	Delta-like protein 3 isoform X1.	Hairy and enhancer of split 5.	0.650
Dll3	Notch1	MGP_PahariEiJ_P0015220	MGP_PahariEiJ_P0061406	Delta-like protein 3 isoform X1.	Neurogenic locus notch homolog protein 1.	0.997
Epha4	Fgfr3	MGP_PahariEiJ_P0073883	MGP_PahariEiJ_P0030782	Ephrin type-A receptor 4 isoform X1.	Fibroblast growth factor receptor 3 isoform X1.	0.564
F2	Il1b	MGP_PahariEiJ_P0064085	MGP_PahariEiJ_P0065523	Coagulation factor II (thrombin).	Interleukin-1 beta isoform X1.	0.572
F2	Serpine2	MGP_PahariEiJ_P0064085	MGP_PahariEiJ_P0073932	Coagulation factor II (thrombin).	Glia-derived nexin isoform X1.	0.965
Fgfr3	Epha4	MGP_PahariEiJ_P0030782	MGP_PahariEiJ_P0073883	Fibroblast growth factor receptor 3 isoform X1.	Ephrin type-A receptor 4 isoform X1.	0.564
Hes1	Dll3	MGP_PahariEiJ_P0028559	MGP_PahariEiJ_P0015220	Hairy and enhancer of split 1.	Delta-like protein 3 isoform X1.	0.525
Hes1	Hes5	MGP_PahariEiJ_P0028559	MGP_PahariEiJ_P0081322	Hairy and enhancer of split 1.	Hairy and enhancer of split 5.	0.911
Hes1	Notch1	MGP_PahariEiJ_P0028559	MGP_PahariEiJ_P0061406	Hairy and enhancer of split 1.	Neurogenic locus notch homolog protein 1.	0.769
Hes5	Dll3	MGP_PahariEiJ_P0081322	MGP_PahariEiJ_P0015220	Hairy and enhancer of split 5.	Delta-like protein 3 isoform X1.	0.650
Hes5	Hes1	MGP_PahariEiJ_P0081322	MGP_PahariEiJ_P0028559	Hairy and enhancer of split 5.	Hairy and enhancer of split 1.	0.911