(29 nodes) Regulation of SMAD protein signal transduction network (Mus pahari)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D130043K22Rik	Dyslexia-associated protein KIAA0319 homolog isoform X1. (1081 aa)
	Lrp1	Low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor). (4545 aa)
	Pbld2	Phenazine biosynthesis-like domain-containing protein. (288 aa)
	Nodal	Nodal homolog. (354 aa)
	Bmp4	Bone morphogenetic protein 4. (408 aa)
	Bmpr1a	Bone morphogenetic protein receptor type-1A. (532 aa)
	Tgfb3	Transforming growth factor beta-3. (412 aa)
	Tgfbr1	TGF-beta receptor type-1 isoform X1. (503 aa)
	Parp1	Poly [ADP-ribose] polymerase 1. (98 aa)
	Bmpr2	Bone morphogenetic protein receptor type-2. (1020 aa)
	Veph1	Ventricular zone-expressed PH domain-containing protein homolog 1 isoform X1. (833 aa)
	Wwtr1	WW domain-containing transcription regulator protein 1 isoform X1. (395 aa)
	Slc2a10	MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 10. (536 aa)
	Gdf5	Growth differentiation factor 5. (495 aa)
	Ovol2	Transcription factor Ovo-like 2 isoform X1. (274 aa)
	Bmp2	Bone morphogenetic protein 2. (394 aa)
	Nup93	Nuclear pore complex protein Nup93 isoform X1. (819 aa)
	Pparg	Peroxisome proliferator-activated receptor gamma isoform X1. (505 aa)
	Rbpms	RNA-binding protein with multiple splicing isoform X1. (220 aa)
	Tgfb1	Transforming growth factor beta-1 isoform X1. (390 aa)
	Ccn3	Insulin-like growth factor-binding protein 9. (351 aa)
	Bmp6	Bone morphogenetic protein 6 isoform X1. (507 aa)
	Ucma	Unique cartilage matrix-associated protein isoform X1. (138 aa)
	Tob1	Protein Tob/BTG. (363 aa)
	Sptbn1	Spectrin beta chain, non-erythrocytic 1 isoform X1. (2363 aa)
	Dab2	Disabled homolog 2 isoform X1. (766 aa)
	Jak2	Tyrosine-protein kinase JAK2. (1132 aa)
	Fam89b	Protein FAM89B isoform X1. (189 aa)
	Sh2b1	SH2B adapter protein 1 isoform X1. (756 aa)

Your Current Organism:

Mus pahari

NCBI taxonomy Id: 10093
Other names: Coelomys parahi, M. pahari, shrew mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bmp2	Bmp4	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0084438	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.939
Bmp2	Bmp6	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0040744	Bone morphogenetic protein 2.	Bone morphogenetic protein 6 isoform X1.	0.955
Bmp2	Bmpr1a	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0084334	Bone morphogenetic protein 2.	Bone morphogenetic protein receptor type-1A.	0.998
Bmp2	Bmpr2	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0073201	Bone morphogenetic protein 2.	Bone morphogenetic protein receptor type-2.	0.991
Bmp2	Gdf5	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0066540	Bone morphogenetic protein 2.	Growth differentiation factor 5.	0.534
Bmp2	Pparg	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0051763	Bone morphogenetic protein 2.	Peroxisome proliferator-activated receptor gamma isoform X1.	0.409
Bmp2	Tgfbr1	MGP_PahariEiJ_P0065816	MGP_PahariEiJ_P0077434	Bone morphogenetic protein 2.	TGF-beta receptor type-1 isoform X1.	0.690
Bmp4	Bmp2	MGP_PahariEiJ_P0084438	MGP_PahariEiJ_P0065816	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.939
Bmp4	Bmp6	MGP_PahariEiJ_P0084438	MGP_PahariEiJ_P0040744	Bone morphogenetic protein 4.	Bone morphogenetic protein 6 isoform X1.	0.967
Bmp4	Bmpr1a	MGP_PahariEiJ_P0084438	MGP_PahariEiJ_P0084334	Bone morphogenetic protein 4.	Bone morphogenetic protein receptor type-1A.	0.998
Bmp4	Bmpr2	MGP_PahariEiJ_P0084438	MGP_PahariEiJ_P0073201	Bone morphogenetic protein 4.	Bone morphogenetic protein receptor type-2.	0.996
Bmp4	Gdf5	MGP_PahariEiJ_P0084438	MGP_PahariEiJ_P0066540	Bone morphogenetic protein 4.	Growth differentiation factor 5.	0.434
Bmp4	Tgfbr1	MGP_PahariEiJ_P0084438	MGP_PahariEiJ_P0077434	Bone morphogenetic protein 4.	TGF-beta receptor type-1 isoform X1.	0.785
Bmp6	Bmp2	MGP_PahariEiJ_P0040744	MGP_PahariEiJ_P0065816	Bone morphogenetic protein 6 isoform X1.	Bone morphogenetic protein 2.	0.955
Bmp6	Bmp4	MGP_PahariEiJ_P0040744	MGP_PahariEiJ_P0084438	Bone morphogenetic protein 6 isoform X1.	Bone morphogenetic protein 4.	0.967
Bmp6	Bmpr1a	MGP_PahariEiJ_P0040744	MGP_PahariEiJ_P0084334	Bone morphogenetic protein 6 isoform X1.	Bone morphogenetic protein receptor type-1A.	0.992
Bmp6	Bmpr2	MGP_PahariEiJ_P0040744	MGP_PahariEiJ_P0073201	Bone morphogenetic protein 6 isoform X1.	Bone morphogenetic protein receptor type-2.	0.985
Bmp6	Tgfbr1	MGP_PahariEiJ_P0040744	MGP_PahariEiJ_P0077434	Bone morphogenetic protein 6 isoform X1.	TGF-beta receptor type-1 isoform X1.	0.525
Bmpr1a	Bmp2	MGP_PahariEiJ_P0084334	MGP_PahariEiJ_P0065816	Bone morphogenetic protein receptor type-1A.	Bone morphogenetic protein 2.	0.998
Bmpr1a	Bmp4	MGP_PahariEiJ_P0084334	MGP_PahariEiJ_P0084438	Bone morphogenetic protein receptor type-1A.	Bone morphogenetic protein 4.	0.998