(19 nodes) Mixed, incl. Cellular glucuronidation, and Ethanol binding network (Mus spretus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Agxt	Alanine-glyoxylate aminotransferase. (414 aa)
	Serpina3k	Serine (or cysteine) peptidase inhibitor, clade A, member 3K. (418 aa)
	Akr1c6	Aldo-keto reductase family 1, member C6. (323 aa)
	Comt	catechol-O-methyltransferase. (265 aa)
	Cyp2c70	Cytochrome P450, family 2, subfamily c, polypeptide 70. (489 aa)
	Adh1	Alcohol dehydrogenase 1 (class I). (375 aa)
	Adh4	Alcohol dehydrogenase 4 (class II), pi polypeptide. (377 aa)
	Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1. (529 aa)
	Ugt2b35	UDP glucuronosyltransferase 2 family, polypeptide B35. (534 aa)
	MGP_SPRETEiJ_P0071545	annotation not available (530 aa)
	MGP_SPRETEiJ_P0071546	annotation not available (530 aa)
	Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3. (534 aa)
	Ugt2a2	UDP glucuronosyltransferase 2 family, polypeptide A2. (528 aa)
	MGP_SPRETEiJ_P0081487	annotation not available (492 aa)
	Cyp2e1	Cytochrome P450, family 2, subfamily e, polypeptide 1. (493 aa)
	Ces1c	Carboxylesterase 1C. (554 aa)
	Ces2e	Carboxylesterase 2E. (559 aa)
	Ces2f	Carboxylesterase 2F. (561 aa)
	Ces2g	Carboxylesterase 2G. (560 aa)

Your Current Organism:

Mus spretus

NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adh1	Adh4	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0063177	Alcohol dehydrogenase 1 (class I).	Alcohol dehydrogenase 4 (class II), pi polypeptide.	0.801
Adh1	Comt	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0042652	Alcohol dehydrogenase 1 (class I).	catechol-O-methyltransferase.	0.847
Adh1	Cyp2e1	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0086477	Alcohol dehydrogenase 1 (class I).	Cytochrome P450, family 2, subfamily e, polypeptide 1.	0.951
Adh1	MGP_SPRETEiJ_P0071545	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0071545	Alcohol dehydrogenase 1 (class I).	annotation not available	0.810
Adh1	MGP_SPRETEiJ_P0071546	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0071546	Alcohol dehydrogenase 1 (class I).	annotation not available	0.810
Adh1	Ugt2a3	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0071549	Alcohol dehydrogenase 1 (class I).	UDP glucuronosyltransferase 2 family, polypeptide A3.	0.834
Adh1	Ugt2b1	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0071538	Alcohol dehydrogenase 1 (class I).	UDP glucuronosyltransferase 2 family, polypeptide B1.	0.672
Adh1	Ugt2b35	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0071540	Alcohol dehydrogenase 1 (class I).	UDP glucuronosyltransferase 2 family, polypeptide B35.	0.792
Adh4	Adh1	MGP_SPRETEiJ_P0063177	MGP_SPRETEiJ_P0063169	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Alcohol dehydrogenase 1 (class I).	0.801
Adh4	Akr1c6	MGP_SPRETEiJ_P0063177	MGP_SPRETEiJ_P0035142	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Aldo-keto reductase family 1, member C6.	0.411
Adh4	Comt	MGP_SPRETEiJ_P0063177	MGP_SPRETEiJ_P0042652	Alcohol dehydrogenase 4 (class II), pi polypeptide.	catechol-O-methyltransferase.	0.848
Adh4	Cyp2e1	MGP_SPRETEiJ_P0063177	MGP_SPRETEiJ_P0086477	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Cytochrome P450, family 2, subfamily e, polypeptide 1.	0.897
Adh4	MGP_SPRETEiJ_P0071545	MGP_SPRETEiJ_P0063177	MGP_SPRETEiJ_P0071545	Alcohol dehydrogenase 4 (class II), pi polypeptide.	annotation not available	0.799
Adh4	MGP_SPRETEiJ_P0071546	MGP_SPRETEiJ_P0063177	MGP_SPRETEiJ_P0071546	Alcohol dehydrogenase 4 (class II), pi polypeptide.	annotation not available	0.799
Adh4	Ugt2a2	MGP_SPRETEiJ_P0063177	MGP_SPRETEiJ_P0071551	Alcohol dehydrogenase 4 (class II), pi polypeptide.	UDP glucuronosyltransferase 2 family, polypeptide A2.	0.589
Adh4	Ugt2a3	MGP_SPRETEiJ_P0063177	MGP_SPRETEiJ_P0071549	Alcohol dehydrogenase 4 (class II), pi polypeptide.	UDP glucuronosyltransferase 2 family, polypeptide A3.	0.868
Adh4	Ugt2b1	MGP_SPRETEiJ_P0063177	MGP_SPRETEiJ_P0071538	Alcohol dehydrogenase 4 (class II), pi polypeptide.	UDP glucuronosyltransferase 2 family, polypeptide B1.	0.763
Adh4	Ugt2b35	MGP_SPRETEiJ_P0063177	MGP_SPRETEiJ_P0071540	Alcohol dehydrogenase 4 (class II), pi polypeptide.	UDP glucuronosyltransferase 2 family, polypeptide B35.	0.792
Agxt	Akr1c6	MGP_SPRETEiJ_P0020206	MGP_SPRETEiJ_P0035142	Alanine-glyoxylate aminotransferase.	Aldo-keto reductase family 1, member C6.	0.986
Agxt	Ces1c	MGP_SPRETEiJ_P0020206	MGP_SPRETEiJ_P0089033	Alanine-glyoxylate aminotransferase.	Carboxylesterase 1C.	0.981