(105 nodes) Mixed, incl. Amine ligand-binding receptors, and Heterotrimeric G-protein complex network (Mus spretus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Htr2b	5-hydroxytryptamine (serotonin) receptor 2B. (479 aa)
	Sag	S-antigen, retina and pineal gland (arrestin). (403 aa)
	Htr5b	5-hydroxytryptamine (serotonin) receptor 5B. (370 aa)
	Adora1	Adenosine A1 receptor. (326 aa)
	Olfr420	Olfactory receptor 420. (321 aa)
	Gnaz	Guanine nucleotide binding protein, alpha z subunit. (355 aa)
	Adora2a	Adenosine A2a receptor. (410 aa)
	Csnk1g2	Casein kinase 1, gamma 2. (442 aa)
	Gng7	Guanine nucleotide binding protein (G protein), gamma 7. (69 aa)
	Gna15	Guanine nucleotide binding protein, alpha 15. (374 aa)
	Gna11	Guanine nucleotide binding protein, alpha 11. (359 aa)
	Olfr785	Olfactory receptor 785. (312 aa)
	Olfr788	Olfactory receptor 788. (311 aa)
	Olfr789	Olfactory receptor 789. (312 aa)
	MGP_SPRETEiJ_P0027745	annotation not available (308 aa)
	Olfr323	Olfactory receptor 323. (323 aa)
	Olfr315	Olfactory receptor 315. (307 aa)
	Adora2b	Adenosine A2b receptor. (332 aa)
	Rcvrn	Recoverin. (202 aa)
	Arrb2	Arrestin, beta 2. (421 aa)
	Slc6a4	Solute carrier family 6 (neurotransmitter transporter, serotonin), member 4. (630 aa)
	Git1	GIT ArfGAP 1. (770 aa)
	Gngt2	Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2. (69 aa)
	Chrm3	Cholinergic receptor, muscarinic 3, cardiac. (589 aa)
	Gng4	Guanine nucleotide binding protein (G protein), gamma 4. (75 aa)
	Drd1	Dopamine receptor D1. (446 aa)
	Hrh2	Histamine receptor H2. (397 aa)
	Grk6	G protein-coupled receptor kinase 6. (560 aa)
	Htr1a	5-hydroxytryptamine (serotonin) receptor 1A. (421 aa)
	Olfr721-ps1	Olfactory receptor 721, pseudogene 1. (324 aa)
	Gng2	Guanine nucleotide binding protein (G protein), gamma 2. (71 aa)
	Ptger2	Prostaglandin E receptor 2 (subtype EP2). (362 aa)
	Htr2a	5-hydroxytryptamine (serotonin) receptor 2A. (471 aa)
	Gpr18	G protein-coupled receptor 18. (331 aa)
	Gpr183	G protein-coupled receptor 183. (357 aa)
	Ptger4	Prostaglandin E receptor 4 (subtype EP4). (513 aa)
	Drd3	Dopamine receptor D3. (478 aa)
	Htr1f	5-hydroxytryptamine (serotonin) receptor 1F. (366 aa)
	Gng13	Guanine nucleotide binding protein (G protein), gamma 13. (67 aa)
	Hrh4	Histamine receptor H4. (391 aa)
	Adrb2	Adrenergic receptor, beta 2. (418 aa)
	Htr4	5 hydroxytryptamine (serotonin) receptor 4. (388 aa)
	Gnal	Guanine nucleotide binding protein, alpha stimulating, olfactory type. (448 aa)
	Grk2	G protein-coupled receptor kinase 2. (689 aa)
	Plcb3	Phospholipase C, beta 3. (1234 aa)
	Chrm1	Cholinergic receptor, muscarinic 1, CNS. (460 aa)
	Gng3	Guanine nucleotide binding protein (G protein), gamma 3. (75 aa)
	Olfr1500	Olfactory receptor 1500. (311 aa)
	Gna14	Guanine nucleotide binding protein, alpha 14. (355 aa)
	Htr7	5-hydroxytryptamine (serotonin) receptor 7. (470 aa)
	Adra2a	Adrenergic receptor, alpha 2a. (465 aa)
	Adrb1	Adrenergic receptor, beta 1. (466 aa)
	Grk5	G protein-coupled receptor kinase 5. (590 aa)
	MGP_SPRETEiJ_P0054825	annotation not available (250 aa)
	Olfr1079	Olfactory receptor 1079. (315 aa)
	Chrm4	Cholinergic receptor, muscarinic 4. (479 aa)
	Chrm5	Cholinergic receptor, muscarinic 5. (532 aa)
	Adra2b	Adrenergic receptor, alpha 2b. (453 aa)
	Plcb1	Phospholipase C, beta 1. (1216 aa)
	Plcb4	Phospholipase C, beta 4. (1239 aa)
	Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus. (1133 aa)
	MGP_SPRETEiJ_P0058775	annotation not available (466 aa)
	Gnb4	Guanine nucleotide binding protein (G protein), beta 4. (340 aa)
	MGP_SPRETEiJ_P0062130	annotation not available (173 aa)
	Tmigd3	Transmembrane and immunoglobulin domain containing 3. (210 aa)
	MGP_SPRETEiJ_P0063388	annotation not available (68 aa)
	Ptger3	Prostaglandin E receptor 3 (subtype EP3). (366 aa)
	Cnr1	Cannabinoid receptor 1 (brain). (473 aa)
	Gng10	Guanine nucleotide binding protein (G protein), gamma 10. (68 aa)
	Cnr2	Cannabinoid receptor 2 (macrophage). (347 aa)
	Htr1d	5-hydroxytryptamine (serotonin) receptor 1D. (374 aa)
	Htr6	5-hydroxytryptamine (serotonin) receptor 6. (440 aa)
	MGP_SPRETEiJ_P0068880	annotation not available (108 aa)
	Gnai1	Guanine nucleotide binding protein (G protein), alpha inhibiting 1. (354 aa)
	Htr5a	5-hydroxytryptamine (serotonin) receptor 5A. (357 aa)
	MGP_SPRETEiJ_P0070336	annotation not available (95 aa)
	Adra2c	Adrenergic receptor, alpha 2c. (458 aa)
	Drd5	Dopamine receptor D5. (478 aa)
	Grk3	G protein-coupled receptor kinase 3. (688 aa)
	Gnb2	Guanine nucleotide binding protein (G protein), beta 2. (382 aa)
	Gng11	Guanine nucleotide binding protein (G protein), gamma 11. (73 aa)
	Gng12	Guanine nucleotide binding protein (G protein), gamma 12. (83 aa)
	Hrh1	Histamine receptor H1. (488 aa)
	Rho	Rhodopsin. (348 aa)
	Gnb3	Guanine nucleotide binding protein (G protein), beta 3. (340 aa)
	Gng8	Guanine nucleotide binding protein (G protein), gamma 8. (70 aa)
	Olfr303	Olfactory receptor 303. (319 aa)
	Arrb1	Arrestin, beta 1. (419 aa)
	Olfr513	Olfactory receptor 513. (311 aa)
	Drd4	Dopamine receptor D4. (387 aa)
	Grk1	G protein-coupled receptor kinase 1. (564 aa)
	Adrb3	Adrenergic receptor, beta 3. (404 aa)
	Mtnr1a	Melatonin receptor 1A. (353 aa)
	Ptger1	Prostaglandin E receptor 1 (subtype EP1). (405 aa)
	Gm5741	Predicted gene 5741. (72 aa)
	MGP_SPRETEiJ_P0089054	annotation not available (354 aa)
	MGP_SPRETEiJ_P0090349	annotation not available (358 aa)
	Htr3a	5-hydroxytryptamine (serotonin) receptor 3A. (489 aa)
	Htr3b	5-hydroxytryptamine (serotonin) receptor 3B. (437 aa)
	Drd2	Dopamine receptor D2. (444 aa)
	Ankk1	Ankyrin repeat and kinase domain containing 1. (745 aa)
	Htr1b	5-hydroxytryptamine (serotonin) receptor 1B. (386 aa)
	Gnai2	Guanine nucleotide binding protein (G protein), alpha inhibiting 2. (355 aa)
	Gpr50	G-protein-coupled receptor 50. (591 aa)
	Htr2c	5-hydroxytryptamine (serotonin) receptor 2C. (459 aa)

Your Current Organism:

Mus spretus

NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adora1	Adora2a	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0024551	Adenosine A1 receptor.	Adenosine A2a receptor.	0.955
Adora1	Adora2b	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0028561	Adenosine A1 receptor.	Adenosine A2b receptor.	0.785
Adora1	Adra2b	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0056549	Adenosine A1 receptor.	Adrenergic receptor, alpha 2b.	0.406
Adora1	Adra2c	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0070384	Adenosine A1 receptor.	Adrenergic receptor, alpha 2c.	0.414
Adora1	Adrb2	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0048838	Adenosine A1 receptor.	Adrenergic receptor, beta 2.	0.586
Adora1	Drd1	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0036021	Adenosine A1 receptor.	Dopamine receptor D1.	0.716
Adora1	Drd2	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0091341	Adenosine A1 receptor.	Dopamine receptor D2.	0.584
Adora1	Gnai1	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0069365	Adenosine A1 receptor.	Guanine nucleotide binding protein (G protein), alpha inhibiting 1.	0.962
Adora1	Gnai2	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0093441	Adenosine A1 receptor.	Guanine nucleotide binding protein (G protein), alpha inhibiting 2.	0.993
Adora1	Gnaz	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0024535	Adenosine A1 receptor.	Guanine nucleotide binding protein, alpha z subunit.	0.426
Adora1	Gnb2	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0074327	Adenosine A1 receptor.	Guanine nucleotide binding protein (G protein), beta 2.	0.458
Adora1	Gnb4	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0059504	Adenosine A1 receptor.	Guanine nucleotide binding protein (G protein), beta 4.	0.549
Adora1	Gng2	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0037386	Adenosine A1 receptor.	Guanine nucleotide binding protein (G protein), gamma 2.	0.570
Adora1	MGP_SPRETEiJ_P0062130	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0062130	Adenosine A1 receptor.	annotation not available	0.950
Adora1	MGP_SPRETEiJ_P0068880	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0068880	Adenosine A1 receptor.	annotation not available	0.549
Adora1	MGP_SPRETEiJ_P0089054	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0089054	Adenosine A1 receptor.	annotation not available	0.761
Adora1	Tmigd3	MGP_SPRETEiJ_P0020989	MGP_SPRETEiJ_P0062133	Adenosine A1 receptor.	Transmembrane and immunoglobulin domain containing 3.	0.890
Adora2a	Adora1	MGP_SPRETEiJ_P0024551	MGP_SPRETEiJ_P0020989	Adenosine A2a receptor.	Adenosine A1 receptor.	0.955
Adora2a	Adora2b	MGP_SPRETEiJ_P0024551	MGP_SPRETEiJ_P0028561	Adenosine A2a receptor.	Adenosine A2b receptor.	0.960
Adora2a	Adra2b	MGP_SPRETEiJ_P0024551	MGP_SPRETEiJ_P0056549	Adenosine A2a receptor.	Adrenergic receptor, alpha 2b.	0.465