(88 nodes) Gap junction network (Mus spretus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MGP_SPRETEiJ_P0057391	annotation not available (69 aa)
	Gja6	Gap junction protein, alpha 6. (283 aa)
	Htr2c	5-hydroxytryptamine (serotonin) receptor 2C. (459 aa)
	Eras	ES cell-expressed Ras. (227 aa)
	Gnai2	Guanine nucleotide binding protein (G protein), alpha inhibiting 2. (355 aa)
	Map2k1	Mitogen-activated protein kinase kinase 1. (393 aa)
	Map2k5	Mitogen-activated protein kinase kinase 5. (448 aa)
	Drd2	Dopamine receptor D2. (444 aa)
	Pdgfd	Platelet-derived growth factor, D polypeptide. (370 aa)
	Gucy1a2	Guanylate cyclase 1, soluble, alpha 2. (730 aa)
	Tubb3	Tubulin, beta 3 class III. (450 aa)
	Rrad	Ras-related associated with diabetes. (307 aa)
	Adcy7	Adenylate cyclase 7. (1104 aa)
	Prkaca	Protein kinase, cAMP dependent, catalytic, alpha. (351 aa)
	Hras	Harvey rat sarcoma virus oncogene. (189 aa)
	Mapk3	Mitogen-activated protein kinase 3. (380 aa)
	Prkcb	Protein kinase C, beta. (673 aa)
	Grm5	Glutamate receptor, metabotropic 5. (1203 aa)
	Tjp1	Tight junction protein 1. (1744 aa)
	Prkcg	Protein kinase C, gamma. (697 aa)
	Itpr2	Inositol 1,4,5-triphosphate receptor 2. (2701 aa)
	MGP_SPRETEiJ_P0080095	annotation not available (450 aa)
	Kras	Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	MGP_SPRETEiJ_P0079372	annotation not available (450 aa)
	Tuba8	Tubulin, alpha 8. (449 aa)
	Raf1	V-raf-leukemia viral oncogene 1. (648 aa)
	Itpr1	Inositol 1,4,5-trisphosphate receptor 1. (2749 aa)
	Pdgfa	Platelet derived growth factor, alpha. (211 aa)
	Prkg2	Protein kinase, cGMP-dependent, type II. (762 aa)
	Pdgfra	Platelet derived growth factor receptor, alpha polypeptide. (1089 aa)
	Gnai1	Guanine nucleotide binding protein (G protein), alpha inhibiting 1. (354 aa)
	Gem	GTP binding protein (gene overexpressed in skeletal muscle). (295 aa)
	Prkacb	Protein kinase, cAMP dependent, catalytic, beta. (398 aa)
	Tuba4a	Tubulin, alpha 4A. (448 aa)
	Htr2b	5-hydroxytryptamine (serotonin) receptor 2B. (479 aa)
	Grm1	Glutamate receptor, metabotropic 1. (1199 aa)
	Gja1	Gap junction protein, alpha 1. (382 aa)
	Cdk1	Cyclin-dependent kinase 1. (297 aa)
	Map2k2	Mitogen-activated protein kinase kinase 2. (401 aa)
	Gna11	Guanine nucleotide binding protein, alpha 11. (359 aa)
	Adcy1	Adenylate cyclase 1. (1118 aa)
	Egfr	Epidermal growth factor receptor. (1210 aa)
	Mapk7	Mitogen-activated protein kinase 7. (802 aa)
	Prkca	Protein kinase C, alpha. (672 aa)
	Grb2	Growth factor receptor bound protein 2. (217 aa)
	Csnk1d	Casein kinase 1, delta. (415 aa)
	Adcy3	Adenylate cyclase 3. (1145 aa)
	Ptrhd1	peptidyl-tRNA hydrolase domain containing 1. (140 aa)
	MGP_SPRETEiJ_P0033722	annotation not available (455 aa)
	MGP_SPRETEiJ_P0033723	annotation not available (455 aa)
	Sos2	SOS Ras/Rho guanine nucleotide exchange factor 2. (1333 aa)
	Tubal3	Tubulin, alpha-like 3. (446 aa)
	MGP_SPRETEiJ_P0035677	annotation not available (145 aa)
	Drd1	Dopamine receptor D1. (446 aa)
	Adcy2	Adenylate cyclase 2. (1095 aa)
	Gucy1b2	Guanylate cyclase 1, soluble, beta 2. (809 aa)
	Htr2a	5-hydroxytryptamine (serotonin) receptor 2A. (471 aa)
	Adcy8	Adenylate cyclase 8. (1249 aa)
	Pdgfb	Platelet derived growth factor, B polypeptide. (241 aa)
	Adcy6	Adenylate cyclase 6. (1168 aa)
	Adcy9	Adenylate cyclase 9. (1353 aa)
	Mapk1	Mitogen-activated protein kinase 1. (358 aa)
	Adcy5	Adenylate cyclase 5. (1265 aa)
	Itpr3	Inositol 1,4,5-triphosphate receptor 3. (2670 aa)
	Tubb5	Tubulin, beta 5 class I. (444 aa)
	Tubb4a	Tubulin, beta 4A class IVA. (444 aa)
	Sos1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1319 aa)
	Map3k2	Mitogen-activated protein kinase kinase kinase 2. (619 aa)
	Pdgfrb	Platelet derived growth factor receptor, beta polypeptide. (1103 aa)
	Tubb6	Tubulin, beta 6 class V. (447 aa)
	Plcb3	Phospholipase C, beta 3. (1234 aa)
	Gnaq	Guanine nucleotide binding protein, alpha q polypeptide. (359 aa)
	Prkg1	Protein kinase, cGMP-dependent, type I. (686 aa)
	Adrb1	Adrenergic receptor, beta 1. (466 aa)
	MGP_SPRETEiJ_P0052074	annotation not available (294 aa)
	Gjd2	Gap junction protein, delta 2. (321 aa)
	Plcb2	Phospholipase C, beta 2. (1181 aa)
	Plcb1	Phospholipase C, beta 1. (1216 aa)
	Plcb4	Phospholipase C, beta 4. (1239 aa)
	Src	Rous sarcoma oncogene. (541 aa)
	Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus. (1133 aa)
	Tubb1	Tubulin, beta 1 class VI. (451 aa)
	Gucy1b1	Guanylate cyclase 1, soluble, beta 1. (620 aa)
	Gucy1a1	Guanylate cyclase 1, soluble, alpha 1. (691 aa)
	Csde1	Cold shock domain containing E1, RNA binding. (798 aa)
	Nras	Neuroblastoma ras oncogene. (189 aa)
	Gnai3	Guanine nucleotide binding protein (G protein), alpha inhibiting 3. (354 aa)
	Egf	Epidermal growth factor. (1214 aa)

Your Current Organism:

Mus spretus

NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adcy1	Adcy2	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0036491	Adenylate cyclase 1.	Adenylate cyclase 2.	0.568
Adcy1	Adcy5	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0043297	Adenylate cyclase 1.	Adenylate cyclase 5.	0.562
Adcy1	Adcy6	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0041527	Adenylate cyclase 1.	Adenylate cyclase 6.	0.562
Adcy1	Adcy7	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0088964	Adenylate cyclase 1.	Adenylate cyclase 7.	0.589
Adcy1	Adcy9	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0042010	Adenylate cyclase 1.	Adenylate cyclase 9.	0.700
Adcy1	Gnai1	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0069365	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting 1.	0.911
Adcy1	Gnai2	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0093441	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting 2.	0.888
Adcy1	Gnai3	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0062299	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting 3.	0.776
Adcy1	Gnas	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0058692	Adenylate cyclase 1.	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus.	0.976
Adcy1	Htr2a	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0039124	Adenylate cyclase 1.	5-hydroxytryptamine (serotonin) receptor 2A.	0.620
Adcy1	Htr2c	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0096719	Adenylate cyclase 1.	5-hydroxytryptamine (serotonin) receptor 2C.	0.622
Adcy1	Prkaca	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0088698	Adenylate cyclase 1.	Protein kinase, cAMP dependent, catalytic, alpha.	0.937
Adcy1	Prkacb	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0063416	Adenylate cyclase 1.	Protein kinase, cAMP dependent, catalytic, beta.	0.959
Adcy1	Prkca	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0032095	Adenylate cyclase 1.	Protein kinase C, alpha.	0.858
Adcy1	Prkcb	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0085371	Adenylate cyclase 1.	Protein kinase C, beta.	0.941
Adcy1	Prkcg	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0080297	Adenylate cyclase 1.	Protein kinase C, gamma.	0.866
Adcy1	Prkg1	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0050550	Adenylate cyclase 1.	Protein kinase, cGMP-dependent, type I.	0.840
Adcy1	Prkg2	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0071903	Adenylate cyclase 1.	Protein kinase, cGMP-dependent, type II.	0.507
Adcy1	Ptrhd1	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0033300	Adenylate cyclase 1.	peptidyl-tRNA hydrolase domain containing 1.	0.587
Adcy2	Adcy1	MGP_SPRETEiJ_P0036491	MGP_SPRETEiJ_P0026987	Adenylate cyclase 2.	Adenylate cyclase 1.	0.568