STRINGSTRING
Plcg2 Plcg2 Map2k1 Map2k1 Pik3cb Pik3cb Eras Eras Ikbkg Ikbkg Btk Btk Map2k2 Map2k2 MGP_SPRETEiJ_P0023987 MGP_SPRETEiJ_P0023987 Cr2 Cr2 Akt3 Akt3 Fcgr2b Fcgr2b Inpp5d Inpp5d Dapp1 Dapp1 Ppp3ca Ppp3ca Nfkb1 Nfkb1 Vav3 Vav3 Nras Nras Csde1 Csde1 Pik3ca Pik3ca Nfatc2 Nfatc2 MGP_SPRETEiJ_P0063342 MGP_SPRETEiJ_P0063342 Vav2 Vav2 Chuk Chuk Pik3ap1 Pik3ap1 Blnk Blnk Rela Rela Nfatc1 Nfatc1 Malt1 Malt1 Sos1 Sos1 Rasgrp3 Rasgrp3 Vav1 Vav1 Nfkbie Nfkbie Gsk3b Gsk3b Mapk1 Mapk1 MGP_SPRETEiJ_P0042320 MGP_SPRETEiJ_P0042320 Rac2 Rac2 Ppp3cc Ppp3cc Ppp3cb Ppp3cb Pik3r1 Pik3r1 Syk Syk Akt1 Akt1 Fos Fos Sos2 Sos2 Nfkbia Nfkbia Rac3 Rac3 Grb2 Grb2 MGP_SPRETEiJ_P0032003 MGP_SPRETEiJ_P0032003 Ppp3r1 Ppp3r1 Card11 Card11 Ppp3r2 Ppp3r2 Cd72 Cd72 Lyn Lyn Pik3cd Pik3cd MGP_SPRETEiJ_P0066259 MGP_SPRETEiJ_P0066259 Jun Jun Rac1 Rac1 Raf1 Raf1 Ptpn6 Ptpn6 Kras Kras MGP_SPRETEiJ_P0080379 MGP_SPRETEiJ_P0080379 Lilra5 Lilra5 Cd79a Cd79a Akt2 Akt2 Nfkbib Nfkbib Cd22 Cd22 Inppl1 Inppl1 Prkcb Prkcb Cd19 Cd19 Mapk3 Mapk3 Ifitm2 Ifitm2 Hras Hras Cd81 Cd81 Ikbkb Ikbkb Pik3r2 Pik3r2 Nfatc3 Nfatc3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Plcg2Phospholipase C, gamma 2. (1265 aa)
Map2k1Mitogen-activated protein kinase kinase 1. (393 aa)
Pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta. (1064 aa)
ErasES cell-expressed Ras. (227 aa)
IkbkgInhibitor of kappaB kinase gamma. (430 aa)
BtkBruton agammaglobulinemia tyrosine kinase. (659 aa)
Map2k2Mitogen-activated protein kinase kinase 2. (401 aa)
MGP_SPRETEiJ_P0023987annotation not available (167 aa)
Cr2Complement receptor 2. (1032 aa)
Akt3Thymoma viral proto-oncogene 3. (479 aa)
Fcgr2bFc receptor, IgG, low affinity IIb. (340 aa)
Inpp5dInositol polyphosphate-5-phosphatase D. (1191 aa)
Dapp1Dual adaptor for phosphotyrosine and 3-phosphoinositides 1. (239 aa)
Ppp3caProtein phosphatase 3, catalytic subunit, alpha isoform. (521 aa)
Nfkb1Nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105. (971 aa)
Vav3Vav 3 oncogene. (847 aa)
NrasNeuroblastoma ras oncogene. (189 aa)
Csde1Cold shock domain containing E1, RNA binding. (798 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha. (1068 aa)
Nfatc2Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2. (927 aa)
MGP_SPRETEiJ_P0063342annotation not available (143 aa)
Vav2Vav 2 oncogene. (868 aa)
ChukConserved helix-loop-helix ubiquitous kinase. (745 aa)
Pik3ap1Phosphoinositide-3-kinase adaptor protein 1. (811 aa)
BlnkB cell linker. (457 aa)
RelaV-rel reticuloendotheliosis viral oncogene homolog A (avian). (549 aa)
Nfatc1Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1. (939 aa)
Malt1MALT1 paracaspase. (821 aa)
Sos1SOS Ras/Rac guanine nucleotide exchange factor 1. (1319 aa)
Rasgrp3RAS, guanyl releasing protein 3. (691 aa)
Vav1Vav 1 oncogene. (688 aa)
NfkbieNuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon. (364 aa)
Gsk3bGlycogen synthase kinase 3 beta. (433 aa)
Mapk1Mitogen-activated protein kinase 1. (358 aa)
MGP_SPRETEiJ_P0042320annotation not available (81 aa)
Rac2Rac family small GTPase 2. (192 aa)
Ppp3ccProtein phosphatase 3, catalytic subunit, gamma isoform. (513 aa)
Ppp3cbProtein phosphatase 3, catalytic subunit, beta isoform. (525 aa)
Pik3r1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SykSpleen tyrosine kinase. (629 aa)
Akt1Thymoma viral proto-oncogene 1. (480 aa)
FosFBJ osteosarcoma oncogene. (380 aa)
Sos2SOS Ras/Rho guanine nucleotide exchange factor 2. (1333 aa)
NfkbiaNuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha. (314 aa)
Rac3Rac family small GTPase 3. (192 aa)
Grb2Growth factor receptor bound protein 2. (217 aa)
MGP_SPRETEiJ_P0032003annotation not available (288 aa)
Ppp3r1Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I). (170 aa)
Card11Caspase recruitment domain family, member 11. (1154 aa)
Ppp3r2Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II). (179 aa)
Cd72CD72 antigen. (361 aa)
LynLYN proto-oncogene, Src family tyrosine kinase. (502 aa)
Pik3cdPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta. (1047 aa)
MGP_SPRETEiJ_P0066259annotation not available (461 aa)
JunJun proto-oncogene. (334 aa)
Rac1Rac family small GTPase 1. (192 aa)
Raf1V-raf-leukemia viral oncogene 1. (648 aa)
Ptpn6Protein tyrosine phosphatase, non-receptor type 6. (597 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (189 aa)
MGP_SPRETEiJ_P0080379annotation not available (366 aa)
Lilra5Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5. (295 aa)
Cd79aCD79A antigen (immunoglobulin-associated alpha). (220 aa)
Akt2Thymoma viral proto-oncogene 2. (481 aa)
NfkbibNuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta. (359 aa)
Cd22CD22 antigen. (868 aa)
Inppl1Inositol polyphosphate phosphatase-like 1. (1257 aa)
PrkcbProtein kinase C, beta. (673 aa)
Cd19CD19 antigen. (547 aa)
Mapk3Mitogen-activated protein kinase 3. (380 aa)
Ifitm2Interferon induced transmembrane protein 2. (138 aa)
HrasHarvey rat sarcoma virus oncogene. (189 aa)
Cd81CD81 antigen. (236 aa)
IkbkbInhibitor of kappaB kinase beta. (757 aa)
Pik3r2Phosphoinositide-3-kinase regulatory subunit 2. (722 aa)
Nfatc3Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3. (1075 aa)
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
Server load: low (26%) [HD]