(90 nodes) Morphine addiction network (Mus spretus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MGP_SPRETEiJ_P0070336	annotation not available (95 aa)
	Adora1	Adenosine A1 receptor. (326 aa)
	Kcnj9	Potassium inwardly-rectifying channel, subfamily J, member 9. (393 aa)
	Oprm1	Opioid receptor, mu 1. (462 aa)
	Pde7b	Phosphodiesterase 7B. (498 aa)
	Gng7	Guanine nucleotide binding protein (G protein), gamma 7. (69 aa)
	Adcy1	Adenylate cyclase 1. (1118 aa)
	Gabrp	Gamma-aminobutyric acid (GABA) A receptor, pi. (440 aa)
	Gabrg2	Gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2. (474 aa)
	Gabra1	Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1. (455 aa)
	Gabra6	Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6. (453 aa)
	Gabrb2	Gamma-aminobutyric acid (GABA) A receptor, subunit beta 2. (512 aa)
	Arrb2	Arrestin, beta 2. (421 aa)
	Gngt2	Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2. (69 aa)
	Prkca	Protein kinase C, alpha. (672 aa)
	Adcy3	Adenylate cyclase 3. (1145 aa)
	Ptrhd1	peptidyl-tRNA hydrolase domain containing 1. (140 aa)
	Gng4	Guanine nucleotide binding protein (G protein), gamma 4. (75 aa)
	Drd1	Dopamine receptor D1. (446 aa)
	Grk6	G protein-coupled receptor kinase 6. (560 aa)
	Adcy2	Adenylate cyclase 2. (1095 aa)
	Pde8b	Phosphodiesterase 8B. (791 aa)
	Pde4d	Phosphodiesterase 4D, cAMP specific. (803 aa)
	Gng2	Guanine nucleotide binding protein (G protein), gamma 2. (71 aa)
	Adcy8	Adenylate cyclase 8. (1249 aa)
	Adcy6	Adenylate cyclase 6. (1168 aa)
	Pde1b	Phosphodiesterase 1B, Ca2+-calmodulin dependent. (535 aa)
	Adcy9	Adenylate cyclase 9. (1353 aa)
	Adcy5	Adenylate cyclase 5. (1265 aa)
	Gabrr3	Gamma-aminobutyric acid (GABA) receptor, rho 3. (464 aa)
	Kcnj6	Potassium inwardly-rectifying channel, subfamily J, member 6. (425 aa)
	Gng13	Guanine nucleotide binding protein (G protein), gamma 13. (67 aa)
	Gabbr1	Gamma-aminobutyric acid (GABA) B receptor, 1. (960 aa)
	Grk2	G protein-coupled receptor kinase 2. (689 aa)
	Gng3	Guanine nucleotide binding protein (G protein), gamma 3. (75 aa)
	Grk5	G protein-coupled receptor kinase 5. (590 aa)
	Cacna1b	Calcium channel, voltage-dependent, N type, alpha 1B subunit. (2330 aa)
	Kcnj3	Potassium inwardly-rectifying channel, subfamily J, member 3. (501 aa)
	Pde11a	Phosphodiesterase 11A. (933 aa)
	Pde1a	Phosphodiesterase 1A, calmodulin-dependent. (545 aa)
	Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus. (1133 aa)
	Pde7a	Phosphodiesterase 7A. (482 aa)
	Gnb4	Guanine nucleotide binding protein (G protein), beta 4. (340 aa)
	Gnai3	Guanine nucleotide binding protein (G protein), alpha inhibiting 3. (354 aa)
	MGP_SPRETEiJ_P0063388	annotation not available (68 aa)
	Prkacb	Protein kinase, cAMP dependent, catalytic, beta. (398 aa)
	Gabrr2	Gamma-aminobutyric acid (GABA) C receptor, subunit rho 2. (490 aa)
	Gabrr1	Gamma-aminobutyric acid (GABA) C receptor, subunit rho 1. (480 aa)
	Gabbr2	Gamma-aminobutyric acid (GABA) B receptor, 2. (940 aa)
	Gng10	Guanine nucleotide binding protein (G protein), gamma 10. (68 aa)
	Pde4b	Phosphodiesterase 4B, cAMP specific. (736 aa)
	Gabrd	Gamma-aminobutyric acid (GABA) A receptor, subunit delta. (449 aa)
	MGP_SPRETEiJ_P0068880	annotation not available (108 aa)
	Gnai1	Guanine nucleotide binding protein (G protein), alpha inhibiting 1. (354 aa)
	Gabrg1	Gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1. (465 aa)
	Gabra2	Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2. (451 aa)
	Gabra4	Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4. (578 aa)
	Gabrb1	Gamma-aminobutyric acid (GABA) A receptor, subunit beta 1. (474 aa)
	Grk3	G protein-coupled receptor kinase 3. (688 aa)
	Gnb2	Guanine nucleotide binding protein (G protein), beta 2. (382 aa)
	Gngt1	Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1. (74 aa)
	Gng11	Guanine nucleotide binding protein (G protein), gamma 11. (73 aa)
	Pde1c	Phosphodiesterase 1C. (766 aa)
	Gng12	Guanine nucleotide binding protein (G protein), gamma 12. (83 aa)
	Gnb3	Guanine nucleotide binding protein (G protein), beta 3. (340 aa)
	Pde3a	Phosphodiesterase 3A, cGMP inhibited. (1141 aa)
	Prkcg	Protein kinase C, gamma. (697 aa)
	Gng8	Guanine nucleotide binding protein (G protein), gamma 8. (70 aa)
	Gabrg3	Gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3. (467 aa)
	Gabra5	Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5. (463 aa)
	Gabrb3	Gamma-aminobutyric acid (GABA) A receptor, subunit beta 3. (507 aa)
	Pde8a	Phosphodiesterase 8A. (823 aa)
	Arrb1	Arrestin, beta 1. (419 aa)
	MGP_SPRETEiJ_P0084372	annotation not available (917 aa)
	Pde3b	Phosphodiesterase 3B, cGMP-inhibited. (1096 aa)
	Prkcb	Protein kinase C, beta. (673 aa)
	Pde4c	Phosphodiesterase 4C, cAMP specific. (686 aa)
	Prkaca	Protein kinase, cAMP dependent, catalytic, alpha. (351 aa)
	Cacna1a	Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit. (2385 aa)
	Gm5741	Predicted gene 5741. (72 aa)
	Adcy7	Adenylate cyclase 7. (1104 aa)
	MGP_SPRETEiJ_P0089054	annotation not available (354 aa)
	Pde4a	Phosphodiesterase 4A, cAMP specific. (844 aa)
	Kcnj5	Potassium inwardly-rectifying channel, subfamily J, member 5. (419 aa)
	Gnb5	Guanine nucleotide binding protein (G protein), beta 5. (395 aa)
	Gnai2	Guanine nucleotide binding protein (G protein), alpha inhibiting 2. (355 aa)
	Gabre	Gamma-aminobutyric acid (GABA) A receptor, subunit epsilon. (922 aa)
	Gabra3	Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3. (495 aa)
	Gabrq	Gamma-aminobutyric acid (GABA) A receptor, subunit theta. (525 aa)
	Arr3	Arrestin 3, retinal. (381 aa)

Your Current Organism:

Mus spretus

NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adcy1	Adcy2	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0036491	Adenylate cyclase 1.	Adenylate cyclase 2.	0.568
Adcy1	Adcy5	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0043297	Adenylate cyclase 1.	Adenylate cyclase 5.	0.562
Adcy1	Adcy6	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0041527	Adenylate cyclase 1.	Adenylate cyclase 6.	0.562
Adcy1	Adcy7	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0088964	Adenylate cyclase 1.	Adenylate cyclase 7.	0.589
Adcy1	Adcy9	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0042010	Adenylate cyclase 1.	Adenylate cyclase 9.	0.700
Adcy1	Gnai1	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0069365	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting 1.	0.911
Adcy1	Gnai2	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0093441	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting 2.	0.888
Adcy1	Gnai3	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0062299	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting 3.	0.776
Adcy1	Gnas	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0058692	Adenylate cyclase 1.	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus.	0.976
Adcy1	Gnb2	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0074327	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), beta 2.	0.835
Adcy1	Gnb3	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0079245	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), beta 3.	0.831
Adcy1	Gnb4	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0059504	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), beta 4.	0.739
Adcy1	Gnb5	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0092355	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), beta 5.	0.726
Adcy1	Gng10	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0064998	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), gamma 10.	0.809
Adcy1	Gng11	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0075286	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), gamma 11.	0.836
Adcy1	Gng12	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0077051	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), gamma 12.	0.672
Adcy1	Gng13	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0045204	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), gamma 13.	0.875
Adcy1	Gng2	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0037386	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), gamma 2.	0.669
Adcy1	Gng3	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0050016	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), gamma 3.	0.827
Adcy1	Gng4	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0035252	Adenylate cyclase 1.	Guanine nucleotide binding protein (G protein), gamma 4.	0.835