STRINGSTRING
Cxcr2 Cxcr2 Rufy4 Rufy4 Creb1 Creb1 Casp8 Casp8 Il1r1 Il1r1 Cxcr4 Cxcr4 Ptgs2 Ptgs2 Fasl Fasl Akt3 Akt3 MGP_SPRETEiJ_P0023054 MGP_SPRETEiJ_P0023054 Gng7 Gng7 Map2k2 Map2k2 Gna11 Gna11 Mdm2 Mdm2 Cdk4 Cdk4 Adcy1 Adcy1 Egfr Egfr Ppp3r1 Ppp3r1 Trp53 Trp53 Crk Crk Ccl2 Ccl2 Ccl12 Ccl12 Ccl5 Ccl5 Ccl3 Ccl3 Ccl4 Ccl4 Rps6kb1 Rps6kb1 Gngt2 Gngt2 Stat3 Stat3 Itgb3 Itgb3 Prkca Prkca Gna13 Gna13 Map2k6 Map2k6 Grb2 Grb2 Rac3 Rac3 Adcy3 Adcy3 Ptrhd1 Ptrhd1 Rock2 Rock2 Nfkbia Nfkbia Sos2 Sos2 Calm1 Calm1 Akt1 Akt1 Calml3 Calml3 MGP_SPRETEiJ_P0035125 MGP_SPRETEiJ_P0035125 MGP_SPRETEiJ_P0035127 MGP_SPRETEiJ_P0035127 Gng4 Gng4 E2f3 E2f3 Ripk1 Ripk1 Adcy2 Adcy2 Pik3r1 Pik3r1 Gng2 Gng2 Ppp3cb Ppp3cb Ptger2 Ptger2 Nfatc4 Nfatc4 Ptk2b Ptk2b Ppp3cc Ppp3cc Rb1 Rb1 Ptger4 Ptger4 Myc Myc Adcy8 Adcy8 Ptk2 Ptk2 Rac2 Rac2 Atf4 Atf4 Mapk12 Mapk12 Mapk11 Mapk11 Adcy6 Adcy6 Rhebl1 Rhebl1 Sp1 Sp1 Adcy9 Adcy9 Mapk1 Mapk1 Crkl Crkl Adcy5 Adcy5 Gsk3b Gsk3b Gm21970 Gm21970 Gng13 Gng13 Bak1 Bak1 Itpr3 Itpr3 Mapk14 Mapk14 Mapk13 Mapk13 Cdkn1a Cdkn1a Tapbp Tapbp Tap1 Tap1 Tap2 Tap2 Atf6b Atf6b Tnf Tnf MGP_SPRETEiJ_P0046403 MGP_SPRETEiJ_P0046403 H2-T24 H2-T24 MGP_SPRETEiJ_P0046563 MGP_SPRETEiJ_P0046563 H2-M11 H2-M11 MGP_SPRETEiJ_P0046581 MGP_SPRETEiJ_P0046581 MGP_SPRETEiJ_P0046582 MGP_SPRETEiJ_P0046582 2410137M14Rik 2410137M14Rik H2-M5 H2-M5 H2-M3 H2-M3 H2-M2 H2-M2 Vegfa Vegfa Sos1 Sos1 Calm2 Calm2 Rock1 Rock1 Tmem173 Tmem173 Nfatc1 Nfatc1 Rps6kb2 Rps6kb2 Rela Rela Plcb3 Plcb3 Gng3 Gng3 Gnaq Gnaq Fas Fas Chuk Chuk Traf2 Traf2 Bmyc Bmyc Tsc1 Tsc1 Atf2 Atf2 Cyct Cyct Itgav Itgav Creb3l1 Creb3l1 Plcb2 Plcb2 Pdia3 Pdia3 B2m B2m Il1b Il1b Plcb1 Plcb1 Plcb4 Plcb4 E2f1 E2f1 Src Src Nfatc2 Nfatc2 Gnas Gnas Pik3ca Pik3ca Gnb4 Gnb4 Arhgef11 Arhgef11 Il6ra Il6ra Creb3l4 Creb3l4 Csde1 Csde1 Nras Nras Rhoc Rhoc Gnai3 Gnai3 Nfkb1 Nfkb1 Ppp3ca Ppp3ca MGP_SPRETEiJ_P0063388 MGP_SPRETEiJ_P0063388 Prkacb Prkacb Ptger3 Ptger3 Creb3 Creb3 Ppp3r2 Ppp3r2 Gng10 Gng10 Ifnb1 Ifnb1 MGP_SPRETEiJ_P0065395 MGP_SPRETEiJ_P0065395 MGP_SPRETEiJ_P0065401 MGP_SPRETEiJ_P0065401 MGP_SPRETEiJ_P0065402 MGP_SPRETEiJ_P0065402 MGP_SPRETEiJ_P0065403 MGP_SPRETEiJ_P0065403 MGP_SPRETEiJ_P0065404 MGP_SPRETEiJ_P0065404 MGP_SPRETEiJ_P0065407 MGP_SPRETEiJ_P0065407 MGP_SPRETEiJ_P0065408 MGP_SPRETEiJ_P0065408 Cdkn2a Cdkn2a Jak1 Jak1 Calr4 Calr4 MGP_SPRETEiJ_P0066259 MGP_SPRETEiJ_P0066259 E2f2 E2f2 Casp9 Casp9 Mtor Mtor Pik3cd Pik3cd MGP_SPRETEiJ_P0068880 MGP_SPRETEiJ_P0068880 MGP_SPRETEiJ_P0069068 MGP_SPRETEiJ_P0069068 Gnai1 Gnai1 Rheb Rheb Il6 Il6 Pdgfra Pdgfra Pxn Pxn Gnb2 Gnb2 Gna12 Gna12 Rac1 Rac1 Gngt1 Gngt1 Gng11 Gng11 Creb3l2 Creb3l2 4921507P07Rik 4921507P07Rik Creb5 Creb5 4930544G11Rik 4930544G11Rik Gng12 Gng12 Itpr1 Itpr1 Raf1 Raf1 Cxcl12 Cxcl12 Bid Bid Gnb3 Gnb3 Tnfrsf1a Tnfrsf1a Kras Kras Itpr2 Itpr2 Prkcg Prkcg Gng8 Gng8 Calm3 Calm3 Arhgef1 Arhgef1 Akt2 Akt2 Irf3 Irf3 Bax Bax Akap13 Akap13 Prkcb Prkcb Mapk3 Mapk3 Hras Hras Fadd Fadd Ccnd1 Ccnd1 Ikbkb Ikbkb Eif4ebp1 Eif4ebp1 Pik3r2 Pik3r2 Ptger1 Ptger1 Prkaca Prkaca Calr Calr Gm5741 Gm5741 Adcy7 Adcy7 MGP_SPRETEiJ_P0089054 MGP_SPRETEiJ_P0089054 Cx3cl1 Cx3cl1 Tradd Tradd Nfatc3 Nfatc3 Bcar1 Bcar1 Arhgef12 Arhgef12 Il10ra Il10ra Calml4 Calml4 Map2k1 Map2k1 Gnb5 Gnb5 Cgas Cgas Pik3cb Pik3cb Gnai2 Gnai2 Ctnnb1 Ctnnb1 Ccr1 Ccr1 Ccr1l1 Ccr1l1 Ccr3 Ccr3 Ccr5 Ccr5 Eras Eras Elk1 Elk1 Ikbkg Ikbkg
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cxcr2Chemokine (C-X-C motif) receptor 2. (359 aa)
Rufy4RUN and FYVE domain containing 4. (564 aa)
Creb1cAMP responsive element binding protein 1. (341 aa)
Casp8Caspase 8. (500 aa)
Il1r1Interleukin 1 receptor, type I. (576 aa)
Cxcr4Chemokine (C-X-C motif) receptor 4. (359 aa)
Ptgs2Prostaglandin-endoperoxide synthase 2. (604 aa)
FaslFas ligand (TNF superfamily, member 6). (279 aa)
Akt3Thymoma viral proto-oncogene 3. (479 aa)
MGP_SPRETEiJ_P0023054annotation not available (249 aa)
Gng7Guanine nucleotide binding protein (G protein), gamma 7. (69 aa)
Map2k2Mitogen-activated protein kinase kinase 2. (401 aa)
Gna11Guanine nucleotide binding protein, alpha 11. (359 aa)
Mdm2Transformed mouse 3T3 cell double minute 2. (487 aa)
Cdk4Cyclin-dependent kinase 4. (303 aa)
Adcy1Adenylate cyclase 1. (1118 aa)
EgfrEpidermal growth factor receptor. (1210 aa)
Ppp3r1Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I). (170 aa)
Trp53Transformation related protein 53. (390 aa)
CrkV-crk avian sarcoma virus CT10 oncogene homolog. (304 aa)
Ccl2Chemokine (C-C motif) ligand 2. (148 aa)
Ccl12Chemokine (C-C motif) ligand 12. (105 aa)
Ccl5Chemokine (C-C motif) ligand 5. (91 aa)
Ccl3Chemokine (C-C motif) ligand 3. (92 aa)
Ccl4Chemokine (C-C motif) ligand 4. (92 aa)
Rps6kb1Ribosomal protein S6 kinase, polypeptide 1. (525 aa)
Gngt2Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2. (69 aa)
Stat3Signal transducer and activator of transcription 3. (770 aa)
Itgb3Integrin beta 3. (787 aa)
PrkcaProtein kinase C, alpha. (672 aa)
Gna13Guanine nucleotide binding protein, alpha 13. (377 aa)
Map2k6Mitogen-activated protein kinase kinase 6. (334 aa)
Grb2Growth factor receptor bound protein 2. (217 aa)
Rac3Rac family small GTPase 3. (192 aa)
Adcy3Adenylate cyclase 3. (1145 aa)
Ptrhd1peptidyl-tRNA hydrolase domain containing 1. (140 aa)
Rock2Rho-associated coiled-coil containing protein kinase 2. (1388 aa)
NfkbiaNuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha. (314 aa)
Sos2SOS Ras/Rho guanine nucleotide exchange factor 2. (1333 aa)
Calm1Calmodulin 1. (197 aa)
Akt1Thymoma viral proto-oncogene 1. (480 aa)
Calml3Calmodulin-like 3. (149 aa)
MGP_SPRETEiJ_P0035125annotation not available (148 aa)
MGP_SPRETEiJ_P0035127annotation not available (134 aa)
Gng4Guanine nucleotide binding protein (G protein), gamma 4. (75 aa)
E2f3E2F transcription factor 3. (457 aa)
Ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1. (655 aa)
Adcy2Adenylate cyclase 2. (1095 aa)
Pik3r1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
Gng2Guanine nucleotide binding protein (G protein), gamma 2. (71 aa)
Ppp3cbProtein phosphatase 3, catalytic subunit, beta isoform. (525 aa)
Ptger2Prostaglandin E receptor 2 (subtype EP2). (362 aa)
Nfatc4Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4. (901 aa)
Ptk2bPTK2 protein tyrosine kinase 2 beta. (1009 aa)
Ppp3ccProtein phosphatase 3, catalytic subunit, gamma isoform. (513 aa)
Rb1RB transcriptional corepressor 1. (921 aa)
Ptger4Prostaglandin E receptor 4 (subtype EP4). (513 aa)
MycMyelocytomatosis oncogene. (454 aa)
Adcy8Adenylate cyclase 8. (1249 aa)
Ptk2PTK2 protein tyrosine kinase 2. (1052 aa)
Rac2Rac family small GTPase 2. (192 aa)
Atf4Activating transcription factor 4. (349 aa)
Mapk12Mitogen-activated protein kinase 12. (367 aa)
Mapk11Mitogen-activated protein kinase 11. (364 aa)
Adcy6Adenylate cyclase 6. (1168 aa)
Rhebl1Ras homolog enriched in brain like 1. (184 aa)
Sp1Trans-acting transcription factor 1. (781 aa)
Adcy9Adenylate cyclase 9. (1353 aa)
Mapk1Mitogen-activated protein kinase 1. (358 aa)
CrklV-crk avian sarcoma virus CT10 oncogene homolog-like. (303 aa)
Adcy5Adenylate cyclase 5. (1265 aa)
Gsk3bGlycogen synthase kinase 3 beta. (433 aa)
Gm21970Predicted gene 21970. (294 aa)
Gng13Guanine nucleotide binding protein (G protein), gamma 13. (67 aa)
Bak1BCL2-antagonist/killer 1. (209 aa)
Itpr3Inositol 1,4,5-triphosphate receptor 3. (2670 aa)
Mapk14Mitogen-activated protein kinase 14. (360 aa)
Mapk13Mitogen-activated protein kinase 13. (366 aa)
Cdkn1aCyclin-dependent kinase inhibitor 1A (P21). (159 aa)
TapbpTAP binding protein. (466 aa)
Tap1Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (724 aa)
Tap2Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP). (703 aa)
Atf6bActivating transcription factor 6 beta. (709 aa)
TnfTumor necrosis factor. (235 aa)
MGP_SPRETEiJ_P0046403annotation not available (313 aa)
H2-T24Histocompatibility 2, T region locus 24. (363 aa)
MGP_SPRETEiJ_P0046563annotation not available (229 aa)
H2-M11Histocompatibility 2, M region locus 11. (334 aa)
MGP_SPRETEiJ_P0046581annotation not available (342 aa)
MGP_SPRETEiJ_P0046582annotation not available (345 aa)
2410137M14RikRIKEN cDNA 2410137M14 gene. (162 aa)
H2-M5Histocompatibility 2, M region locus 5. (348 aa)
H2-M3Histocompatibility 2, M region locus 3. (336 aa)
H2-M2Histocompatibility 2, M region locus 2. (343 aa)
VegfaVascular endothelial growth factor A. (392 aa)
Sos1SOS Ras/Rac guanine nucleotide exchange factor 1. (1319 aa)
Calm2Calmodulin 2. (149 aa)
Rock1Rho-associated coiled-coil containing protein kinase 1. (1354 aa)
Tmem173Transmembrane protein 173. (383 aa)
Nfatc1Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1. (939 aa)
Rps6kb2Ribosomal protein S6 kinase, polypeptide 2. (485 aa)
RelaV-rel reticuloendotheliosis viral oncogene homolog A (avian). (549 aa)
Plcb3Phospholipase C, beta 3. (1234 aa)
Gng3Guanine nucleotide binding protein (G protein), gamma 3. (75 aa)
GnaqGuanine nucleotide binding protein, alpha q polypeptide. (359 aa)
FasFas (TNF receptor superfamily member 6). (327 aa)
ChukConserved helix-loop-helix ubiquitous kinase. (745 aa)
Traf2TNF receptor-associated factor 2. (508 aa)
BmycBrain expressed myelocytomatosis oncogene. (170 aa)
Tsc1TSC complex subunit 1. (1161 aa)
Atf2Activating transcription factor 2. (487 aa)
CyctCytochrome c, testis. (105 aa)
ItgavIntegrin alpha V. (1044 aa)
Creb3l1cAMP responsive element binding protein 3-like 1. (520 aa)
Plcb2Phospholipase C, beta 2. (1181 aa)
Pdia3Protein disulfide isomerase associated 3. (505 aa)
B2mBeta-2 microglobulin. (119 aa)
Il1bInterleukin 1 beta. (269 aa)
Plcb1Phospholipase C, beta 1. (1216 aa)
Plcb4Phospholipase C, beta 4. (1239 aa)
E2f1E2F transcription factor 1. (385 aa)
SrcRous sarcoma oncogene. (541 aa)
Nfatc2Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2. (927 aa)
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus. (1133 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha. (1068 aa)
Gnb4Guanine nucleotide binding protein (G protein), beta 4. (340 aa)
Arhgef11Rho guanine nucleotide exchange factor (GEF) 11. (1552 aa)
Il6raInterleukin 6 receptor, alpha. (460 aa)
Creb3l4cAMP responsive element binding protein 3-like 4. (370 aa)
Csde1Cold shock domain containing E1, RNA binding. (798 aa)
NrasNeuroblastoma ras oncogene. (189 aa)
RhocRas homolog family member C. (193 aa)
Gnai3Guanine nucleotide binding protein (G protein), alpha inhibiting 3. (354 aa)
Nfkb1Nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105. (971 aa)
Ppp3caProtein phosphatase 3, catalytic subunit, alpha isoform. (521 aa)
MGP_SPRETEiJ_P0063388annotation not available (68 aa)
PrkacbProtein kinase, cAMP dependent, catalytic, beta. (398 aa)
Ptger3Prostaglandin E receptor 3 (subtype EP3). (366 aa)
Creb3cAMP responsive element binding protein 3. (379 aa)
Ppp3r2Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II). (179 aa)
Gng10Guanine nucleotide binding protein (G protein), gamma 10. (68 aa)
Ifnb1Interferon beta 1, fibroblast. (182 aa)
MGP_SPRETEiJ_P0065395annotation not available (189 aa)
MGP_SPRETEiJ_P0065401annotation not available (189 aa)
MGP_SPRETEiJ_P0065402annotation not available (128 aa)
MGP_SPRETEiJ_P0065403annotation not available (196 aa)
MGP_SPRETEiJ_P0065404annotation not available (190 aa)
MGP_SPRETEiJ_P0065407annotation not available (191 aa)
MGP_SPRETEiJ_P0065408annotation not available (191 aa)
Cdkn2aCyclin dependent kinase inhibitor 2A. (169 aa)
Jak1Janus kinase 1. (1153 aa)
Calr4Calreticulin 4. (439 aa)
MGP_SPRETEiJ_P0066259annotation not available (461 aa)
E2f2E2F transcription factor 2. (443 aa)
Casp9Caspase 9. (454 aa)
MtorMechanistic target of rapamycin kinase. (2549 aa)
Pik3cdPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta. (1047 aa)
MGP_SPRETEiJ_P0068880annotation not available (108 aa)
MGP_SPRETEiJ_P0069068annotation not available (93 aa)
Gnai1Guanine nucleotide binding protein (G protein), alpha inhibiting 1. (354 aa)
RhebRas homolog enriched in brain. (184 aa)
Il6Interleukin 6. (211 aa)
PdgfraPlatelet derived growth factor receptor, alpha polypeptide. (1089 aa)
PxnPaxillin. (591 aa)
Gnb2Guanine nucleotide binding protein (G protein), beta 2. (382 aa)
Gna12Guanine nucleotide binding protein, alpha 12. (379 aa)
Rac1Rac family small GTPase 1. (192 aa)
Gngt1Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1. (74 aa)
Gng11Guanine nucleotide binding protein (G protein), gamma 11. (73 aa)
Creb3l2cAMP responsive element binding protein 3-like 2. (521 aa)
4921507P07RikRIKEN cDNA 4921507P07 gene. (587 aa)
Creb5cAMP responsive element binding protein 5. (519 aa)
4930544G11RikRIKEN cDNA 4930544G11 gene. (193 aa)
Gng12Guanine nucleotide binding protein (G protein), gamma 12. (83 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor 1. (2749 aa)
Raf1V-raf-leukemia viral oncogene 1. (648 aa)
Cxcl12Chemokine (C-X-C motif) ligand 12. (119 aa)
BidBH3 interacting domain death agonist. (195 aa)
Gnb3Guanine nucleotide binding protein (G protein), beta 3. (340 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily, member 1a. (454 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (189 aa)
Itpr2Inositol 1,4,5-triphosphate receptor 2. (2701 aa)
PrkcgProtein kinase C, gamma. (697 aa)
Gng8Guanine nucleotide binding protein (G protein), gamma 8. (70 aa)
Calm3Calmodulin 3. (149 aa)
Arhgef1Rho guanine nucleotide exchange factor (GEF) 1. (967 aa)
Akt2Thymoma viral proto-oncogene 2. (481 aa)
Irf3Interferon regulatory factor 3. (419 aa)
BaxBCL2-associated X protein. (192 aa)
Akap13A kinase (PRKA) anchor protein 13. (2778 aa)
PrkcbProtein kinase C, beta. (673 aa)
Mapk3Mitogen-activated protein kinase 3. (380 aa)
HrasHarvey rat sarcoma virus oncogene. (189 aa)
FaddFas (TNFRSF6)-associated via death domain. (205 aa)
Ccnd1Cyclin D1. (295 aa)
IkbkbInhibitor of kappaB kinase beta. (757 aa)
Eif4ebp1Eukaryotic translation initiation factor 4E binding protein 1. (117 aa)
Pik3r2Phosphoinositide-3-kinase regulatory subunit 2. (722 aa)
Ptger1Prostaglandin E receptor 1 (subtype EP1). (405 aa)
PrkacaProtein kinase, cAMP dependent, catalytic, alpha. (351 aa)
CalrCalreticulin. (416 aa)
Gm5741Predicted gene 5741. (72 aa)
Adcy7Adenylate cyclase 7. (1104 aa)
MGP_SPRETEiJ_P0089054annotation not available (354 aa)
Cx3cl1Chemokine (C-X3-C motif) ligand 1. (395 aa)
TraddTNFRSF1A-associated via death domain. (310 aa)
Nfatc3Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3. (1075 aa)
Bcar1Breast cancer anti-estrogen resistance 1. (874 aa)
Arhgef12Rho guanine nucleotide exchange factor (GEF) 12. (1544 aa)
Il10raInterleukin 10 receptor, alpha. (575 aa)
Calml4Calmodulin-like 4. (153 aa)
Map2k1Mitogen-activated protein kinase kinase 1. (393 aa)
Gnb5Guanine nucleotide binding protein (G protein), beta 5. (395 aa)
CgasCyclic GMP-AMP synthase. (507 aa)
Pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta. (1064 aa)
Gnai2Guanine nucleotide binding protein (G protein), alpha inhibiting 2. (355 aa)
Ctnnb1Catenin (cadherin associated protein), beta 1. (785 aa)
Ccr1Chemokine (C-C motif) receptor 1. (355 aa)
Ccr1l1Chemokine (C-C motif) receptor 1-like 1. (356 aa)
Ccr3Chemokine (C-C motif) receptor 3. (359 aa)
Ccr5Chemokine (C-C motif) receptor 5. (354 aa)
ErasES cell-expressed Ras. (227 aa)
Elk1ELK1, member of ETS oncogene family. (429 aa)
IkbkgInhibitor of kappaB kinase gamma. (430 aa)
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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