(85 nodes) Chemical carcinogenesis network (Mus spretus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cyp2c39	Cytochrome P450, family 2, subfamily c, polypeptide 39. (490 aa)
	Cyp2c38	Cytochrome P450, family 2, subfamily c, polypeptide 38. (490 aa)
	Cyp2c29	Cytochrome P450, family 2, subfamily c, polypeptide 29. (490 aa)
	Cyp2c65	Cytochrome P450, family 2, subfamily c, polypeptide 65. (490 aa)
	Cyp2c55	Cytochrome P450, family 2, subfamily c, polypeptide 55. (490 aa)
	Gstp3	Glutathione S-transferase pi 3. (210 aa)
	Aldh3b1	Aldehyde dehydrogenase 3 family, member B1. (468 aa)
	MGP_SPRETEiJ_P0048149	annotation not available (85 aa)
	Cyp1b1	Cytochrome P450, family 1, subfamily b, polypeptide 1. (543 aa)
	Gm5678	Predicted gene 5678. (317 aa)
	Aldh3a1	Aldehyde dehydrogenase family 3, subfamily A1. (453 aa)
	Gstt2	Glutathione S-transferase, theta 2. (244 aa)
	Gstt4	Glutathione S-transferase, theta 4. (240 aa)
	Gstt1	Glutathione S-transferase, theta 1. (240 aa)
	Gstt3	Glutathione S-transferase, theta 3. (241 aa)
	Gm20441	Predicted gene 20441. (251 aa)
	Hsd11b1	Hydroxysteroid 11-beta dehydrogenase 1. (292 aa)
	Ephx1	Epoxide hydrolase 1, microsomal. (455 aa)
	Mgst3	Microsomal glutathione S-transferase 3. (153 aa)
	Ptgs2	Prostaglandin-endoperoxide synthase 2. (604 aa)
	Ugt1a1	UDP glucuronosyltransferase 1 family, polypeptide A1. (535 aa)
	Ugt1a2	UDP glucuronosyltransferase 1 family, polypeptide A2. (533 aa)
	Ugt1a5	UDP glucuronosyltransferase 1 family, polypeptide A5. (529 aa)
	MGP_SPRETEiJ_P0019979	annotation not available (530 aa)
	MGP_SPRETEiJ_P0019977	annotation not available (530 aa)
	MGP_SPRETEiJ_P0019976	annotation not available (530 aa)
	Ugt1a8	UDP glucuronosyltransferase 1 family, polypeptide A8. (530 aa)
	Ugt1a9	UDP glucuronosyltransferase 1 family, polypeptide A9. (528 aa)
	Gsta3	Glutathione S-transferase, alpha 3. (221 aa)
	MGP_SPRETEiJ_P0092448	annotation not available (111 aa)
	MGP_SPRETEiJ_P0092447	annotation not available (111 aa)
	Gsta4	Glutathione S-transferase, alpha 4. (222 aa)
	Cyp1a1	Cytochrome P450, family 1, subfamily a, polypeptide 1. (524 aa)
	Cyp1a2	Cytochrome P450, family 1, subfamily a, polypeptide 2. (513 aa)
	Nat3	N-acetyltransferase 3. (290 aa)
	Nat2	N-acetyltransferase 2 (arylamine N-acetyltransferase). (290 aa)
	Nat1	N-acetyl transferase 1. (290 aa)
	Cyp2e1	Cytochrome P450, family 2, subfamily e, polypeptide 1. (493 aa)
	MGP_SPRETEiJ_P0085593	annotation not available (183 aa)
	Chrna7	Cholinergic receptor, nicotinic, alpha polypeptide 7. (502 aa)
	Cyp2b19	Cytochrome P450, family 2, subfamily b, polypeptide 19. (492 aa)
	Cyp2b23	Cytochrome P450, family 2, subfamily b, polypeptide 23. (491 aa)
	Cyp2b9	Cytochrome P450, family 2, subfamily b, polypeptide 9. (491 aa)
	Cyp2b10	Cytochrome P450, family 2, subfamily b, polypeptide 10. (500 aa)
	Sult2a8	Sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8. (282 aa)
	Sult2a6	Sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6. (285 aa)
	MGP_SPRETEiJ_P0080787	annotation not available (144 aa)
	Mgst1	Microsomal glutathione S-transferase 1. (229 aa)
	Hpgds	Hematopoietic prostaglandin D synthase. (199 aa)
	Gstk1	Glutathione S-transferase kappa 1. (226 aa)
	MGP_SPRETEiJ_P0074990	annotation not available (503 aa)
	MGP_SPRETEiJ_P0074989	annotation not available (503 aa)
	MGP_SPRETEiJ_P0074988	annotation not available (503 aa)
	Cyp3a13	Cytochrome P450, family 3, subfamily a, polypeptide 13. (503 aa)
	MGP_SPRETEiJ_P0071552	annotation not available (694 aa)
	Ugt2a2	UDP glucuronosyltransferase 2 family, polypeptide A2. (528 aa)
	MGP_SPRETEiJ_P0071550	annotation not available (528 aa)
	Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3. (534 aa)
	MGP_SPRETEiJ_P0071546	annotation not available (530 aa)
	MGP_SPRETEiJ_P0071545	annotation not available (530 aa)
	MGP_SPRETEiJ_P0071544	annotation not available (362 aa)
	Ugt2b35	UDP glucuronosyltransferase 2 family, polypeptide B35. (534 aa)
	Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1. (529 aa)
	Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34. (532 aa)
	Kyat3	Kynurenine aminotransferase 3. (455 aa)
	Adh5	Alcohol dehydrogenase 5 (class III), chi polypeptide. (374 aa)
	Adh4	Alcohol dehydrogenase 4 (class II), pi polypeptide. (377 aa)
	Adh1	Alcohol dehydrogenase 1 (class I). (375 aa)
	Adh7	Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide. (374 aa)
	Gstm4	Glutathione S-transferase, mu 4. (218 aa)
	Gstm1	Glutathione S-transferase, mu 1. (244 aa)
	MGP_SPRETEiJ_P0062274	annotation not available (218 aa)
	Gstm3	Glutathione S-transferase, mu 3. (218 aa)
	Gstm6	Glutathione S-transferase, mu 6. (232 aa)
	Gstm7	Glutathione S-transferase, mu 7. (218 aa)
	Gstm5	Glutathione S-transferase, mu 5. (223 aa)
	Arnt	Aryl hydrocarbon receptor nuclear translocator. (789 aa)
	MGP_SPRETEiJ_P0059871	annotation not available (82 aa)
	Kyat1	Kynurenine aminotransferase 1. (424 aa)
	Gsto2	Glutathione S-transferase omega 2. (248 aa)
	Gsto1	Glutathione S-transferase omega 1. (240 aa)
	Cyp2c23	Cytochrome P450, family 2, subfamily c, polypeptide 23. (494 aa)
	Cyp2c70	Cytochrome P450, family 2, subfamily c, polypeptide 70. (489 aa)
	Cyp2c50	Cytochrome P450, family 2, subfamily c, polypeptide 50. (494 aa)
	MGP_SPRETEiJ_P0050719	annotation not available (178 aa)

Your Current Organism:

Mus spretus

NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adh1	Adh4	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0063177	Alcohol dehydrogenase 1 (class I).	Alcohol dehydrogenase 4 (class II), pi polypeptide.	0.801
Adh1	Adh5	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0063178	Alcohol dehydrogenase 1 (class I).	Alcohol dehydrogenase 5 (class III), chi polypeptide.	0.606
Adh1	Adh7	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0063165	Alcohol dehydrogenase 1 (class I).	Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide.	0.801
Adh1	Aldh3a1	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0028465	Alcohol dehydrogenase 1 (class I).	Aldehyde dehydrogenase family 3, subfamily A1.	0.930
Adh1	Aldh3b1	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0049350	Alcohol dehydrogenase 1 (class I).	Aldehyde dehydrogenase 3 family, member B1.	0.880
Adh1	Cyp2e1	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0086477	Alcohol dehydrogenase 1 (class I).	Cytochrome P450, family 2, subfamily e, polypeptide 1.	0.951
Adh1	Gm20441	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0024597	Alcohol dehydrogenase 1 (class I).	Predicted gene 20441.	0.668
Adh1	Gm5678	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0044287	Alcohol dehydrogenase 1 (class I).	Predicted gene 5678.	0.403
Adh1	Gsta3	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0017877	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase, alpha 3.	0.664
Adh1	Gsta4	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0092441	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase, alpha 4.	0.731
Adh1	Gstk1	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0076336	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase kappa 1.	0.657
Adh1	Gstm1	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0062280	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase, mu 1.	0.607
Adh1	Gstm3	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0062273	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase, mu 3.	0.479
Adh1	Gstm4	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0062282	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase, mu 4.	0.673
Adh1	Gstm5	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0062259	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase, mu 5.	0.720
Adh1	Gstm6	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0062267	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase, mu 6.	0.479
Adh1	Gstm7	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0062262	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase, mu 7.	0.689
Adh1	Gsto1	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0051114	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase omega 1.	0.725
Adh1	Gsto2	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0051118	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase omega 2.	0.725
Adh1	Gstp3	MGP_SPRETEiJ_P0063169	MGP_SPRETEiJ_P0049375	Alcohol dehydrogenase 1 (class I).	Glutathione S-transferase pi 3.	0.743