Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Chmp4b | Chmp6 | ENSRNOP00000067294 | ENSRNOP00000005379 | Uncharacterized protein. | Chromatin modifying protein 6 (Predicted). | 0.969 |
| Chmp4b | Mvb12a | ENSRNOP00000067294 | ENSRNOP00000024413 | Uncharacterized protein. | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | 0.856 |
| Chmp4b | Mvb12b | ENSRNOP00000067294 | ENSRNOP00000023172 | Uncharacterized protein. | Multivesicular body subunit 12B. | 0.860 |
| Chmp4b | Snf8 | ENSRNOP00000067294 | ENSRNOP00000008964 | Uncharacterized protein. | Vacuolar-sorting protein SNF8; Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization (By similarity). Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in tr [...] | 0.935 |
| Chmp4b | Tsg101 | ENSRNOP00000067294 | ENSRNOP00000018194 | Uncharacterized protein. | Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). It may also play a role in the [...] | 0.870 |
| Chmp4b | Ubap1 | ENSRNOP00000067294 | ENSRNOP00000062034 | Uncharacterized protein. | Ubiquitin-associated protein 1; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2. | 0.809 |
| Chmp4b | Vps25 | ENSRNOP00000067294 | ENSRNOP00000044397 | Uncharacterized protein. | Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. | 0.925 |
| Chmp4b | Vps28 | ENSRNOP00000067294 | ENSRNOP00000019707 | Uncharacterized protein. | Vacuolar protein sorting-associated protein 28 homolog; Component of the endosomal sorting complex required for transport-I (ESCRT-I) complex, a regulator of vesicular trafficking process. The ESCRT-I complex participates in the sorting of membrane proteins into vesicles that bud into late endosomal compartments called multivesicular bodies, and is also involved in the budding of many viruses. | 0.852 |
| Chmp4b | Vps36 | ENSRNOP00000067294 | ENSRNOP00000016995 | Uncharacterized protein. | Vacuolar protein-sorting-associated protein 36; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may a [...] | 0.894 |
| Chmp4b | Vps37a | ENSRNOP00000067294 | ENSRNOP00000016321 | Uncharacterized protein. | Similar to DNA segment, Chr 8, ERATO Doi 531, expressed, isoform CRA_c. | 0.840 |
| Chmp4b | Vps37b | ENSRNOP00000067294 | ENSRNOP00000001445 | Uncharacterized protein. | Vacuolar protein sorting 37B (Yeast) (Predicted), isoform CRA_b. | 0.844 |
| Chmp6 | Chmp4b | ENSRNOP00000005379 | ENSRNOP00000067294 | Chromatin modifying protein 6 (Predicted). | Uncharacterized protein. | 0.969 |
| Chmp6 | Mvb12a | ENSRNOP00000005379 | ENSRNOP00000024413 | Chromatin modifying protein 6 (Predicted). | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | 0.881 |
| Chmp6 | Mvb12b | ENSRNOP00000005379 | ENSRNOP00000023172 | Chromatin modifying protein 6 (Predicted). | Multivesicular body subunit 12B. | 0.896 |
| Chmp6 | Snf8 | ENSRNOP00000005379 | ENSRNOP00000008964 | Chromatin modifying protein 6 (Predicted). | Vacuolar-sorting protein SNF8; Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization (By similarity). Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in tr [...] | 0.986 |
| Chmp6 | Tsg101 | ENSRNOP00000005379 | ENSRNOP00000018194 | Chromatin modifying protein 6 (Predicted). | Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). It may also play a role in the [...] | 0.960 |
| Chmp6 | Ubap1 | ENSRNOP00000005379 | ENSRNOP00000062034 | Chromatin modifying protein 6 (Predicted). | Ubiquitin-associated protein 1; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2. | 0.892 |
| Chmp6 | Vps25 | ENSRNOP00000005379 | ENSRNOP00000044397 | Chromatin modifying protein 6 (Predicted). | Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. | 0.999 |
| Chmp6 | Vps28 | ENSRNOP00000005379 | ENSRNOP00000019707 | Chromatin modifying protein 6 (Predicted). | Vacuolar protein sorting-associated protein 28 homolog; Component of the endosomal sorting complex required for transport-I (ESCRT-I) complex, a regulator of vesicular trafficking process. The ESCRT-I complex participates in the sorting of membrane proteins into vesicles that bud into late endosomal compartments called multivesicular bodies, and is also involved in the budding of many viruses. | 0.981 |
| Chmp6 | Vps36 | ENSRNOP00000005379 | ENSRNOP00000016995 | Chromatin modifying protein 6 (Predicted). | Vacuolar protein-sorting-associated protein 36; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may a [...] | 0.980 |
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