STRINGSTRING
D3ZU53_RAT D3ZU53_RAT Fmo3 Fmo3 Sec14l3 Sec14l3 Cdkl1 Cdkl1 Olr1607 Olr1607 Olr434 Olr434 Olr1621 Olr1621 Olr1622 Olr1622 Olfr286 Olfr286 Dennd4a Dennd4a Tmem213 Tmem213 Olr68 Olr68 Olr70 Olr70 Taar1 Taar1 Taar7b Taar7b Olr142 Olr142 Olr143 Olr143 Olr148 Olr148 Olr153 Olr153 Olr178 Olr178 Olr1666 Olr1666 Olr853 Olr853 Plekhb1 Plekhb1 Pcdhb1 Pcdhb1 Olr336 Olr336 Rtp1 Rtp1 Taar2 Taar2 Olr1637 Olr1637 Taar3 Taar3 Olr202 Olr202 Rtp2 Rtp2 Taar9 Taar9 Olr139 Olr139 Taar8a Taar8a Olr820 Olr820 Olr418 Olr418 Olr67 Olr67 Taar7c Taar7c Olr119 Olr119 Olr179 Olr179 Olr821 Olr821 Olr1710 Olr1710 LOC100910174 LOC100910174 Olr132 Olr132 Olr1309 Olr1309 Taar7g Taar7g Taar7e Taar7e Olr1528 Olr1528 Clstn1 Clstn1 Trpc2 Trpc2 Olr1396 Olr1396 Olr436 Olr436 Taar7d Taar7d Taar4 Taar4 Olr137 Olr137 Olr783 Olr783 Olr439 Olr439 Vom1r21 Vom1r21 Odr4 Odr4 Mslnl Mslnl Pcdhgb7 Pcdhgb7 Taar5 Taar5 Camta1 Camta1 Or7e24 Or7e24 Olr1750 Olr1750 Vom1r39 Vom1r39 Olr472 Olr472 M0R7C8_RAT M0R7C8_RAT Olr140 Olr140 Ceacam9 Ceacam9 Olfr574 Olfr574 Olr1530 Olr1530 LOC103690077 LOC103690077 Smap1 Smap1 Vom2r25 Vom2r25 Olr358 Olr358 Olr154 Olr154 Ric8b Ric8b Olr172 Olr172 Ano2 Ano2 LOC103693685 LOC103693685 Taar6 Taar6 Vom1r97 Vom1r97 Olr352 Olr352 Olr363 Olr363 LOC103693822 LOC103693822 Olr176 Olr176 A0A0G2K3R0_RAT A0A0G2K3R0_RAT Olr1633-2 Olr1633-2 LOC686683 LOC686683 Olr954 Olr954 Heca Heca Taar8b Taar8b
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D3ZU53_RATUncharacterized protein. (325 aa)
Fmo3Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] (531 aa)
Sec14l3Similar to SEC14 (S. cerevisiae)-like 2 (Predicted), isoform CRA_b. (412 aa)
Cdkl1Cyclin-dependent kinase-like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. (352 aa)
Olr1607Olfactory receptor. (315 aa)
Olr434Olfactory receptor. (327 aa)
Olr1621Olfactory receptor. (328 aa)
Olr1622Olfactory receptor. (312 aa)
Olfr286Olfactory receptor. (322 aa)
Dennd4aDENN domain-containing 4A. (1873 aa)
Tmem213Transmembrane protein 213. (127 aa)
Olr68Olfactory receptor. (322 aa)
Olr70Olfactory receptor. (313 aa)
Taar1Trace amine-associated receptor 1; Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained spe [...] (332 aa)
Taar7bTrace amine-associated receptor 7b; Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood; Belongs to the G-protein coupled receptor 1 family. (358 aa)
Olr142Olfactory receptor. (314 aa)
Olr143Olfactory receptor. (312 aa)
Olr148Olfactory receptor. (323 aa)
Olr153Olfactory receptor. (324 aa)
Olr178Olfactory receptor. (312 aa)
Olr1666Olfactory receptor. (312 aa)
Olr853Olfactory receptor. (312 aa)
Plekhb1Pleckstrin homology domain-containing family B member 1. (223 aa)
Pcdhb1Protocadherin beta 1. (818 aa)
Olr336Olfactory receptor. (320 aa)
Rtp1Receptor (chemosensory) transporter protein 1. (263 aa)
Taar2Trace amine-associated receptor 2; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. (339 aa)
Olr1637Olfactory receptor. (331 aa)
Taar3Trace amine-associated receptor 3; Olfactory receptor activated by several primary trace amines, including isoamylamine. Activated by isoamylamine and cyclohexylamine, but not to the corresponding alcohols, isoamylalcohol and cyclohexanol. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase (By similarity). (342 aa)
Olr202Olfactory receptor. (322 aa)
Rtp2Receptor transporter protein 2 (Predicted), isoform CRA_b. (223 aa)
Taar9Trace amine-associated receptor 9; Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood; Belongs to the G-protein coupled receptor 1 family. (338 aa)
Olr139Olfactory receptor. (315 aa)
Taar8aTrace amine-associated receptor 8a; Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood; Belongs to the G-protein coupled receptor 1 family. (374 aa)
Olr820Olfactory receptor. (320 aa)
Olr418Olfactory receptor. (310 aa)
Olr67Olfactory receptor. (312 aa)
Taar7cTrace amine-associated receptor 7c; Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood (By similarity). Belongs to the G-protein coupled receptor 1 family. (358 aa)
Olr119Olfactory receptor. (317 aa)
Olr179Olfactory receptor. (312 aa)
Olr821Olfactory receptor. (320 aa)
Olr1710Olfactory receptor 1710. (312 aa)
LOC100910174Trace amine-associated receptor 8a. (374 aa)
Olr132Olfactory receptor. (315 aa)
Olr1309Olfactory receptor 1309. (314 aa)
Taar7gTrace amine-associated receptor 7g; Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood; Belongs to the G-protein coupled receptor 1 family. (358 aa)
Taar7eTrace amine-associated receptor 7e; Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood; Belongs to the G-protein coupled receptor 1 family. (358 aa)
Olr1528Olfactory receptor. (306 aa)
Clstn1Soluble Alc-alpha; Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. As intracellular fragment AlcICD, suppresses APBB1-dependent tran [...] (952 aa)
Trpc2Short transient receptor potential channel 2; Thought to form a receptor-activated calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Is not activated by intracellular calcium store depletion. (1170 aa)
Olr1396Olfactory receptor. (311 aa)
Olr436Olfactory receptor. (309 aa)
Taar7dTrace amine-associated receptor 7d; Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood; Belongs to the G-protein coupled receptor 1 family. (358 aa)
Taar4Trace amine-associated receptor 4; Olfactory receptor specific for 2-phenylethylamine, a trace amine present at high concentration in the urine of carnivore species, playing a key role in fear and avoidance responses. 2-phenylethylamine acts as a kairomone in the chemical detection of carnivore odor and triggers fear in mice. This receptor is probably mediated by the G(s)- class of G-proteins which activate adenylate cyclase (By similarity). (347 aa)
Olr137Olfactory receptor. (321 aa)
Olr783Olfactory receptor. (312 aa)
Olr439Olfactory receptor. (309 aa)
Vom1r21Vomeronasal type-1 receptor. (289 aa)
Odr4Odr-4 GPCR localization factor homolog. (447 aa)
MslnlMesothelin-like. (686 aa)
Pcdhgb7Protocadherin gamma subfamily B, 7. (807 aa)
Taar5Trace amine-associated receptor 5; Olfactory receptor specific for trimethylamine, a trace amine. Also activated at lower level by dimethylethylamine. Trimethylamine is a bacterial metabolite found in some animal odors, and is a repulsive odor associated with bad breath and spoiled food. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase (By similarity). (337 aa)
Camta1Calmodulin-binding transcription activator 1. (1609 aa)
Or7e24Putative gustatory receptor clone PTE01; Possible taste receptor. (331 aa)
Olr1750Olfactory receptor. (310 aa)
Vom1r39Vomeronasal type-1 receptor. (305 aa)
Olr472Olfactory receptor. (327 aa)
M0R7C8_RATOlfactory receptor. (299 aa)
Olr140Olfactory receptor. (315 aa)
Ceacam9Carcinoembryonic antigen-related cell adhesion molecule 9. (229 aa)
Olfr574Olfactory receptor. (346 aa)
Olr1530Olfactory receptor. (305 aa)
LOC103690077Cyclic nucleotide-gated olfactory channel-like. (538 aa)
Smap1Small ArfGAP 1. (440 aa)
Vom2r25Vomeronasal 2 receptor, 25. (860 aa)
Olr358Olfactory receptor. (310 aa)
Olr154Olfactory receptor. (317 aa)
Ric8bSynembryn-B; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction (Probable). (536 aa)
Olr172Olfactory receptor. (318 aa)
Ano2Anoctamin. (998 aa)
LOC103693685Olfactory receptor 6P1. (317 aa)
Taar6Trace amine-associated receptor 6; Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood; Belongs to the G-protein coupled receptor 1 family. (345 aa)
Vom1r97Vomeronasal type-1 receptor 97; Putative pheromone receptor implicated in the regulation of social as well as reproductive behavior. (310 aa)
Olr352Olfactory receptor. (307 aa)
Olr363Olfactory receptor. (312 aa)
LOC103693822Olfactory receptor 11H4-like. (324 aa)
Olr176Olfactory receptor. (318 aa)
A0A0G2K3R0_RATUncharacterized protein. (83 aa)
Olr1633-2Olfactory receptor 1633. (328 aa)
LOC686683Olfactory receptor. (313 aa)
Olr954Olfactory receptor 6C2-like. (317 aa)
HecaHeadcase homolog (Drosophila) (Predicted). (415 aa)
Taar8bTrace amine-associated receptor 8c; Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood; Belongs to the G-protein coupled receptor 1 family. (344 aa)
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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