Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Aspscr1 | Faf1 | ENSRNOP00000051827 | ENSRNOP00000011765 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | FAS-associated factor 1; Ubiquitin-binding protein. Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation. Potentiates but cannot initiate FAS-induced apoptosis. | 0.950 |
| Aspscr1 | Faf2 | ENSRNOP00000051827 | ENSRNOP00000068627 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | FAS-associated factor 2; Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. By controlling the steady- state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway. Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis. | 0.541 |
| Aspscr1 | LOC100911374 | ENSRNOP00000051827 | ENSRNOP00000072788 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | UBX domain-containing protein 7-like. | 0.944 |
| Aspscr1 | Nploc4 | ENSRNOP00000051827 | ENSRNOP00000051856 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | Nuclear protein localization protein 4 homolog; The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation [...] | 0.960 |
| Aspscr1 | Nsfl1c | ENSRNOP00000051827 | ENSRNOP00000011654 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro) (By similarity). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase (By similarity). Also, regulates spindle orientation during mitosis (By similarity). | 0.959 |
| Aspscr1 | Spata5 | ENSRNOP00000051827 | ENSRNOP00000071455 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | Spermatogenesis-associated 5. | 0.786 |
| Aspscr1 | Spata5l1 | ENSRNOP00000051827 | ENSRNOP00000040861 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | Spermatogenesis-associated 5-like 1. | 0.786 |
| Aspscr1 | Ubxn1 | ENSRNOP00000051827 | ENSRNOP00000026651 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | UBX domain-containing protein 1; Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'- linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1- BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol (By similarity). | 0.524 |
| Aspscr1 | Ubxn10 | ENSRNOP00000051827 | ENSRNOP00000000167 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | UBX domain containing 3, isoform CRA_a. | 0.948 |
| Aspscr1 | Ubxn11 | ENSRNOP00000051827 | ENSRNOP00000021342 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | UBX domain-containing protein 11; May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13. | 0.627 |
| Aspscr1 | Ubxn2a | ENSRNOP00000051827 | ENSRNOP00000006668 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | RCG62119, isoform CRA_a. | 0.955 |
| Aspscr1 | Ubxn2b | ENSRNOP00000051827 | ENSRNOP00000012551 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | UBX domain-containing protein 2B; Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, r [...] | 0.959 |
| Aspscr1 | Ubxn4 | ENSRNOP00000051827 | ENSRNOP00000004878 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | UBX domain-containing protein 4; Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD. | 0.788 |
| Aspscr1 | Ubxn6 | ENSRNOP00000051827 | ENSRNOP00000071261 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | UBX domain protein 6. | 0.957 |
| Aspscr1 | Ubxn7 | ENSRNOP00000051827 | ENSRNOP00000066087 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | UBX domain-containing protein 7. | 0.944 |
| Aspscr1 | Ubxn8 | ENSRNOP00000051827 | ENSRNOP00000020347 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | UBX domain containing 6 (Predicted), isoform CRA_a. | 0.531 |
| Aspscr1 | Ufd1 | ENSRNOP00000051827 | ENSRNOP00000067081 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | Ubiquitin recognition factor in ER-associated degradation protein 1; Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1- VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-deriv [...] | 0.523 |
| Aspscr1 | Vcp | ENSRNOP00000051827 | ENSRNOP00000040121 | ASPSCR1 tether for SLC2A4, UBX domain-containing. | Transitional endoplasmic reticulum ATPase; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is neces [...] | 0.952 |
| Faf1 | Aspscr1 | ENSRNOP00000011765 | ENSRNOP00000051827 | FAS-associated factor 1; Ubiquitin-binding protein. Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation. Potentiates but cannot initiate FAS-induced apoptosis. | ASPSCR1 tether for SLC2A4, UBX domain-containing. | 0.950 |
| Faf1 | Faf2 | ENSRNOP00000011765 | ENSRNOP00000068627 | FAS-associated factor 1; Ubiquitin-binding protein. Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation. Potentiates but cannot initiate FAS-induced apoptosis. | FAS-associated factor 2; Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. By controlling the steady- state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway. Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis. | 0.780 |
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