node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hltf | LOC100125386 | ENSRNOP00000069487 | ENSRNOP00000070673 | Helicase-like transcription factor. | LOC100125386 protein. | 0.792 |
Hltf | Mad2l2 | ENSRNOP00000069487 | ENSRNOP00000052521 | Helicase-like transcription factor. | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | 0.523 |
Hltf | Pcna | ENSRNOP00000069487 | ENSRNOP00000028887 | Helicase-like transcription factor. | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.939 |
Hltf | Polh | ENSRNOP00000069487 | ENSRNOP00000026049 | Helicase-like transcription factor. | Polymerase (DNA directed), eta (RAD 30 related) (Predicted). | 0.648 |
Hltf | Rad18 | ENSRNOP00000069487 | ENSRNOP00000063400 | Helicase-like transcription factor. | RAD18 E3 ubiquitin protein ligase. | 0.987 |
Hltf | Rev1 | ENSRNOP00000069487 | ENSRNOP00000059807 | Helicase-like transcription factor. | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | 0.739 |
Hltf | Rev3l | ENSRNOP00000069487 | ENSRNOP00000054053 | Helicase-like transcription factor. | REV3-like, DNA directed polymerase zeta catalytic subunit. | 0.789 |
LOC100125386 | Hltf | ENSRNOP00000070673 | ENSRNOP00000069487 | LOC100125386 protein. | Helicase-like transcription factor. | 0.792 |
LOC100125386 | Mad2l2 | ENSRNOP00000070673 | ENSRNOP00000052521 | LOC100125386 protein. | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | 0.444 |
LOC100125386 | Pcna | ENSRNOP00000070673 | ENSRNOP00000028887 | LOC100125386 protein. | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.535 |
LOC100125386 | Polh | ENSRNOP00000070673 | ENSRNOP00000026049 | LOC100125386 protein. | Polymerase (DNA directed), eta (RAD 30 related) (Predicted). | 0.685 |
LOC100125386 | Poli | ENSRNOP00000070673 | ENSRNOP00000016189 | LOC100125386 protein. | Polymerase (DNA directed), iota (Predicted), isoform CRA_c. | 0.422 |
LOC100125386 | Rad18 | ENSRNOP00000070673 | ENSRNOP00000063400 | LOC100125386 protein. | RAD18 E3 ubiquitin protein ligase. | 0.452 |
LOC100125386 | Rev1 | ENSRNOP00000070673 | ENSRNOP00000059807 | LOC100125386 protein. | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | 0.540 |
LOC100125386 | Rev3l | ENSRNOP00000070673 | ENSRNOP00000054053 | LOC100125386 protein. | REV3-like, DNA directed polymerase zeta catalytic subunit. | 0.719 |
Mad2l2 | Hltf | ENSRNOP00000052521 | ENSRNOP00000069487 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | Helicase-like transcription factor. | 0.523 |
Mad2l2 | LOC100125386 | ENSRNOP00000052521 | ENSRNOP00000070673 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | LOC100125386 protein. | 0.444 |
Mad2l2 | Pcna | ENSRNOP00000052521 | ENSRNOP00000028887 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.766 |
Mad2l2 | Polh | ENSRNOP00000052521 | ENSRNOP00000026049 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | Polymerase (DNA directed), eta (RAD 30 related) (Predicted). | 0.857 |
Mad2l2 | Poli | ENSRNOP00000052521 | ENSRNOP00000016189 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | Polymerase (DNA directed), iota (Predicted), isoform CRA_c. | 0.910 |