Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Aldh18a1 | Aldh18a1-2 | ENSRNOP00000020940 | ENSRNOP00000074318 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Aldehyde dehydrogenase 18 family, member A1. | 0.999 |
| Aldh18a1 | Iffo2 | ENSRNOP00000020940 | ENSRNOP00000069221 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma- semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). | 0.877 |
| Aldh18a1 | Prodh1 | ENSRNOP00000020940 | ENSRNOP00000002576 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.692 |
| Aldh18a1 | Pycr1 | ENSRNOP00000020940 | ENSRNOP00000051832 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. | 0.921 |
| Aldh18a1 | Pycr2 | ENSRNOP00000020940 | ENSRNOP00000004379 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Pyrroline-5-carboxylate reductase 2; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (By similarity). Involved in cellular response to oxidative stress (By similarity); Belongs to the pyrroline-5-carboxylate reductase family. | 0.943 |
| Aldh18a1 | Pycr3 | ENSRNOP00000020940 | ENSRNOP00000071183 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Pyrroline-5-carboxylate reductase 3; Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. | 0.950 |
| Aldh18a1-2 | Aldh18a1 | ENSRNOP00000074318 | ENSRNOP00000020940 | Aldehyde dehydrogenase 18 family, member A1. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.999 |
| Aldh18a1-2 | Iffo2 | ENSRNOP00000074318 | ENSRNOP00000069221 | Aldehyde dehydrogenase 18 family, member A1. | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma- semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). | 0.880 |
| Aldh18a1-2 | Prodh1 | ENSRNOP00000074318 | ENSRNOP00000002576 | Aldehyde dehydrogenase 18 family, member A1. | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.626 |
| Aldh18a1-2 | Pycr1 | ENSRNOP00000074318 | ENSRNOP00000051832 | Aldehyde dehydrogenase 18 family, member A1. | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. | 0.918 |
| Aldh18a1-2 | Pycr2 | ENSRNOP00000074318 | ENSRNOP00000004379 | Aldehyde dehydrogenase 18 family, member A1. | Pyrroline-5-carboxylate reductase 2; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (By similarity). Involved in cellular response to oxidative stress (By similarity); Belongs to the pyrroline-5-carboxylate reductase family. | 0.921 |
| Aldh18a1-2 | Pycr3 | ENSRNOP00000074318 | ENSRNOP00000071183 | Aldehyde dehydrogenase 18 family, member A1. | Pyrroline-5-carboxylate reductase 3; Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. | 0.933 |
| Iffo2 | Aldh18a1 | ENSRNOP00000069221 | ENSRNOP00000020940 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma- semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.877 |
| Iffo2 | Aldh18a1-2 | ENSRNOP00000069221 | ENSRNOP00000074318 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma- semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). | Aldehyde dehydrogenase 18 family, member A1. | 0.880 |
| Iffo2 | Prodh1 | ENSRNOP00000069221 | ENSRNOP00000002576 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma- semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.910 |
| Iffo2 | Pycr1 | ENSRNOP00000069221 | ENSRNOP00000051832 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma- semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. | 0.575 |
| Iffo2 | Pycr2 | ENSRNOP00000069221 | ENSRNOP00000004379 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma- semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). | Pyrroline-5-carboxylate reductase 2; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (By similarity). Involved in cellular response to oxidative stress (By similarity); Belongs to the pyrroline-5-carboxylate reductase family. | 0.603 |
| Iffo2 | Pycr3 | ENSRNOP00000069221 | ENSRNOP00000071183 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma- semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). | Pyrroline-5-carboxylate reductase 3; Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. | 0.556 |
| Prodh1 | Aldh18a1 | ENSRNOP00000002576 | ENSRNOP00000020940 | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.692 |
| Prodh1 | Aldh18a1-2 | ENSRNOP00000002576 | ENSRNOP00000074318 | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | Aldehyde dehydrogenase 18 family, member A1. | 0.626 |
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