STRINGSTRING
Slc1a6 Slc1a6 Slc1a4 Slc1a4 Slc25a13 Slc25a13 Slc25a18 Slc25a18 Slc1a1 Slc1a1 Slc13a3 Slc13a3 Slc25a12 Slc25a12 Slc38a7 Slc38a7 Slc1a5 Slc1a5 Slc25a22 Slc25a22 LOC100911440 LOC100911440
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Slc1a6Excitatory amino acid transporter 4; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which [...] (561 aa)
Slc1a4Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. (529 aa)
Slc25a13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (484 aa)
Slc25a18Mitochondrial glutamate carrier 2; Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+) (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
Slc1a1Excitatory amino acid transporter 3; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorptio [...] (523 aa)
Slc13a3Solute carrier family 13 member 3; High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-6 carbon atoms, including succinate, alpha-ketoglutarate and N-acetylaspartate. The stoichiometry is probably 3 Na(+) for 1 divalent succinate. (600 aa)
Slc25a12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (655 aa)
Slc38a7Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine; Belongs to the amino acid/polyamine transporter 2 family. (463 aa)
Slc1a5Amino acid transporter. (554 aa)
Slc25a22Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
LOC100911440Solute carrier family 25 member 22. (323 aa)
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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