node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fgf8 | Gli3 | ENSRNOP00000023558 | ENSRNOP00000019396 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | GLI family zinc finger 3. | 0.477 |
Fgf8 | Nkx2-1 | ENSRNOP00000023558 | ENSRNOP00000011453 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation (By similarity). Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circad [...] | 0.488 |
Fgf8 | Pax6 | ENSRNOP00000023558 | ENSRNOP00000071013 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters (By similarity). Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains; Belongs to the paired homeobox family. | 0.657 |
Fgf8 | Six3 | ENSRNOP00000023558 | ENSRNOP00000072181 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | SIX homeobox 3. | 0.411 |
Gli3 | Fgf8 | ENSRNOP00000019396 | ENSRNOP00000023558 | GLI family zinc finger 3. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.477 |
Gli3 | Nkx2-1 | ENSRNOP00000019396 | ENSRNOP00000011453 | GLI family zinc finger 3. | Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation (By similarity). Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circad [...] | 0.418 |
Gli3 | Pax6 | ENSRNOP00000019396 | ENSRNOP00000071013 | GLI family zinc finger 3. | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters (By similarity). Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains; Belongs to the paired homeobox family. | 0.597 |
Gli3 | Ttc21b | ENSRNOP00000019396 | ENSRNOP00000007832 | GLI family zinc finger 3. | Tetratricopeptide repeat domain 21B. | 0.672 |
Gsx2 | Six3 | ENSRNOP00000003080 | ENSRNOP00000072181 | Genomic screened homeo box 2 protein. | SIX homeobox 3. | 0.454 |
Nkx2-1 | Fgf8 | ENSRNOP00000011453 | ENSRNOP00000023558 | Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation (By similarity). Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circad [...] | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.488 |
Nkx2-1 | Gli3 | ENSRNOP00000011453 | ENSRNOP00000019396 | Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation (By similarity). Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circad [...] | GLI family zinc finger 3. | 0.418 |
Nkx2-1 | Six3 | ENSRNOP00000011453 | ENSRNOP00000072181 | Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation (By similarity). Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circad [...] | SIX homeobox 3. | 0.602 |
Pax6 | Fgf8 | ENSRNOP00000071013 | ENSRNOP00000023558 | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters (By similarity). Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains; Belongs to the paired homeobox family. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.657 |
Pax6 | Gli3 | ENSRNOP00000071013 | ENSRNOP00000019396 | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters (By similarity). Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains; Belongs to the paired homeobox family. | GLI family zinc finger 3. | 0.597 |
Pax6 | Six3 | ENSRNOP00000071013 | ENSRNOP00000072181 | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters (By similarity). Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains; Belongs to the paired homeobox family. | SIX homeobox 3. | 0.828 |
Six3 | Fgf8 | ENSRNOP00000072181 | ENSRNOP00000023558 | SIX homeobox 3. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.411 |
Six3 | Gsx2 | ENSRNOP00000072181 | ENSRNOP00000003080 | SIX homeobox 3. | Genomic screened homeo box 2 protein. | 0.454 |
Six3 | Nkx2-1 | ENSRNOP00000072181 | ENSRNOP00000011453 | SIX homeobox 3. | Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation (By similarity). Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circad [...] | 0.602 |
Six3 | Pax6 | ENSRNOP00000072181 | ENSRNOP00000071013 | SIX homeobox 3. | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters (By similarity). Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains; Belongs to the paired homeobox family. | 0.828 |
Ttc21b | Gli3 | ENSRNOP00000007832 | ENSRNOP00000019396 | Tetratricopeptide repeat domain 21B. | GLI family zinc finger 3. | 0.672 |