node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cbll1 | Mettl14 | ENSRNOP00000009565 | ENSRNOP00000020574 | Cbl proto-oncogene-like 1. | Similar to KIAA1627 protein (Predicted), isoform CRA_b; Belongs to the MT-A70-like family. | 0.991 |
Cbll1 | Mettl16 | ENSRNOP00000009565 | ENSRNOP00000003750 | Cbl proto-oncogene-like 1. | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | 0.894 |
Cbll1 | Mettl3 | ENSRNOP00000009565 | ENSRNOP00000017720 | Cbl proto-oncogene-like 1. | Methyltransferase-like 3, isoform CRA_b; Belongs to the MT-A70-like family. | 0.975 |
Cbll1 | Pcif1 | ENSRNOP00000009565 | ENSRNOP00000023202 | Cbl proto-oncogene-like 1. | Similar to RIKEN cDNA F730014I05 (Predicted), isoform CRA_a. | 0.406 |
Cbll1 | Virma | ENSRNOP00000009565 | ENSRNOP00000058100 | Cbl proto-oncogene-like 1. | Vir-like m6A methyltransferase-associated. | 0.998 |
Cbll1 | Wtap | ENSRNOP00000009565 | ENSRNOP00000025936 | Cbl proto-oncogene-like 1. | WT1-associated protein. | 0.998 |
Cbll1 | Zc3h13 | ENSRNOP00000009565 | ENSRNOP00000015467 | Cbl proto-oncogene-like 1. | Zinc finger CCCH type-containing 13. | 0.995 |
Cmtr1 | Rnmt | ENSRNOP00000073460 | ENSRNOP00000022410 | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. | mRNA cap guanine-N7 methyltransferase; Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'- terminal GpppC; Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family. | 0.548 |
Cmtr1 | Trmt10c | ENSRNOP00000073460 | ENSRNOP00000002198 | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. | tRNA methyltransferase 10 homolog C; Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation. Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends. Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity. The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 a [...] | 0.429 |
Cmtr2 | Rnmt | ENSRNOP00000022952 | ENSRNOP00000022410 | Cap methyltransferase 2. | mRNA cap guanine-N7 methyltransferase; Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'- terminal GpppC; Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family. | 0.750 |
Cmtr2 | Trmt10c | ENSRNOP00000022952 | ENSRNOP00000002198 | Cap methyltransferase 2. | tRNA methyltransferase 10 homolog C; Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation. Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends. Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity. The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 a [...] | 0.501 |
Mettl14 | Cbll1 | ENSRNOP00000020574 | ENSRNOP00000009565 | Similar to KIAA1627 protein (Predicted), isoform CRA_b; Belongs to the MT-A70-like family. | Cbl proto-oncogene-like 1. | 0.991 |
Mettl14 | Mettl16 | ENSRNOP00000020574 | ENSRNOP00000003750 | Similar to KIAA1627 protein (Predicted), isoform CRA_b; Belongs to the MT-A70-like family. | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | 0.952 |
Mettl14 | Mettl3 | ENSRNOP00000020574 | ENSRNOP00000017720 | Similar to KIAA1627 protein (Predicted), isoform CRA_b; Belongs to the MT-A70-like family. | Methyltransferase-like 3, isoform CRA_b; Belongs to the MT-A70-like family. | 0.999 |
Mettl14 | Mettl8 | ENSRNOP00000020574 | ENSRNOP00000055322 | Similar to KIAA1627 protein (Predicted), isoform CRA_b; Belongs to the MT-A70-like family. | Uncharacterized protein. | 0.472 |
Mettl14 | Nsun2 | ENSRNOP00000020574 | ENSRNOP00000023641 | Similar to KIAA1627 protein (Predicted), isoform CRA_b; Belongs to the MT-A70-like family. | NOL1/NOP2/Sun domain family, member 2 (Predicted); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.741 |
Mettl14 | Pcif1 | ENSRNOP00000020574 | ENSRNOP00000023202 | Similar to KIAA1627 protein (Predicted), isoform CRA_b; Belongs to the MT-A70-like family. | Similar to RIKEN cDNA F730014I05 (Predicted), isoform CRA_a. | 0.467 |
Mettl14 | Trmt10c | ENSRNOP00000020574 | ENSRNOP00000002198 | Similar to KIAA1627 protein (Predicted), isoform CRA_b; Belongs to the MT-A70-like family. | tRNA methyltransferase 10 homolog C; Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation. Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends. Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity. The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 a [...] | 0.473 |
Mettl14 | Trmt6 | ENSRNOP00000020574 | ENSRNOP00000028893 | Similar to KIAA1627 protein (Predicted), isoform CRA_b; Belongs to the MT-A70-like family. | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.416 |
Mettl14 | Trmt61a | ENSRNOP00000020574 | ENSRNOP00000071623 | Similar to KIAA1627 protein (Predicted), isoform CRA_b; Belongs to the MT-A70-like family. | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Catalytic subunit of mRNA N(1)- methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries. | 0.411 |