| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cxcl1 | Cxcl10 | ENSRNOP00000003778 | ENSRNOP00000003649 | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | 0.975 |
| Cxcl1 | Cxcl11 | ENSRNOP00000003778 | ENSRNOP00000035380 | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | C-X-C motif chemokine. | 0.782 |
| Cxcl1 | Cxcl13 | ENSRNOP00000003778 | ENSRNOP00000034304 | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | Similar to Small inducible cytokine B13 (CXCL13) (B lymphocyte chemoattractant) (CXC chemokine BLC). | 0.853 |
| Cxcl1 | Cxcl2 | ENSRNOP00000003778 | ENSRNOP00000003745 | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | C-X-C motif chemokine 2; Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. Contributes to neutrophil activation during inflammation. | 0.970 |
| Cxcl1 | Cxcl3 | ENSRNOP00000003778 | ENSRNOP00000070985 | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | C-X-C motif chemokine 3; Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion; Belongs to the intercrine alpha (chemokine CxC) family. | 0.946 |
| Cxcl1 | Cxcl6 | ENSRNOP00000003778 | ENSRNOP00000003823 | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | C-X-C motif chemokine 5; May participate in the recruitment of inflammatory cells by injured or infected tissue. | 0.950 |
| Cxcl1 | Cxcl9 | ENSRNOP00000003778 | ENSRNOP00000003627 | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | C-X-C motif chemokine. | 0.854 |
| Cxcl1 | Pf4 | ENSRNOP00000003778 | ENSRNOP00000032276 | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | Platelet factor 4; Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation; Belongs to the intercrine alpha (chemokine CxC) family. | 0.786 |
| Cxcl1 | Ppbp | ENSRNOP00000003778 | ENSRNOP00000003794 | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | Chemokine (C-X-C motif) ligand 7, isoform CRA_b. | 0.904 |
| Cxcl10 | Cxcl1 | ENSRNOP00000003649 | ENSRNOP00000003778 | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | 0.975 |
| Cxcl10 | Cxcl11 | ENSRNOP00000003649 | ENSRNOP00000035380 | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | C-X-C motif chemokine. | 0.994 |
| Cxcl10 | Cxcl13 | ENSRNOP00000003649 | ENSRNOP00000034304 | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | Similar to Small inducible cytokine B13 (CXCL13) (B lymphocyte chemoattractant) (CXC chemokine BLC). | 0.988 |
| Cxcl10 | Cxcl2 | ENSRNOP00000003649 | ENSRNOP00000003745 | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | C-X-C motif chemokine 2; Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. Contributes to neutrophil activation during inflammation. | 0.843 |
| Cxcl10 | Cxcl3 | ENSRNOP00000003649 | ENSRNOP00000070985 | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | C-X-C motif chemokine 3; Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion; Belongs to the intercrine alpha (chemokine CxC) family. | 0.462 |
| Cxcl10 | Cxcl6 | ENSRNOP00000003649 | ENSRNOP00000003823 | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | C-X-C motif chemokine 5; May participate in the recruitment of inflammatory cells by injured or infected tissue. | 0.850 |
| Cxcl10 | Cxcl9 | ENSRNOP00000003649 | ENSRNOP00000003627 | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | C-X-C motif chemokine. | 0.998 |
| Cxcl10 | Pf4 | ENSRNOP00000003649 | ENSRNOP00000032276 | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | Platelet factor 4; Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation; Belongs to the intercrine alpha (chemokine CxC) family. | 0.992 |
| Cxcl10 | Ppbp | ENSRNOP00000003649 | ENSRNOP00000003794 | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | Chemokine (C-X-C motif) ligand 7, isoform CRA_b. | 0.986 |
| Cxcl11 | Cxcl1 | ENSRNOP00000035380 | ENSRNOP00000003778 | C-X-C motif chemokine. | Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. | 0.782 |
| Cxcl11 | Cxcl10 | ENSRNOP00000035380 | ENSRNOP00000003649 | C-X-C motif chemokine. | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] | 0.994 |