STRINGSTRING
Edem1 Edem1 Man1c1 Man1c1 Edem2 Edem2 Edem3 Edem3 Man1a2 Man1a2 Man1b1 Man1b1 Man1a1 Man1a1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Edem1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (650 aa)
Man1c1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (625 aa)
Edem2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (576 aa)
Edem3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (893 aa)
Man1a2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (640 aa)
Man1b1Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2) (By similarity); Belongs to the glycosyl hydrolase 47 family. (657 aa)
Man1a1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (746 aa)
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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