STRINGSTRING
Cldn23 Cldn23 Cldn20 Cldn20 Samt4 Samt4 Cldn34e Cldn34e Cldn3 Cldn3 Cldn7 Cldn7 Cldn10 Cldn10 LOC680190 LOC680190 LOC100362173 LOC100362173 Cldn25 Cldn25 Cldn16 Cldn16 Cldn2 Cldn2 Cldn15 Cldn15 Cldn4 Cldn4 Cldn8 Cldn8 Cldn14 Cldn14 Cldn1 Cldn1 LOC685789 LOC685789 Cldn6 Cldn6 Cldn9 Cldn9 Cldn11 Cldn11 Cldn34a Cldn34a LOC685762 LOC685762 Cldn17 Cldn17 Cldn34b Cldn34b Cldn24 Cldn24 LOC685747 LOC685747 Cldn18 Cldn18 Cldn34c4 Cldn34c4 Samt3 Samt3 Cldn19 Cldn19 Cldn22 Cldn22 Samt2 Samt2 Cldn34d Cldn34d Cldn5 Cldn5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cldn23Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (295 aa)
Cldn20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
Samt4Spermatogenesis-associated multipass transmembrane protein 4. (233 aa)
Cldn34eClaudin 34E. (212 aa)
Cldn3Claudin-3; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. (219 aa)
Cldn7Claudin-7; Plays a major role in tight junction-specific obliteration of the intercellular space; Belongs to the claudin family. (211 aa)
Cldn10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (229 aa)
LOC680190Hypothetical protein LOC680190. (208 aa)
LOC100362173RCG36365-like. (211 aa)
Cldn25Claudin 25. (228 aa)
Cldn16Claudin-16; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors (By similarity); Belongs to [...] (235 aa)
Cldn2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
Cldn15Claudin-15; Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members function as impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN15 forms tight junctions that mediate the paracellular transport of small monovalent cations along a concentration gradient, due to selective permeability for Na(+), Li(+) and K(+) ions, but selects a [...] (227 aa)
Cldn4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
Cldn8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
Cldn14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa)
Cldn1Claudin-1; Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. [...] (211 aa)
LOC685789Hypothetical protein LOC685789. (233 aa)
Cldn6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
Cldn9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
Cldn11Claudin-11; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. (207 aa)
Cldn34aClaudin 34A. (211 aa)
LOC685762Hypothetical protein LOC685762. (240 aa)
Cldn17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
Cldn34bClaudin 34B. (208 aa)
Cldn24Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
LOC685747Hypothetical protein LOC685747. (240 aa)
Cldn18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
Cldn34c4Claudin 34C4. (220 aa)
Samt3Spermatogenesis-associated multipass transmembrane protein 3. (233 aa)
Cldn19Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. (224 aa)
Cldn22Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
Samt2Uncharacterized protein. (230 aa)
Cldn34dClaudin 34D. (210 aa)
Cldn5Claudin-5; Plays a major role in tight junction-specific obliteration of the intercellular space. (218 aa)
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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