STRINGSTRING
Spred2 Spred2 Spred1 Spred1 Spry3 Spry3 Spry2 Spry2 Spry4 Spry4 Spry1 Spry1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Spred2Sprouty-related, EVH1 domain-containing protein 2; Negatively regulates Ras signaling pathways and downstream activation of MAP kinases. (425 aa)
Spred1Sprouty protein with EVH-1 domain 1, related sequence. (444 aa)
Spry3Sprouty RTK-signaling antagonist 3. (281 aa)
Spry2Sprouty RTK-signaling antagonist 2. (314 aa)
Spry4Sprouty RTK-signaling antagonist 4. (300 aa)
Spry1Sprouty RTK-signaling antagonist 1. (313 aa)
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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