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| | Nptx2 | Neuronal pentraxin-2; Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner. (432 aa) |
| | LOC100911938 | Butyrophilin-like 7. (547 aa) |
| | Trim67 | Tripartite motif-containing 67. (770 aa) |
| | Trim72 | Tripartite motif-containing protein 72; Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)- depen [...] (477 aa) |
| | Ptpru | Protein tyrosine phosphatase, receptor type, U. (1446 aa) |
| | Celsr1 | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2741 aa) |
| | Col22a1 | Collagen type XXII alpha 1 chain. (1613 aa) |
| | Btnl3 | Butyrophilin-like 3. (505 aa) |
| | Nrxn2 | Neurexin-2; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. (1715 aa) |
| | Adgrg6 | Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1193 aa) |
| | Hnrnpul1 | Heterogeneous nuclear ribonucleoprotein U-like 1 (Predicted). (859 aa) |
| | Col5a3 | Procollagen, type V, alpha 3, isoform CRA_b. (1737 aa) |
| | Cntnap1 | Contactin-associated protein 1; Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. (1381 aa) |
| | Celsr2 | Cadherin EGF LAG seven-pass G-type receptor 2; Receptor that may have an important role in cell/cell signaling during nervous system formation; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. (2919 aa) |
| | Hnrnpul2 | Heterogeneous nuclear ribonucleoprotein U-like 2. (745 aa) |
| | Lman1l | Protein ERGIC-53-like. (503 aa) |
| | Fsd2 | Fibronectin type III and SPRY domain-containing 2. (746 aa) |
| | Trim21 | Tripartite motif protein 21 (Predicted), isoform CRA_a. (471 aa) |
| | Ranbp10 | RAN-binding protein 10. (718 aa) |
| | Gas6 | Growth arrest-specific protein 6; Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses (By similarity). (674 aa) |
| | Ranbp9 | RAN-binding protein 9. (691 aa) |
| | Btn1a1 | Butyrophilin, subfamily 1, member A1. (524 aa) |
| | Cspg4 | Chondroitin sulfate proteoglycan 4; Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma ce [...] (2326 aa) |
| | Trim62 | Similar to tripartite motif-containing 62. (475 aa) |
| | Nrxn1 | Neurexin-1; Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N- terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect [...] (922 aa) |
| | Comp | Cartilage oligomeric matrix protein; May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BI [...] (755 aa) |
| | Mptx1 | Mucosal pentraxin. (219 aa) |
| | Pappa1 | Pappalysin 1. (1502 aa) |
| | Adgrv1 | Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6298 aa) |
| | Lgals7 | Galectin-7; Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release (By similarity). (136 aa) |
| | Ash2l | ASH2-like histone lysine methyltransferase complex subunit. (629 aa) |
| | Trim26 | Tripartite motif-containing protein 26; E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1. (545 aa) |
| | Celsr3 | Cadherin EGF LAG seven-pass G-type receptor 3; Receptor that may have an important role in cell/cell signaling during nervous system formation; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. (3313 aa) |
| | Herc1 | HECT and RLD domain-containing E3 ubiquitin protein ligase family member 1. (4852 aa) |
| | Svep1 | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; May play a role in the cell attachment process. (3681 aa) |
| | LOC100909752 | Procollagen, type XV, isoform CRA_a. (1345 aa) |
| | Thbs1 | Thrombospondin 1. (1152 aa) |
| | Mid2 | Midline 2 (Predicted). (705 aa) |
| | Fbxo45 | F-box/SPRY domain-containing protein 1; Component of E3 ubiquitin ligase complexes (By similarity). Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Plays a role in the regulation of neurotransmission at mature neurons. May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity). Specifically recognizes TP73, promoting its ubiquitination and degradation (By similarity); Belongs to the FBXO45/Fsn family. (283 aa) |
| | Clstn2 | Calsyntenin-2; May modulate calcium-mediated postsynaptic signals. (898 aa) |
| | Trim46 | Tripartite motif-containing protein 46; Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity and proper neuronal migration; Belongs to the TRIM/RBCC family. (561 aa) |
| | Lgals3 | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes (By simil [...] (265 aa) |
| | Trim30c | Tripartite motif-containing 30C. (514 aa) |
| | Lrba | LPS-responsive beige-like anchor protein. (2783 aa) |
| | Ptx4 | Pentraxin 4. (478 aa) |
| | Hnrnpu | Heterogeneous nuclear ribonucleoprotein U; DNA- and RNA-binding protein involved in several cellular processes such as nuclear chromatin organization, telomere-length regulation, transcription, mRNA alternative splicing and stability, Xist-mediated transcriptional silencing and mitotic cell progression. Plays a role in the regulation of interphase large-scale gene-rich chromatin organization through chromatin-associated RNAs (caRNAs) in a transcription-dependent manner, and thereby maintains genomic stability. Required for the localization of the long non-coding Xist RNA on the inactiv [...] (803 aa) |
| | Fsd1l | Fibronectin type III and SPRY domain-containing 1-like. (508 aa) |
| | Thbs3 | Thrombospondin 3. (955 aa) |
| | Rspry1 | Ring finger and SPRY domain-containing 1. (578 aa) |
| | Mid1 | E3 ubiquitin-protein ligase Midline-1; Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination; Belongs to the TRIM/RBCC family. (667 aa) |
| | Trim14 | Tripartite motif-containing 14. (440 aa) |
| | Ryr1 | Ryanodine receptor 1; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm (By similarity). Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. [...] (5012 aa) |
| | Fat1 | FAT atypical cadherin 1. (4601 aa) |
| | Rfpl4b | RING-type domain-containing protein. (260 aa) |
| | Lama5 | Laminin, alpha 5, isoform CRA_a. (3713 aa) |
| | Thbs4 | Thrombospondin-4; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via it [...] (961 aa) |
| | Spsb1 | SplA/ryanodine receptor domain and SOCS box containing 1 (Predicted). (273 aa) |
| | Npnt | Nephronectin. (613 aa) |
| | RGD1561161 | Similar to BC067074 protein. (2236 aa) |
| | Trim27 | Tripartite motif protein 27 (Predicted), isoform CRA_b. (513 aa) |
| | Crp | C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity); Belongs to the pentraxin family. (1017 aa) |
| | Malrd1 | MAM and LDL receptor class A domain-containing 1. (1679 aa) |
| | Nrp1 | Neuropilin-1; Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system (By similarity). Mediates the chemorepulsant activity of semaphorins (By similarity). Binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis (By similarity). Binding to VEGFA initiates a signaling pathway needed for motor neuron [...] (922 aa) |
| | Wdfy3 | WD repeat and FYVE domain-containing 3. (3506 aa) |
| | Egfl6 | EGF-like-domain, multiple 6. (551 aa) |
| | Lama3 | Uncharacterized protein. (2108 aa) |
| | Trim68 | Tripartite motif-containing 68. (490 aa) |
| | Lama4 | Laminin subunit alpha 4. (1773 aa) |
| | Mdga2 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. (925 aa) |
| | Rnf39 | RING finger protein 39; May play a role in prolonged long term-potentiation (LTP) maintenance. (352 aa) |
| | Trim10 | Tripartite motif-containing 10. (489 aa) |
| | Trim39 | E3 ubiquitin-protein ligase TRIM39; E3 ubiquitin-protein ligase (By similarity). May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1 (By similarity). Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21 (By similarity). Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation (By similari [...] (488 aa) |
| | Grifin | Grifin. (144 aa) |
| | Trim41 | Tripartite motif-containing 41. (628 aa) |
| | Trim7 | Tripartite motif-containing 7. (510 aa) |
| | Calr | Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis. (416 aa) |
| | Spryd4 | SPRY domain-containing protein 4. (207 aa) |
| | Nptxr | Neuronal pentraxin receptor; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. (494 aa) |
| | Ush2a | Usherin; Involved in hearing and vision as member of the USH2 complex. In the inner ear, required for the hair bundle ankle formation, which connects growing stereocilia in developing cochlear hair cells. In retina photoreceptors, the USH2 complex is required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport. (5162 aa) |
| | Nptx1 | Neuronal pentraxin-1; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. (392 aa) |
| | Clgn | Calmegin. (611 aa) |
| | Lgalsl | Galectin. (172 aa) |
| | Nell2 | Protein kinase C-binding protein NELL2; Required for neuron survival through the modulation of MAPK pathways. Involved in the regulation of hypothalamic GNRH secretion and the control of puberty. (819 aa) |
| | Ddx1 | ATP-dependent RNA helicase DDX1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double- strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 express [...] (740 aa) |
| | Trim9 | E3 ubiquitin-protein ligase TRIM9; E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions (By similarity). May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. (710 aa) |
| | Slit3 | Slit homolog 3 protein; May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors. (1404 aa) |
| | Col27a1 | Collagen alpha-1(XXVII) chain; Plays a role during the calcification of cartilage and the transition of cartilage to bone. (1855 aa) |
| | Trim47 | Similar to Tripartite motif protein 47. (642 aa) |
| | Alk | Tyrosine-protein kinase receptor. (1396 aa) |
| | Lgals2 | Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known. (130 aa) |
| | Apcs | Serum amyloid P-component; Belongs to the pentraxin family. (275 aa) |
| | Col5a1 | Collagen alpha-1(V) chain; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin (By similarity). (1840 aa) |
| | Trim35 | Tripartite motif-containing protein 35; Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth (By similarity). Implicated in the cell death mechanism (By similarity). (515 aa) |
| | Lgals1 | Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. (135 aa) |
| | Thbs2 | Thrombospondin 2. (1172 aa) |
| | Mep1a | Meprin A subunit alpha. (748 aa) |
| | Lama2 | Laminin subunit alpha 2. (3121 aa) |
| | Shbg | Sex hormone-binding globulin; Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration (By similarity). (445 aa) |
| | Clstn3 | Calsyntenin-3; May modulate calcium-mediated postsynaptic signals. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. (957 aa) |
| | Fat3 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. (4555 aa) |
| | Ptx3 | Pentraxin 3. (381 aa) |
| | Egflam | Pikachurin; Involved in both the normal retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness (By similarity). (1005 aa) |
| | Lgals5 | Galectin-5; May function in erythrocyte differentiation. (145 aa) |
| | Lgals9 | Galectin-9; Binds galactosides (By similarity). Has high affinity for the Forssman pentasaccharide (By similarity). Ligand for HAVCR2/TIM3 (By similarity). Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (By similarity). Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth (By similarity). Ligand for P4HB; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma mem [...] (354 aa) |
| | Col19a1 | Collagen type XIX alpha 1 chain. (1129 aa) |
| | Col15a1 | Collagen alpha-1(XV) chain-like. (1312 aa) |
| | Spsb4 | SplA/ryanodine receptor domain and SOCS box containing 4 (Predicted). (273 aa) |
| | Calr3 | Calreticulin. (379 aa) |
| | Col24a1 | Collagen type XXIV alpha 1 chain. (1352 aa) |
| | Triml1 | Tripartite motif family-like 1. (470 aa) |
| | Bspry | B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity. (448 aa) |
| | Spryd7 | SPRY domain-containing protein 7. (196 aa) |
| | Spsb2 | SPRY domain-containing SOCS box protein 2; Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (By similarity). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (By similarity). (264 aa) |
| | Spsb3 | SplA/ryanodine receptor domain and SOCS box containing 3 (Predicted). (391 aa) |
| | Ptprk | Receptor-like protein tyrosine phosphatase kappa. (1439 aa) |
| | Rfpl4a | Ret finger protein-like 4A. (285 aa) |
| | Lman2 | Lectin, mannose-binding 2. (358 aa) |
| | Neurl4 | G protein pathway suppressor 2 (Predicted). (1561 aa) |
| | Trim36 | Tripartite motif protein 36 (Predicted). (729 aa) |
| | Mamdc4 | Apical endosomal glycoprotein; Probably involved in the sorting and selective transport of receptors and ligands across polarized epithelia. (1215 aa) |
| | Trim6 | Tripartite motif-containing 6. (488 aa) |
| | Trim5 | Similar to 9230105E10Rik protein. (511 aa) |
| | Trim69 | E3 ubiquitin-protein ligase TRIM69; May have E3 ubiquitin-protein ligase activity. May play a role in apoptosis. (499 aa) |
| | Lama1 | Laminin subunit alpha 1. (3083 aa) |
| | Trim80 | Tripartite motif protein 80. (642 aa) |
| | Nrxn3 | Neurexin-3; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. (430 aa) |
| | Trim17 | E3 ubiquitin-protein ligase TRIM17; May function as a ubiquitin E3 ligase. Belongs to the TRIM/RBCC family. (500 aa) |
| | Ryr2 | Ryanodine receptor 2; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development (By similarity); Belongs to t [...] (4938 aa) |
| | Col16a1 | Collagen type XVI alpha 1 chain. (1618 aa) |
| | Trim31 | Tripartite motif protein 31 (Predicted). (507 aa) |
| | Btn2a2 | Butyrophilin, subfamily 2, member A2. (523 aa) |
| | Lgals12 | Galectin. (314 aa) |
| | Fat2 | Protocadherin Fat 2; Involved in the regulation of cell migration. May be involved in mediating the organization of the parallel fibers of granule cells during cerebellar development. (4351 aa) |
| | Adgrd1 | Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (903 aa) |
| | Ptprm | Protein tyrosine phosphatase, receptor type, M. (1486 aa) |
| | Nbeal2 | Neurobeachin-like 2. (2729 aa) |
| | Nell1 | Protein kinase C-binding protein NELL1; Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization (By similarity). (810 aa) |
| | Trim25 | Tripartite motif-containing 25. (643 aa) |
| | Spryd3 | SPRY domain-containing 3. (442 aa) |
| | Trim34 | Tripartite motif-containing 34. (486 aa) |
| | Agrn | Agrin C-terminal 110 kDa subunit; [Isoform 1]: heparan sulfate basal lamina glycoprotein that plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ) and directs key events in postsynaptic differentiation. This neuron-specific (z+) isoform is a component of the AGRN-LRP4 receptor complex that induces the phosphorylation and activation of MUSK. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Calcium [...] (1941 aa) |
| | Col20a1 | Collagen type XX alpha 1 chain. (1362 aa) |
| | Rnf123 | E3 ubiquitin-protein ligase RNF123; Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Promotes the ubiquitination and proteasome- mediated degradation of CDKN1B which is the cyclin-dependent kinase inhibitor at the G0-G1 transition of the cell cycle. Functions also as an inhibitor of innate antiviral signaling mediated by DDX58 and IFIH1 independently of its E3 ligase activity. Interacts with the N-terminal CARD domains of DDX58 and IFIH1 and competes with the downstream adapter MAVS. (1318 aa) |
| | Trim58 | Tripartite motif-containing 58. (485 aa) |
| | Col11a2 | Procollagen, type XI, alpha 2 (Mapped). (1650 aa) |
| | Col18a1 | Procollagen, type XVIII, alpha 1, isoform CRA_a. (1311 aa) |
| | Trim65 | Tripartite motif-containing 65. (592 aa) |
| | Lgals4 | Galectin-4; Galectin that binds lactose and a related range of sugars. (324 aa) |
| | Clstn1 | Soluble Alc-alpha; Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. As intracellular fragment AlcICD, suppresses APBB1-dependent tran [...] (952 aa) |
| | Nrp2 | Neuropilin-2; High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF; Belongs to the neuropilin family. (925 aa) |
| | Trim43a | Tripartite motif-containing 43A. (451 aa) |
| | LOC304725 | Contactin-associated protein like 5-2; May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication; Belongs to the neurexin family. (1292 aa) |
| | Btnl10 | Butyrophilin-like 10. (453 aa) |
| | Tmprss15 | Transmembrane serine protease 15; Belongs to the peptidase S1 family. (859 aa) |
| | Ptprt | Protein tyrosine phosphatase, receptor type, T (Predicted). (1269 aa) |
| | Canx | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] (591 aa) |
| | D4AA49_RAT | Uncharacterized protein. (951 aa) |
| | Mdga1 | MAM domain-containing glycosylphosphatidylinositol anchor protein 1; Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2. (943 aa) |
| | Lgals8 | Galectin-8; Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruse [...] (316 aa) |
| | Lman2l | Lectin, mannose-binding 2-like (Predicted), isoform CRA_c. (349 aa) |
| | Cntnap4 | Contactin-associated protein 4. (1241 aa) |
| | Col11a1 | Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. (1804 aa) |
| | Cntnap5c | Contactin-associated protein like 5-4; May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication; Belongs to the neurexin family. (1279 aa) |
| | Calr4 | Calreticulin. (439 aa) |
| | Trim16 | Tripartite motif-containing 16. (557 aa) |
| | Col14a1 | Collagen type XIV alpha 1 chain. (1794 aa) |
| | Mep1b | Meprin A subunit beta; Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components. (704 aa) |
| | Cmya5 | Cardiomyopathy-associated 5. (3943 aa) |
| | Pros1 | Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. (675 aa) |
| | Btnl9 | Butyrophilin-like 9. (529 aa) |
| | Btnl8 | Butyrophilin-like 8. (588 aa) |
| | Cntnap5b | Contactin-associated protein like 5-3; May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication; Belongs to the neurexin family. (1307 aa) |
| | Trim11 | E3 ubiquitin-protein ligase TRIM11; E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation [...] (467 aa) |
| | Mamdc2 | MAM domain containing 2. (642 aa) |
| | Crb1 | Crumbs homolog 1 (Drosophila) (Predicted). (1407 aa) |
| | Tspear | Thrombospondin-type laminin G domain and EAR repeats. (571 aa) |
| | Fat4 | FAT atypical cadherin 4. (4981 aa) |
| | Trim50 | E3 ubiquitin-protein ligase TRIM50; E3 ubiquitin-protein ligase that ubiquitinates Beclin-1/BECN1 in a 'Lys-63'-dependent manner enhancing its binding to ULK1. In turn, promotes starvation-induced autophagy activation. Interacts also with p62/SQSTM1 protein and thereby induces the formation and the autophagy clearance of aggresome-associated polyubiquitinated proteins through HDAC6 interaction; Belongs to the TRIM/RBCC family. (484 aa) |
| | Lman1 | Protein ERGIC-53; Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins (By similarity). (517 aa) |
| | Crb2 | Crumbs cell polarity complex component 2. (1283 aa) |
| | Slit1 | Slit homolog 1 protein; Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb (By similarity). (1530 aa) |
| | Triml2 | Tripartite motif family-like 2. (430 aa) |
| | Ermap | Erythroblast membrane-associated protein (Scianna blood group). (591 aa) |
| | Fsd1 | Similar to fibronectin type 3 and SPRY domain-containing protein, isoform CRA_a. (496 aa) |
| | Btn3a2 | Similar to butyrophilin-like 7. (589 aa) |
