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Itga8 Itga8 Itga9 Itga9 Itga11 Itga11 Itga4 Itga4 Itga6 Itga6 Itgav Itgav Itgae Itgae Itga1 Itga1 Itgad Itgad Itga2b Itga2b Itgax Itgax Itga2 Itga2 Itga5 Itga5 Itga3 Itga3 Itga7 Itga7 Itga10 Itga10 Itgal Itgal Gpld1 Gpld1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Itga8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
Itga9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1036 aa)
Itga11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1088 aa)
Itga4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1036 aa)
Itga6Integrin, alpha 6, isoform CRA_a; Belongs to the integrin alpha chain family. (1073 aa)
ItgavIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1052 aa)
ItgaeIntegrin subunit alpha E; Belongs to the integrin alpha chain family. (1169 aa)
Itga1Integrin alpha-1; Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth (By similarity). (1180 aa)
ItgadIntegrin alpha-D; Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood (By similarity). (1161 aa)
Itga2bIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1034 aa)
ItgaxIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1182 aa)
Itga2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1178 aa)
Itga5Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. (1099 aa)
Itga3Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. (1067 aa)
Itga7Integrin alpha-7 70 kDa form; Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. Involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells (By similarity). Acts as Schwann cell receptor [...] (1160 aa)
Itga10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1167 aa)
ItgalIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1161 aa)
Gpld1Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane. (843 aa)
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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