(6 nodes) Importin subunit alpha network (Rattus norvegicus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	Kpna7	Importin subunit alpha; Functions in nuclear protein import. (500 aa)
	Kpna6	Importin subunit alpha; Functions in nuclear protein import. (541 aa)
	Kpna4	Importin subunit alpha; Functions in nuclear protein import. (521 aa)
	Kpna3	Importin subunit alpha; Functions in nuclear protein import. (521 aa)
	Kpna5	Importin subunit alpha-6; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...] (518 aa)
	Kpna1	Importin subunit alpha-5; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...] (538 aa)

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Kpna1	Kpna3	ENSRNOP00000071569	ENSRNOP00000032371	Importin subunit alpha-5; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...]	Importin subunit alpha; Functions in nuclear protein import.	0.948
Kpna1	Kpna4	ENSRNOP00000071569	ENSRNOP00000014384	Importin subunit alpha-5; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...]	Importin subunit alpha; Functions in nuclear protein import.	0.949
Kpna1	Kpna6	ENSRNOP00000071569	ENSRNOP00000000139	Importin subunit alpha-5; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...]	Importin subunit alpha; Functions in nuclear protein import.	0.813
Kpna1	Kpna7	ENSRNOP00000071569	ENSRNOP00000068379	Importin subunit alpha-5; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...]	Importin subunit alpha; Functions in nuclear protein import.	0.788
Kpna3	Kpna1	ENSRNOP00000032371	ENSRNOP00000071569	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha-5; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...]	0.948
Kpna3	Kpna4	ENSRNOP00000032371	ENSRNOP00000014384	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.984
Kpna3	Kpna6	ENSRNOP00000032371	ENSRNOP00000000139	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.816
Kpna3	Kpna7	ENSRNOP00000032371	ENSRNOP00000068379	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.763
Kpna4	Kpna1	ENSRNOP00000014384	ENSRNOP00000071569	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha-5; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...]	0.949
Kpna4	Kpna3	ENSRNOP00000014384	ENSRNOP00000032371	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.984
Kpna4	Kpna6	ENSRNOP00000014384	ENSRNOP00000000139	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.793
Kpna4	Kpna7	ENSRNOP00000014384	ENSRNOP00000068379	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.764
Kpna6	Kpna1	ENSRNOP00000000139	ENSRNOP00000071569	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha-5; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...]	0.813
Kpna6	Kpna3	ENSRNOP00000000139	ENSRNOP00000032371	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.816
Kpna6	Kpna4	ENSRNOP00000000139	ENSRNOP00000014384	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.793
Kpna6	Kpna7	ENSRNOP00000000139	ENSRNOP00000068379	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.767
Kpna7	Kpna1	ENSRNOP00000068379	ENSRNOP00000071569	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha-5; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...]	0.788
Kpna7	Kpna3	ENSRNOP00000068379	ENSRNOP00000032371	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.763
Kpna7	Kpna4	ENSRNOP00000068379	ENSRNOP00000014384	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.764
Kpna7	Kpna6	ENSRNOP00000068379	ENSRNOP00000000139	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.767

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