node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bgn | Col11a1 | ENSRNOP00000072449 | ENSRNOP00000061595 | Biglycan; May be involved in collagen fiber assembly. | Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. | 0.518 |
Bgn | Col2a1 | ENSRNOP00000072449 | ENSRNOP00000071077 | Biglycan; May be involved in collagen fiber assembly. | Collagen alpha-1(II) chain; Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. | 0.631 |
Bgn | Comp | ENSRNOP00000072449 | ENSRNOP00000067037 | Biglycan; May be involved in collagen fiber assembly. | Cartilage oligomeric matrix protein; May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BI [...] | 0.694 |
Bgn | Dcn | ENSRNOP00000072449 | ENSRNOP00000006070 | Biglycan; May be involved in collagen fiber assembly. | Decorin; May affect the rate of fibrils formation (By similarity). May be implicated in the dilatation of the rat cervix. | 0.973 |
Bgn | Fmod | ENSRNOP00000072449 | ENSRNOP00000004382 | Biglycan; May be involved in collagen fiber assembly. | Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | 0.944 |
Bgn | Hyal4 | ENSRNOP00000072449 | ENSRNOP00000072978 | Biglycan; May be involved in collagen fiber assembly. | Hyaluronidase. | 0.425 |
Bgn | Hyal5 | ENSRNOP00000072449 | ENSRNOP00000057222 | Biglycan; May be involved in collagen fiber assembly. | Hyaluronidase. | 0.418 |
Bgn | Hyal6 | ENSRNOP00000072449 | ENSRNOP00000009405 | Biglycan; May be involved in collagen fiber assembly. | Hyaluronidase. | 0.418 |
Bgn | Lox | ENSRNOP00000072449 | ENSRNOP00000065314 | Biglycan; May be involved in collagen fiber assembly. | Protein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity); Belongs to the lysyl oxidase family. | 0.667 |
Bgn | Mmp13 | ENSRNOP00000072449 | ENSRNOP00000011507 | Biglycan; May be involved in collagen fiber assembly. | Collagenase 3; Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bon [...] | 0.559 |
Bgn | Mmp3 | ENSRNOP00000072449 | ENSRNOP00000012310 | Biglycan; May be involved in collagen fiber assembly. | Stromelysin-1; Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase; Belongs to the peptidase M10A family. | 0.585 |
Col11a1 | Bgn | ENSRNOP00000061595 | ENSRNOP00000072449 | Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. | Biglycan; May be involved in collagen fiber assembly. | 0.518 |
Col11a1 | Col2a1 | ENSRNOP00000061595 | ENSRNOP00000071077 | Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. | Collagen alpha-1(II) chain; Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. | 0.912 |
Col11a1 | Col9a2 | ENSRNOP00000061595 | ENSRNOP00000049994 | Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. | Procollagen, type IX, alpha 2 (Predicted). | 0.667 |
Col11a1 | Col9a3 | ENSRNOP00000061595 | ENSRNOP00000013105 | Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. | Collagen type IX alpha 3 chain. | 0.629 |
Col11a1 | Comp | ENSRNOP00000061595 | ENSRNOP00000067037 | Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. | Cartilage oligomeric matrix protein; May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BI [...] | 0.466 |
Col11a1 | Fmod | ENSRNOP00000061595 | ENSRNOP00000004382 | Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. | Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | 0.545 |
Col11a1 | Mmp13 | ENSRNOP00000061595 | ENSRNOP00000011507 | Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. | Collagenase 3; Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bon [...] | 0.498 |
Col11a1 | Mmp3 | ENSRNOP00000061595 | ENSRNOP00000012310 | Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. | Stromelysin-1; Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase; Belongs to the peptidase M10A family. | 0.427 |
Col2a1 | Bgn | ENSRNOP00000071077 | ENSRNOP00000072449 | Collagen alpha-1(II) chain; Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. | Biglycan; May be involved in collagen fiber assembly. | 0.631 |