8 items (Rattus norvegicus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	Bub1	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). (1059 aa)
	Apaf1	Apoptotic protease-activating factor 1; Regulates programmed cell death; necessary for normal brain development. Participates with pro-caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP (By similarity). (1249 aa)
	LOC100360940	Diablo-like. (253 aa)
	Cycs	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	Casp9	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. (454 aa)
	Kcnj11	ATP-sensitive inward rectifier potassium channel 11; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smo [...] (390 aa)
	Htra2	HtrA serine peptidase 2. (458 aa)
	Diablo	Diablo homolog (Drosophila), isoform CRA_b. (237 aa)

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Apaf1	Casp9	ENSRNOP00000010869	ENSRNOP00000017972	Apoptotic protease-activating factor 1; Regulates programmed cell death; necessary for normal brain development. Participates with pro-caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP (By similarity).	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family.	0.999
Apaf1	Cycs	ENSRNOP00000010869	ENSRNOP00000014058	Apoptotic protease-activating factor 1; Regulates programmed cell death; necessary for normal brain development. Participates with pro-caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP (By similarity).	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.999
Apaf1	Diablo	ENSRNOP00000010869	ENSRNOP00000046476	Apoptotic protease-activating factor 1; Regulates programmed cell death; necessary for normal brain development. Participates with pro-caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP (By similarity).	Diablo homolog (Drosophila), isoform CRA_b.	0.972
Apaf1	Htra2	ENSRNOP00000010869	ENSRNOP00000030076	Apoptotic protease-activating factor 1; Regulates programmed cell death; necessary for normal brain development. Participates with pro-caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP (By similarity).	HtrA serine peptidase 2.	0.821
Apaf1	LOC100360940	ENSRNOP00000010869	ENSRNOP00000011308	Apoptotic protease-activating factor 1; Regulates programmed cell death; necessary for normal brain development. Participates with pro-caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP (By similarity).	Diablo-like.	0.785
Bub1	Casp9	ENSRNOP00000042114	ENSRNOP00000017972	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family.	0.441
Casp9	Apaf1	ENSRNOP00000017972	ENSRNOP00000010869	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Regulates programmed cell death; necessary for normal brain development. Participates with pro-caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP (By similarity).	0.999
Casp9	Bub1	ENSRNOP00000017972	ENSRNOP00000042114	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family.	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	0.441
Casp9	Cycs	ENSRNOP00000017972	ENSRNOP00000014058	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family.	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.999
Casp9	Diablo	ENSRNOP00000017972	ENSRNOP00000046476	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family.	Diablo homolog (Drosophila), isoform CRA_b.	0.955
Casp9	Htra2	ENSRNOP00000017972	ENSRNOP00000030076	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family.	HtrA serine peptidase 2.	0.674
Casp9	LOC100360940	ENSRNOP00000017972	ENSRNOP00000011308	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family.	Diablo-like.	0.715
Cycs	Apaf1	ENSRNOP00000014058	ENSRNOP00000010869	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Apoptotic protease-activating factor 1; Regulates programmed cell death; necessary for normal brain development. Participates with pro-caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP (By similarity).	0.999
Cycs	Casp9	ENSRNOP00000014058	ENSRNOP00000017972	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family.	0.999
Cycs	Diablo	ENSRNOP00000014058	ENSRNOP00000046476	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Diablo homolog (Drosophila), isoform CRA_b.	0.968
Cycs	Htra2	ENSRNOP00000014058	ENSRNOP00000030076	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	HtrA serine peptidase 2.	0.972
Cycs	LOC100360940	ENSRNOP00000014058	ENSRNOP00000011308	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Diablo-like.	0.603
Diablo	Apaf1	ENSRNOP00000046476	ENSRNOP00000010869	Diablo homolog (Drosophila), isoform CRA_b.	Apoptotic protease-activating factor 1; Regulates programmed cell death; necessary for normal brain development. Participates with pro-caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP (By similarity).	0.972
Diablo	Casp9	ENSRNOP00000046476	ENSRNOP00000017972	Diablo homolog (Drosophila), isoform CRA_b.	Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family.	0.955
Diablo	Cycs	ENSRNOP00000046476	ENSRNOP00000014058	Diablo homolog (Drosophila), isoform CRA_b.	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.968

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