Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| D4A7L5_RAT | Hltf | ENSRNOP00000047101 | ENSRNOP00000069487 | Small ubiquitin-related modifier. | Helicase-like transcription factor. | 0.512 |
| D4A7L5_RAT | Pcna | ENSRNOP00000047101 | ENSRNOP00000028887 | Small ubiquitin-related modifier. | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.765 |
| D4A7L5_RAT | Rad18 | ENSRNOP00000047101 | ENSRNOP00000063400 | Small ubiquitin-related modifier. | RAD18 E3 ubiquitin protein ligase. | 0.482 |
| D4A7L5_RAT | Uba1 | ENSRNOP00000047101 | ENSRNOP00000033950 | Small ubiquitin-related modifier. | Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites. | 0.668 |
| Hltf | D4A7L5_RAT | ENSRNOP00000069487 | ENSRNOP00000047101 | Helicase-like transcription factor. | Small ubiquitin-related modifier. | 0.512 |
| Hltf | Pcna | ENSRNOP00000069487 | ENSRNOP00000028887 | Helicase-like transcription factor. | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.939 |
| Hltf | Rad18 | ENSRNOP00000069487 | ENSRNOP00000063400 | Helicase-like transcription factor. | RAD18 E3 ubiquitin protein ligase. | 0.987 |
| Hltf | Sumo4 | ENSRNOP00000069487 | ENSRNOP00000044856 | Helicase-like transcription factor. | Small ubiquitin-related modifier. | 0.510 |
| Pcna | D4A7L5_RAT | ENSRNOP00000028887 | ENSRNOP00000047101 | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | Small ubiquitin-related modifier. | 0.765 |
| Pcna | Hltf | ENSRNOP00000028887 | ENSRNOP00000069487 | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | Helicase-like transcription factor. | 0.939 |
| Pcna | Rad18 | ENSRNOP00000028887 | ENSRNOP00000063400 | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | RAD18 E3 ubiquitin protein ligase. | 0.988 |
| Pcna | Sumo4 | ENSRNOP00000028887 | ENSRNOP00000044856 | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | Small ubiquitin-related modifier. | 0.774 |
| Rad18 | D4A7L5_RAT | ENSRNOP00000063400 | ENSRNOP00000047101 | RAD18 E3 ubiquitin protein ligase. | Small ubiquitin-related modifier. | 0.482 |
| Rad18 | Hltf | ENSRNOP00000063400 | ENSRNOP00000069487 | RAD18 E3 ubiquitin protein ligase. | Helicase-like transcription factor. | 0.987 |
| Rad18 | Pcna | ENSRNOP00000063400 | ENSRNOP00000028887 | RAD18 E3 ubiquitin protein ligase. | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.988 |
| Rad18 | Sumo4 | ENSRNOP00000063400 | ENSRNOP00000044856 | RAD18 E3 ubiquitin protein ligase. | Small ubiquitin-related modifier. | 0.480 |
| Sumo4 | Hltf | ENSRNOP00000044856 | ENSRNOP00000069487 | Small ubiquitin-related modifier. | Helicase-like transcription factor. | 0.510 |
| Sumo4 | Pcna | ENSRNOP00000044856 | ENSRNOP00000028887 | Small ubiquitin-related modifier. | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.774 |
| Sumo4 | Rad18 | ENSRNOP00000044856 | ENSRNOP00000063400 | Small ubiquitin-related modifier. | RAD18 E3 ubiquitin protein ligase. | 0.480 |
| Sumo4 | Uba1 | ENSRNOP00000044856 | ENSRNOP00000033950 | Small ubiquitin-related modifier. | Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites. | 0.673 |
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