node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Alb | Lmnb1 | ENSRNOP00000003921 | ENSRNOP00000019351 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. | 0.633 |
Alb | Npm1 | ENSRNOP00000003921 | ENSRNOP00000006591 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Nucleophosmin; Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. M [...] | 0.511 |
Kpna2 | Kpna3 | ENSRNOP00000020795 | ENSRNOP00000032371 | Importin subunit alpha; Functions in nuclear protein import. | Importin subunit alpha; Functions in nuclear protein import. | 0.914 |
Kpna2 | Kpna4 | ENSRNOP00000020795 | ENSRNOP00000014384 | Importin subunit alpha; Functions in nuclear protein import. | Importin subunit alpha; Functions in nuclear protein import. | 0.914 |
Kpna2 | Lmnb1 | ENSRNOP00000020795 | ENSRNOP00000019351 | Importin subunit alpha; Functions in nuclear protein import. | Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. | 0.537 |
Kpna2 | Rcc1 | ENSRNOP00000020795 | ENSRNOP00000074333 | Importin subunit alpha; Functions in nuclear protein import. | Regulator of chromosome condensation 1. | 0.816 |
Kpna3 | Kpna2 | ENSRNOP00000032371 | ENSRNOP00000020795 | Importin subunit alpha; Functions in nuclear protein import. | Importin subunit alpha; Functions in nuclear protein import. | 0.914 |
Kpna3 | Kpna4 | ENSRNOP00000032371 | ENSRNOP00000014384 | Importin subunit alpha; Functions in nuclear protein import. | Importin subunit alpha; Functions in nuclear protein import. | 0.984 |
Kpna3 | Lmnb1 | ENSRNOP00000032371 | ENSRNOP00000019351 | Importin subunit alpha; Functions in nuclear protein import. | Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. | 0.549 |
Kpna3 | Rcc1 | ENSRNOP00000032371 | ENSRNOP00000074333 | Importin subunit alpha; Functions in nuclear protein import. | Regulator of chromosome condensation 1. | 0.934 |
Kpna4 | Kpna2 | ENSRNOP00000014384 | ENSRNOP00000020795 | Importin subunit alpha; Functions in nuclear protein import. | Importin subunit alpha; Functions in nuclear protein import. | 0.914 |
Kpna4 | Kpna3 | ENSRNOP00000014384 | ENSRNOP00000032371 | Importin subunit alpha; Functions in nuclear protein import. | Importin subunit alpha; Functions in nuclear protein import. | 0.984 |
Kpna4 | Lmnb1 | ENSRNOP00000014384 | ENSRNOP00000019351 | Importin subunit alpha; Functions in nuclear protein import. | Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. | 0.528 |
Kpna4 | Rcc1 | ENSRNOP00000014384 | ENSRNOP00000074333 | Importin subunit alpha; Functions in nuclear protein import. | Regulator of chromosome condensation 1. | 0.960 |
Lbr | Lmnb1 | ENSRNOP00000069002 | ENSRNOP00000019351 | Delta(14)-sterol reductase LBR; Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis (By similarity). Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation (By similarity). Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation (By similarity). Anchors the lamina and the heterochromatin to the inner nuclear [...] | Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. | 0.992 |
Lmnb1 | Alb | ENSRNOP00000019351 | ENSRNOP00000003921 | Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.633 |
Lmnb1 | Kpna2 | ENSRNOP00000019351 | ENSRNOP00000020795 | Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. | Importin subunit alpha; Functions in nuclear protein import. | 0.537 |
Lmnb1 | Kpna3 | ENSRNOP00000019351 | ENSRNOP00000032371 | Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. | Importin subunit alpha; Functions in nuclear protein import. | 0.549 |
Lmnb1 | Kpna4 | ENSRNOP00000019351 | ENSRNOP00000014384 | Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. | Importin subunit alpha; Functions in nuclear protein import. | 0.528 |
Lmnb1 | Lbr | ENSRNOP00000019351 | ENSRNOP00000069002 | Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. | Delta(14)-sterol reductase LBR; Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis (By similarity). Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation (By similarity). Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation (By similarity). Anchors the lamina and the heterochromatin to the inner nuclear [...] | 0.992 |