STRINGSTRING
LOC100909524 LOC100909524 Agt Agt Serpinb6a Serpinb6a Serpine3 Serpine3 Serpinb3 Serpinb3 LOC100909605 LOC100909605 RGD1565462 RGD1565462 LOC299277 LOC299277 Serpina1f Serpina1f Serpinb1a Serpinb1a Serpinb6b Serpinb6b Serpina10 Serpina10 LOC100911107 LOC100911107 Serpina6 Serpina6 Serpina9 Serpina9 Serpina12 Serpina12 Serpina4 Serpina4 Serpina5 Serpina5 Serpina3m Serpina3m Serpini2 Serpini2 Serpina3c Serpina3c Serpini1 Serpini1 Serpina7 Serpina7 Serpine2 Serpine2 Serpinb9 Serpinb9 LOC102553010 LOC102553010 Serpinb1b Serpinb1b Serpinh1 Serpinh1 Serpinf2 Serpinf2 Serpinf1 Serpinf1 Serpinc1 Serpinc1 Serpinb5 Serpinb5 Serpinb11 Serpinb11 Serpinb3a Serpinb3a Serpinb7 Serpinb7 Serpinb2 Serpinb2 Serpinb10 Serpinb10 Serpinb8 Serpinb8 Serpine1 Serpine1 Serpina1 Serpina1 Serpind1 Serpind1 Serpinb12 Serpinb12 Serping1 Serping1 Serpina11 Serpina11 Serpinb9d Serpinb9d Serpinb13 Serpinb13 Serpina16 Serpina16 LOC299282 LOC299282
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100909524Serpin family A member 10. (436 aa)
AgtAngiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. (477 aa)
Serpinb6aSerine (Or cysteine) peptidase inhibitor, clade B, member 6a, isoform CRA_a; Belongs to the serpin family. (379 aa)
Serpine3Serpin family E member 3; Belongs to the serpin family. (402 aa)
Serpinb3Serpin family B member 3; Belongs to the serpin family. (326 aa)
LOC100909605Serine protease inhibitor A3F-like; Belongs to the serpin family. (410 aa)
RGD1565462Serine protease inhibitor A3F-like. (410 aa)
LOC299277Similar to serine (or cysteine) peptidase inhibitor, clade A, member 3B; Belongs to the serpin family. (419 aa)
Serpina1fSerine (or cysteine) peptidase inhibitor, clade A, member 1F; Belongs to the serpin family. (412 aa)
Serpinb1aLeukocyte elastase inhibitor A; Regulates the activity of the neutrophil proteases. (379 aa)
Serpinb6bSerine (or cysteine) peptidase inhibitor, clade B, member 6b; Belongs to the serpin family. (376 aa)
Serpina10Protein Z-dependent protease inhibitor; Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors (By similarity); Belongs to the serpin family. (436 aa)
LOC100911107Leukocyte elastase inhibitor A-like; Belongs to the serpin family. (373 aa)
Serpina6Corticosteroid-binding globulin; Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. Belongs to the serpin family. (396 aa)
Serpina9Serpin family A member 9; Belongs to the serpin family. (417 aa)
Serpina12Serpin A12; Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. Belongs to the serpin family. (414 aa)
Serpina4Serine (Or cysteine) proteinase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 4; Belongs to the serpin family. (423 aa)
Serpina5Serine (Or cysteine) peptidase inhibitor, clade A, member 5; Belongs to the serpin family. (442 aa)
Serpina3mSerine protease inhibitor A3M. (419 aa)
Serpini2Serine (Or cysteine) peptidase inhibitor, clade I, member 2; Belongs to the serpin family. (405 aa)
Serpina3cSerine protease inhibitor A3K; Binds to and inhibits kallikreins. Inhibits trypsin but not chymotrypsin or elastase. (416 aa)
Serpini1Neuroserpin; Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator. (410 aa)
Serpina7Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. (426 aa)
Serpine2Glia-derived nexin; Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin; Belongs to the serpin family. (397 aa)
Serpinb9Serine (Or cysteine) peptidase inhibitor, clade B, member 9; Belongs to the serpin family. (374 aa)
LOC102553010Leukocyte elastase inhibitor A-like; Belongs to the serpin family. (323 aa)
Serpinb1bSerine (or cysteine) peptidase inhibitor, clade B, member 1b; Belongs to the serpin family. (378 aa)
Serpinh1Serpin H1; Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. (417 aa)
Serpinf2Serpin family F member 2; Belongs to the serpin family. (554 aa)
Serpinf1Serine (Or cysteine) peptidase inhibitor, clade F, member 1, isoform CRA_c; Belongs to the serpin family. (418 aa)
Serpinc1Serine (Or cysteine) peptidase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family. (465 aa)
Serpinb5Serpin B5; Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity (By similarity). (375 aa)
Serpinb11Serine (Or cysteine) peptidase inhibitor, clade B (Ovalbumin), member 11 (Predicted); Belongs to the serpin family. (388 aa)
Serpinb3aSerine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; Belongs to the serpin family. (387 aa)
Serpinb7Serine (Or cysteine) proteinase inhibitor, clade B, member 7; Belongs to the serpin family. (380 aa)
Serpinb2Plasminogen activator inhibitor 2 type A; Inhibits urokinase-type plasminogen activator; Belongs to the serpin family. Ov-serpin subfamily. (416 aa)
Serpinb10Serpin B10; Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus (By similarity). Inhibits plasmin. (397 aa)
Serpinb8Serine (Or cysteine) peptdiase inhibitor, clade B, member 8 (Predicted); Belongs to the serpin family. (375 aa)
Serpine1Plasminogen activator inhibitor 1; Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase- type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. I [...] (402 aa)
Serpina1Alpha-1-antiproteinase; Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin; Belongs to the serpin family. (415 aa)
Serpind1Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT) (By similarity). (511 aa)
Serpinb12Serpin family B member 12; Belongs to the serpin family. (421 aa)
Serping1Plasma protease C1 inhibitor; Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein (By similarity). (504 aa)
Serpina11Serpin A11; Belongs to the serpin family. (462 aa)
Serpinb9dSerine (Or cysteine) proteinase inhibitor, clade B, member 9e (Predicted); Belongs to the serpin family. (337 aa)
Serpinb13Serine (Or cysteine) peptidase inhibitor, clade B (Ovalbumin), member 13 (Predicted); Belongs to the serpin family. (389 aa)
Serpina16Serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16; Belongs to the serpin family. (415 aa)
LOC299282Serine protease inhibitor A3N; Belongs to the serpin family. (699 aa)
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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