56 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TTC8	Tetratricopeptide repeat domain 8. (515 aa)
	KLHL14	Kelch like family member 14. (629 aa)
	BBS9	Bardet-Biedl syndrome 9. (887 aa)
	BBS7	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
	KLHL8	Kelch like family member 8. (619 aa)
	KLHL18	Kelch like family member 18. (579 aa)
	H0UYD4_CAVPO	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (552 aa)
	TTC13	Tetratricopeptide repeat domain 13. (845 aa)
	KLHL42	Kelch like family member 42. (479 aa)
	BBS2	Bardet-Biedl syndrome 2 protein homolog. (721 aa)
	NOLC1	Nucleolar and coiled-body phosphoprotein 1. (732 aa)
	KLHL41	Kelch like family member 41. (606 aa)
	LOC100716676	TPR_REGION domain-containing protein. (567 aa)
	ARL6	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	SLC27A2	Solute carrier family 27 member 2. (619 aa)
	KLHL17	Kelch like family member 17. (638 aa)
	LZTFL1	Leucine zipper transcription factor like 1. (299 aa)
	KLHL21	Kelch like family member 21. (596 aa)
	LOC100730225	BTB domain-containing protein. (659 aa)
	SLC27A3	Solute carrier family 27 member 3. (664 aa)
	IPP	Intracisternal A particle-promoted polypeptide. (584 aa)
	KLHL35	Kelch like family member 35. (493 aa)
	KIFC2	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (774 aa)
	LOC100727533	BTB domain-containing protein. (458 aa)
	KLHL1	Kelch like family member 1. (638 aa)
	NUB1	Negative regulator of ubiquitin like proteins 1. (628 aa)
	KCTD8	Potassium channel tetramerization domain containing 8. (321 aa)
	KBTBD8	Kelch repeat and BTB domain containing 8. (600 aa)
	KLHL25	Kelch like family member 25. (589 aa)
	KLHL22	Kelch like family member 22. (639 aa)
	BTBD17	BTB domain containing 17. (478 aa)
	KBTBD4	Kelch repeat and BTB domain containing 4. (535 aa)
	Ptma	Uncharacterized protein. (94 aa)
	ENC1	Ectodermal-neural cortex 1. (589 aa)
	KLHL40	Kelch like family member 40. (624 aa)
	LOC100713869	BTB domain-containing protein. (458 aa)
	KLHL11	Kelch like family member 11. (706 aa)
	KCTD6	Potassium channel tetramerization domain containing 6. (238 aa)
	DOCK6	Dedicator of cytokinesis 6; Belongs to the DOCK family. (2063 aa)
	Bbs1	BBS1 domain-containing protein. (593 aa)
	BTBD6	BTB domain containing 6. (521 aa)
	TTC32	Tetratricopeptide repeat domain 32. (153 aa)
	ENSCPOP00000021870	Uncharacterized protein. (70 aa)
	NFE2L3	Nuclear factor, erythroid 2 like 3. (675 aa)
	KLHL5	Kelch like family member 5. (709 aa)
	KLHL10	Kelch like family member 10. (608 aa)
	KCTD12	Potassium channel tetramerization domain containing 12. (325 aa)
	GAN	Gigaxonin. (597 aa)
	RHOBTB1	Rho related BTB domain containing 1. (696 aa)
	BBS5	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...] (341 aa)
	KCTD7	Potassium channel tetramerization domain containing 7. (289 aa)
	KLHL34	Kelch like family member 34. (646 aa)
	KLHL13	Kelch like family member 13. (700 aa)
	RHOBTB2	Rho related BTB domain containing 2. (727 aa)
	KLHL4	Kelch like family member 4. (595 aa)
	KLHL26	Kelch like family member 26. (607 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL6	BBS2	ENSCPOP00000004806	ENSCPOP00000003348	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 2 protein homolog.	0.760
ARL6	BBS5	ENSCPOP00000004806	ENSCPOP00000028238	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.730
ARL6	BBS7	ENSCPOP00000004806	ENSCPOP00000001110	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.806
ARL6	BBS9	ENSCPOP00000004806	ENSCPOP00000000840	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 9.	0.759
ARL6	Bbs1	ENSCPOP00000004806	ENSCPOP00000020681	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	BBS1 domain-containing protein.	0.827
ARL6	DOCK6	ENSCPOP00000004806	ENSCPOP00000020141	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Dedicator of cytokinesis 6; Belongs to the DOCK family.	0.401
ARL6	ENSCPOP00000021870	ENSCPOP00000004806	ENSCPOP00000021870	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.459
ARL6	H0UYD4_CAVPO	ENSCPOP00000004806	ENSCPOP00000002143	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.620
ARL6	KIFC2	ENSCPOP00000004806	ENSCPOP00000009215	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.651
ARL6	KLHL40	ENSCPOP00000004806	ENSCPOP00000016355	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Kelch like family member 40.	0.602
ARL6	KLHL41	ENSCPOP00000004806	ENSCPOP00000004472	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Kelch like family member 41.	0.616
ARL6	LOC100716676	ENSCPOP00000004806	ENSCPOP00000004586	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	TPR_REGION domain-containing protein.	0.759
ARL6	LZTFL1	ENSCPOP00000004806	ENSCPOP00000007283	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Leucine zipper transcription factor like 1.	0.594
ARL6	SLC27A2	ENSCPOP00000004806	ENSCPOP00000006673	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Solute carrier family 27 member 2.	0.531
ARL6	SLC27A3	ENSCPOP00000004806	ENSCPOP00000008497	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Solute carrier family 27 member 3.	0.531
ARL6	TTC8	ENSCPOP00000004806	ENSCPOP00000000619	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Tetratricopeptide repeat domain 8.	0.797
BBS2	ARL6	ENSCPOP00000003348	ENSCPOP00000004806	Bardet-Biedl syndrome 2 protein homolog.	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	0.760
BBS2	BBS5	ENSCPOP00000003348	ENSCPOP00000028238	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.996
BBS2	BBS7	ENSCPOP00000003348	ENSCPOP00000001110	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.999
BBS2	BBS9	ENSCPOP00000003348	ENSCPOP00000000840	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 9.	0.999