6 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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gene neighborhood

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textmining

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protein homology

Your Input:
	APLF	Aprataxin and PNKP like factor. (498 aa)
	Lig1	DNA ligase. (909 aa)
	POLB	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (340 aa)
	LIG3	DNA ligase. (1012 aa)
	POLM	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (485 aa)
	XRCC1	X-ray repair cross complementing 1. (629 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLF	LIG3	ENSCPOP00000003188	ENSCPOP00000011732	Aprataxin and PNKP like factor.	DNA ligase.	0.809
APLF	Lig1	ENSCPOP00000003188	ENSCPOP00000003796	Aprataxin and PNKP like factor.	DNA ligase.	0.603
APLF	POLB	ENSCPOP00000003188	ENSCPOP00000009487	Aprataxin and PNKP like factor.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.815
APLF	POLM	ENSCPOP00000003188	ENSCPOP00000013323	Aprataxin and PNKP like factor.	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.	0.460
APLF	XRCC1	ENSCPOP00000003188	ENSCPOP00000031519	Aprataxin and PNKP like factor.	X-ray repair cross complementing 1.	0.938
LIG3	APLF	ENSCPOP00000011732	ENSCPOP00000003188	DNA ligase.	Aprataxin and PNKP like factor.	0.809
LIG3	Lig1	ENSCPOP00000011732	ENSCPOP00000003796	DNA ligase.	DNA ligase.	0.662
LIG3	POLB	ENSCPOP00000011732	ENSCPOP00000009487	DNA ligase.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.922
LIG3	POLM	ENSCPOP00000011732	ENSCPOP00000013323	DNA ligase.	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.	0.732
LIG3	XRCC1	ENSCPOP00000011732	ENSCPOP00000031519	DNA ligase.	X-ray repair cross complementing 1.	0.999
Lig1	APLF	ENSCPOP00000003796	ENSCPOP00000003188	DNA ligase.	Aprataxin and PNKP like factor.	0.603
Lig1	LIG3	ENSCPOP00000003796	ENSCPOP00000011732	DNA ligase.	DNA ligase.	0.662
Lig1	POLB	ENSCPOP00000003796	ENSCPOP00000009487	DNA ligase.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.867
Lig1	POLM	ENSCPOP00000003796	ENSCPOP00000013323	DNA ligase.	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.	0.778
Lig1	XRCC1	ENSCPOP00000003796	ENSCPOP00000031519	DNA ligase.	X-ray repair cross complementing 1.	0.938
POLB	APLF	ENSCPOP00000009487	ENSCPOP00000003188	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Aprataxin and PNKP like factor.	0.815
POLB	LIG3	ENSCPOP00000009487	ENSCPOP00000011732	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	DNA ligase.	0.922
POLB	Lig1	ENSCPOP00000009487	ENSCPOP00000003796	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	DNA ligase.	0.867
POLB	POLM	ENSCPOP00000009487	ENSCPOP00000013323	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.	0.744
POLB	XRCC1	ENSCPOP00000009487	ENSCPOP00000031519	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	X-ray repair cross complementing 1.	0.995