(5 nodes) Mixed, incl. Ribosomal protein S2, and IRE1-RACK1-PP2A complex network (Cavia porcellus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	RPSA	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa)
	RACK1	Receptor for activated C kinase 1. (317 aa)
	EEF2	Eukaryotic translation elongation factor 2. (815 aa)
	RPL7A	Ribosomal protein L7a. (260 aa)
	RPL15	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEF2	RACK1	ENSCPOP00000014155	ENSCPOP00000007831	Eukaryotic translation elongation factor 2.	Receptor for activated C kinase 1.	0.999
EEF2	RPL15	ENSCPOP00000014155	ENSCPOP00000032580	Eukaryotic translation elongation factor 2.	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.	0.999
EEF2	RPL7A	ENSCPOP00000014155	ENSCPOP00000030687	Eukaryotic translation elongation factor 2.	Ribosomal protein L7a.	0.999
EEF2	RPSA	ENSCPOP00000014155	ENSCPOP00000007823	Eukaryotic translation elongation factor 2.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]	0.999
RACK1	EEF2	ENSCPOP00000007831	ENSCPOP00000014155	Receptor for activated C kinase 1.	Eukaryotic translation elongation factor 2.	0.999
RACK1	RPL15	ENSCPOP00000007831	ENSCPOP00000032580	Receptor for activated C kinase 1.	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.	0.999
RACK1	RPL7A	ENSCPOP00000007831	ENSCPOP00000030687	Receptor for activated C kinase 1.	Ribosomal protein L7a.	0.999
RACK1	RPSA	ENSCPOP00000007831	ENSCPOP00000007823	Receptor for activated C kinase 1.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]	0.999
RPL15	EEF2	ENSCPOP00000032580	ENSCPOP00000014155	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.	Eukaryotic translation elongation factor 2.	0.999
RPL15	RACK1	ENSCPOP00000032580	ENSCPOP00000007831	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.	Receptor for activated C kinase 1.	0.999
RPL15	RPL7A	ENSCPOP00000032580	ENSCPOP00000030687	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.	Ribosomal protein L7a.	0.999
RPL15	RPSA	ENSCPOP00000032580	ENSCPOP00000007823	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]	0.999
RPL7A	EEF2	ENSCPOP00000030687	ENSCPOP00000014155	Ribosomal protein L7a.	Eukaryotic translation elongation factor 2.	0.999
RPL7A	RACK1	ENSCPOP00000030687	ENSCPOP00000007831	Ribosomal protein L7a.	Receptor for activated C kinase 1.	0.999
RPL7A	RPL15	ENSCPOP00000030687	ENSCPOP00000032580	Ribosomal protein L7a.	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.	0.999
RPL7A	RPSA	ENSCPOP00000030687	ENSCPOP00000007823	Ribosomal protein L7a.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]	0.999
RPSA	EEF2	ENSCPOP00000007823	ENSCPOP00000014155	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]	Eukaryotic translation elongation factor 2.	0.999
RPSA	RACK1	ENSCPOP00000007823	ENSCPOP00000007831	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]	Receptor for activated C kinase 1.	0.999
RPSA	RPL15	ENSCPOP00000007823	ENSCPOP00000032580	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.	0.999
RPSA	RPL7A	ENSCPOP00000007823	ENSCPOP00000030687	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]	Ribosomal protein L7a.	0.999