57 items (Cavia porcellus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	GNL3	G protein nucleolar 3. (518 aa)
	GNL1	G protein nucleolar 1 (putative). (608 aa)
	DDX27	DEAD-box helicase 27; Belongs to the DEAD box helicase family. (765 aa)
	DDX56	DEAD-box helicase 56. (547 aa)
	Pes1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (590 aa)
	NIP7	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	EBNA1BP2	EBNA1 binding protein 2. (305 aa)
	BOP1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (734 aa)
	LOC100713157	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (404 aa)
	DDX24	DEAD-box helicase 24. (841 aa)
	RBM28	RNA binding motif protein 28. (758 aa)
	RPF2	Ribosome production factor 2 homolog. (306 aa)
	NIFK	Nucleolar protein interacting with the FHA domain of MKI67. (295 aa)
	DDX18	RNA helicase. (656 aa)
	RRP15	Ribosomal RNA processing 15 homolog. (281 aa)
	NSUN2	NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (765 aa)
	WDR74	WD repeat domain 74. (384 aa)
	Pum3	PUM-HD domain-containing protein. (648 aa)
	WDR12	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
	RSL24D1	Ribosomal L24 domain containing 1. (163 aa)
	NOC3L	Nucleolar complex protein 3 homolog. (800 aa)
	RSL1D1	Ribosomal L1 domain containing 1. (468 aa)
	KCTD19	Potassium channel tetramerization domain containing 19. (930 aa)
	FTSJ3	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (838 aa)
	GTPBP4	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
	DDX31	RNA helicase. (736 aa)
	RPF1	Ribosome production factor 1 homolog. (349 aa)
	NOP9	NOP9 nucleolar protein. (643 aa)
	RBM34	RNA binding motif protein 34. (430 aa)
	GNL3L	G protein nucleolar 3 like. (574 aa)
	NOP53	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (476 aa)
	P2RY1	P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. (373 aa)
	H0W0X5_CAVPO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (420 aa)
	P2RY11	Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (408 aa)
	PES1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (549 aa)
	LOC100716855	Brix domain-containing protein. (368 aa)
	Nop2	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (787 aa)
	GNL2	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (708 aa)
	RRS1	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (357 aa)
	BRIX1	Biogenesis of ribosomes BRX1. (346 aa)
	CEBPZ	CCAAT enhancer binding protein zeta. (1055 aa)
	NSA2	NSA2 ribosome biogenesis factor. (260 aa)
	RRP1	Ribosomal RNA processing 1. (448 aa)
	RRP1B	Ribosomal RNA processing 1B. (719 aa)
	SURF6	Surfeit 6. (358 aa)
	PES1-2	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (563 aa)
	ENSCPOP00000026253	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (565 aa)
	MRTO4	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (241 aa)
	DDX55	RNA helicase. (628 aa)
	ZNF593	Zinc finger protein 593. (134 aa)
	PAK1IP1	PAK1 interacting protein 1. (387 aa)
	PWP1	PWP1 homolog, endonuclein. (500 aa)
	RBM19	RNA binding motif protein 19. (961 aa)
	ENSCPOP00000031848	PUM-HD domain-containing protein. (204 aa)
	Nol12	Uncharacterized protein. (214 aa)
	ENSCPOP00000033053	Protein MAK16 homolog; Belongs to the MAK16 family. (256 aa)
	NOC2L	NOC2 like nucleolar associated transcriptional repressor. (799 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOP1	BRIX1	ENSCPOP00000004912	ENSCPOP00000020277	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Biogenesis of ribosomes BRX1.	0.999
BOP1	CEBPZ	ENSCPOP00000004912	ENSCPOP00000020612	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	CCAAT enhancer binding protein zeta.	0.976
BOP1	DDX18	ENSCPOP00000004912	ENSCPOP00000006796	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.999
BOP1	DDX24	ENSCPOP00000004912	ENSCPOP00000005309	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	DEAD-box helicase 24.	0.975
BOP1	DDX27	ENSCPOP00000004912	ENSCPOP00000001816	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	DEAD-box helicase 27; Belongs to the DEAD box helicase family.	0.985
BOP1	DDX31	ENSCPOP00000004912	ENSCPOP00000012833	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.960
BOP1	DDX55	ENSCPOP00000004912	ENSCPOP00000029869	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.995
BOP1	DDX56	ENSCPOP00000004912	ENSCPOP00000003036	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	DEAD-box helicase 56.	0.986
BOP1	EBNA1BP2	ENSCPOP00000004912	ENSCPOP00000004665	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	EBNA1 binding protein 2.	0.999
BOP1	ENSCPOP00000026253	ENSCPOP00000004912	ENSCPOP00000026253	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.	0.797
BOP1	ENSCPOP00000031848	ENSCPOP00000004912	ENSCPOP00000031848	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	PUM-HD domain-containing protein.	0.860
BOP1	ENSCPOP00000033053	ENSCPOP00000004912	ENSCPOP00000033053	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.990
BOP1	FTSJ3	ENSCPOP00000004912	ENSCPOP00000010234	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.	0.999
BOP1	GNL1	ENSCPOP00000004912	ENSCPOP00000001753	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	G protein nucleolar 1 (putative).	0.961
BOP1	GNL2	ENSCPOP00000004912	ENSCPOP00000019529	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.994
BOP1	GNL3	ENSCPOP00000004912	ENSCPOP00000000247	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	G protein nucleolar 3.	0.997
BOP1	GNL3L	ENSCPOP00000004912	ENSCPOP00000014084	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	G protein nucleolar 3 like.	0.997
BOP1	GTPBP4	ENSCPOP00000004912	ENSCPOP00000012373	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.999
BOP1	H0W0X5_CAVPO	ENSCPOP00000004912	ENSCPOP00000016613	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.983
BOP1	KCTD19	ENSCPOP00000004912	ENSCPOP00000009765	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Potassium channel tetramerization domain containing 19.	0.993